Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells
about
The interaction between the PARP10 protein and the NS1 protein of H5N1 AIV and its effect on virus replicationDynamics of DNA damage response proteins at DNA breaks: a focus on protein modificationsPARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibilityMicroirradiation techniques in radiobiological researchPleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammationPARPs and the DNA damage responseA New Nanobody-Based Biosensor to Study Endogenous PARP1 In Vitro and in Live Human CellsUnderstanding specific functions of PARP-2: new lessons for cancer therapyThe structural basis of XRCC1-mediated DNA repairCombinations of PARP Inhibitors with Temozolomide Drive PARP1 Trapping and Apoptosis in Ewing's SarcomaSam68 Is Required for DNA Damage Responses via Regulating Poly(ADP-ribosyl)ationX-ray repair cross complementing protein 1 in base excision repair.Analyzing structure-function relationships of artificial and cancer-associated PARP1 variants by reconstituting TALEN-generated HeLa PARP1 knock-out cells.Recruitment of RNA polymerase II cofactor PC4 to DNA damage sitesStructure/function analysis of PARP-1 in oxidative and nitrosative stress-induced monomeric ADPR formation.Biological dose estimation of UVA laser microirradiation utilizing charged particle-induced protein foci.A novel and simple micro-irradiation technique for creating localized DNA double-strand breaks.The BRCT domain of PARP-1 is required for immunoglobulin gene conversion.Red Si-rhodamine drug conjugates enable imaging in GFP cells.Suicidal cross-linking of PARP-1 to AP site intermediates in cells undergoing base excision repair.PARP-2 and PARP-3 are selectively activated by 5' phosphorylated DNA breaks through an allosteric regulatory mechanism shared with PARP-1.PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms.Damage site chromatin: open or closed?XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damageInhibition of poly (ADP-Ribose) polymerase-1 in telomerase deficient mouse embryonic fibroblasts increases arsenite-induced genome instabilityThe role of ADP-ribosylation in regulating DNA double-strand break repairPoly(ADP-ribose)-mediated interplay of XPA and PARP1 leads to reciprocal regulation of protein function.4D chromatin dynamics in cycling cells: Theodor Boveri's hypotheses revisited.DNA damage in Nijmegen Breakage Syndrome cells leads to PARP hyperactivation and increased oxidative stress.The alternative end-joining pathway for repair of DNA double-strand breaks requires PARP1 but is not dependent upon microhomologies.Targeting poly(ADP-ribose) polymerase activity for cancer therapy.Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors.Kinetics of endogenous mouse FEN1 in base excision repair.Hyperactivation of PARP triggers nonhomologous end-joining in repair-deficient mouse fibroblasts.SIRT7 promotes genome integrity and modulates non-homologous end joining DNA repair.Sirtuins and DNA damage repair: SIRT7 comes to play.Spatiotemporal dynamics of DNA repair proteins following laser microbeam induced DNA damage - when is a DSB not a DSB?Highlighting the DNA damage response with ultrashort laser pulses in the near infrared and kinetic modeling.DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repairNew paradigms in the repair of oxidative damage in human genome: mechanisms ensuring repair of mutagenic base lesions during replication and involvement of accessory proteins.
P2860
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P2860
Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Feedback-regulated poly
@nl
Feedback-regulated poly(ADP-ri ...... to DNA damage in living cells
@ast
Feedback-regulated poly(ADP-ri ...... to DNA damage in living cells
@en
type
label
Feedback-regulated poly
@nl
Feedback-regulated poly(ADP-ri ...... to DNA damage in living cells
@ast
Feedback-regulated poly(ADP-ri ...... to DNA damage in living cells
@en
prefLabel
Feedback-regulated poly
@nl
Feedback-regulated poly(ADP-ri ...... to DNA damage in living cells
@ast
Feedback-regulated poly(ADP-ri ...... to DNA damage in living cells
@en
P2093
P2860
P356
P1476
Feedback-regulated poly(ADP-ri ...... to DNA damage in living cells
@en
P2093
Heinrich Leonhardt
Jean-Christophe Amé
Oliver Mortusewicz
Valérie Schreiber
P2860
P304
P356
10.1093/NAR/GKM933
P407
P577
2007-11-03T00:00:00Z