Zinc-mediated inhibition of GABA(A) receptors: discrete binding sites underlie subtype specificity. - Test2 - elhamkhani - TriplyDB

Zinc-mediated inhibition of GABA(A) receptors: discrete binding sites underlie subtype specificity.

Zinc-mediated inhibition of GABA(A) receptors: discrete binding sites underlie subtype specificity.

http://www.wikidata.org/entity/Q34184057

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In silico identification and expression of SLC30 family genes: an expressed sequence tag data mining strategy for the characterization of zinc transporters' tissue expression SNARE-dependent upregulation of potassium chloride co-transporter 2 activity after metabotropic zinc receptor activation in rat cortical neurons in vitro The zinc sensing receptor, a link between zinc and cell signaling Selective block of the human 2-P domain potassium channel, TASK-3, and the native leak potassium current, IKSO, by zinc Ionotropic GABA receptor antagonism-induced adverse outcome pathways for potential neurotoxicity biomarkers Redox and trace metal regulation of ion channels in the pain pathway Methods for recording and measuring tonic GABAA receptor-mediated inhibition Inhibition of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC by Divalent Cations Molecular basis for zinc potentiation at strychnine-sensitive glycine receptors Protein kinase C epsilon regulates gamma-aminobutyrate type A receptor sensitivity to ethanol and benzodiazepines through phosphorylation of gamma2 subunits Fragrant dioxane derivatives identify beta1-subunit-containing GABAA receptors Molecular and biophysical basis of glutamate and trace metal modulation of voltage-gated Ca(v)2.3 calcium channels.Different forms of glycine- and GABA(A)-receptor mediated inhibitory synaptic transmission in mouse superficial and deep dorsal horn neurons GABA and glycine as neurotransmitters: a brief history.An epilepsy-related region in the GABA(A) receptor mediates long-distance effects on GABA and benzodiazepine binding sites.Abnormal GABAA receptors from the human epileptic hippocampal subiculum microtransplanted to Xenopus oocytes.Zinc inhibition of gamma-aminobutyric acid transporter 4 (GAT4) reveals a link between excitatory and inhibitory neurotransmission The short splice variant of the gamma 2 subunit acts as an external modulator of GABA(A) receptor function.GABA coordinates with insulin in regulating secretory function in pancreatic INS-1 β-cells.Menthol enhances phasic and tonic GABAA receptor-mediated currents in midbrain periaqueductal grey neurons.Trafficking and potential assembly patterns of epsilon-containing GABAA receptors.An intersubunit zinc binding site in rat P2X2 receptors Benzodiazepine modulation of partial agonist efficacy and spontaneously active GABA(A) receptors supports an allosteric model of modulation.Synaptically released zinc gates long-term potentiation in fear conditioning pathways.Rescue of impaired fear extinction and normalization of cortico-amygdala circuit dysfunction in a genetic mouse model by dietary zinc restriction Pharmacological characterisation of murine α4β1δ GABAA receptors expressed in Xenopus oocytes.Synaptically released zinc triggers metabotropic signaling via a zinc-sensing receptor in the hippocampus.GABA(A) receptor modulation by terpenoids from Sideritis extracts.GABAA receptor subunit profiles of tangentially migrating neurons derived from the medial ganglionic eminence.Upregulation of KCC2 activity by zinc-mediated neurotransmission via the mZnR/GPR39 receptor Functional characterization of the 1,5-benzodiazepine clobazam and its major active metabolite N-desmethylclobazam at human GABA(A) receptors expressed in Xenopus laevis oocytes.The TM2 6' position of GABA(A) receptors mediates alcohol inhibition 2'-Methoxy-6-methylflavone: a novel anxiolytic and sedative with subtype selective activating and modulating actions at GABA(A) receptors.Neurosteroids and GABA-A Receptor Function.Zinc-specific autometallographic in vivo selenium methods: tracing of zinc-enriched (ZEN) terminals, ZEN pathways, and pools of zinc ions in a multitude of other ZEN cells.Studies of ethanol actions on recombinant delta-containing gamma-aminobutyric acid type A receptors yield contradictory results Discovery of allosteric modulators for GABAA receptors by ligand-directed chemistry.The neurobiology of zinc in health and disease.Deleterious Rare Variants Reveal Risk for Loss of GABAA Receptor Function in Patients with Genetic Epilepsy and in the General Population.Neonatal epilepsy syndromes and GEFS+: mechanistic considerations.

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P2860

Zinc-mediated inhibition of GABA(A) receptors: discrete binding sites underlie subtype specificity.

http://www.wikidata.org/entity/Q34184057

description

2003 nî lūn-bûn

@nan

2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի ապրիլին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Zinc-mediated inhibition of GABA

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Zinc-mediated inhibition of GA ...... underlie subtype specificity.

@ast

Zinc-mediated inhibition of GA ...... underlie subtype specificity.

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type

label

Zinc-mediated inhibition of GABA

@nl

Zinc-mediated inhibition of GA ...... underlie subtype specificity.

@ast

Zinc-mediated inhibition of GA ...... underlie subtype specificity.

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prefLabel

Zinc-mediated inhibition of GABA

@nl

Zinc-mediated inhibition of GA ...... underlie subtype specificity.

@ast

Zinc-mediated inhibition of GA ...... underlie subtype specificity.

@en

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Nature Neuroscience

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Zinc-mediated inhibition of GA ...... underlie subtype specificity.

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Alastair M Hosie

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Emma L Dunne

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Trevor G Smart

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P2860

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

Two gamma2L subunit domains confer low Zn2+ sensitivity to ternary GABA(A) receptors

Interaction of H+ and Zn2+ on recombinant and native rat neuronal GABAA receptors

Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel

Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+

Zinc coordination sphere in biochemical zinc sites.

Synaptically released zinc: physiological functions and pathological effects.

Stoichiometry of a ligand-gated ion channel determined by fluorescence energy transfer.

Developmental change of GABA(A) receptor-mediated current in rat hippocampus.

Anxiety over GABA(A) receptor structure relieved by AChBP.

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Robert J. Harvey

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