DNA damage in Nijmegen Breakage Syndrome cells leads to PARP hyperactivation and increased oxidative stress.
about
Oxidative stress and mitochondrial dysfunction across broad-ranging pathologies: toward mitochondria-targeted clinical strategies.Functional deficiency of NBN, the Nijmegen breakage syndrome protein, in a p.R215W mutant breast cancer cell line.Functional characterization of 8-oxoguanine DNA glycosylase of Trypanosoma cruzi.Susceptibility to DNA damage as a molecular mechanism for non-syndromic cleft lip and palate.Identification of the interactors of human nibrin (NBN) and of its 26 kDa and 70 kDa fragments arising from the NBN 657del5 founder mutation.Prevalence of Germline Mutations in Genes Engaged in DNA Damage Repair by Homologous Recombination in Patients with Triple-Negative and Hereditary Non-Triple-Negative Breast CancersEffect of irradiation on DNA synthesis, NBN gene expression and chromosomal stability in cells with NBN mutations.Ibrutinib synergizes with poly(ADP-ribose) glycohydrolase inhibitors to induce cell death in AML cells via a BTK-independent mechanismOxidative stress, mitochondrial abnormalities and antioxidant defense in Ataxia-telangiectasia, Bloom syndrome and Nijmegen breakage syndrome.Mitochondrial dysfunction and potential anticancer therapy.Oxidative stress-driven pulmonary inflammation and fibrosis in a mouse model of human ataxia-telangiectasia.Comparison of Selected Parameters of Redox Homeostasis in Patients with Ataxia-Telangiectasia and Nijmegen Breakage Syndrome.Increased oxidative stress mediates the antitumor effect of PARP inhibition in ovarian cancer.Perturbed autophagy and DNA repair converge to promote neurodegeneration in amyotrophic lateral sclerosis and dementia.
P2860
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P2860
DNA damage in Nijmegen Breakage Syndrome cells leads to PARP hyperactivation and increased oxidative stress.
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
DNA damage in Nijmegen Breakag ...... nd increased oxidative stress.
@ast
DNA damage in Nijmegen Breakag ...... nd increased oxidative stress.
@en
DNA damage in Nijmegen Breakag ...... nd increased oxidative stress.
@nl
type
label
DNA damage in Nijmegen Breakag ...... nd increased oxidative stress.
@ast
DNA damage in Nijmegen Breakag ...... nd increased oxidative stress.
@en
DNA damage in Nijmegen Breakag ...... nd increased oxidative stress.
@nl
prefLabel
DNA damage in Nijmegen Breakag ...... nd increased oxidative stress.
@ast
DNA damage in Nijmegen Breakag ...... nd increased oxidative stress.
@en
DNA damage in Nijmegen Breakag ...... nd increased oxidative stress.
@nl
P2093
P2860
P1433
P1476
DNA damage in Nijmegen Breakag ...... nd increased oxidative stress.
@en
P2093
Alexander Bürkle
Bastian Salewsky
Harald Krenzlin
Ilja Demuth
Kathrin Weidele
Martin Digweed
Petra Wessendorf
P2860
P304
P356
10.1371/JOURNAL.PGEN.1002557
P407
P577
2012-03-01T00:00:00Z