A dominant-negative mutant of human poly(ADP-ribose) polymerase affects cell recovery, apoptosis, and sister chromatid exchange following DNA damage
about
Functional association of poly(ADP-ribose) polymerase with DNA polymerase alpha-primase complex: a link between DNA strand break detection and DNA replicationXRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damagePoly(ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombinationARTD1 (PARP1) activation and NAD(+) in DNA repair and cell deathStructure of the catalytic fragment of poly(AD-ribose) polymerase from chickenDNA excision repair and DNA damage-induced apoptosis are linked to Poly(ADP-ribosyl)ation but have different requirements for p53Specific interaction of DNA polymerase beta and DNA ligase I in a multiprotein base excision repair complex from bovine testisPoly(ADP-ribosyl)ation reactions in the regulation of nuclear functionsPoly(ADP-ribose) polymerase-1 and its cleavage products differentially modulate cellular protection through NF-kappaB-dependent signalingPoly(ADP-ribose) polymerase in DNA damage-response pathway: implications for radiation oncology.Sensing DNA damage by PARP-like fingers.A cellular survival switch: poly(ADP-ribosyl)ation stimulates DNA repair and silences transcription.Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies.Inhibition of poly(ADP-ribose) polymerase activity is insufficient to induce tetraploidy.DNA repair defect in poly(ADP-ribose) polymerase-deficient cell lines.Poly(ADP-ribosyl)ation of p53 in vitro and in vivo modulates binding to its DNA consensus sequence.Misregulation of gene expression in primary fibroblasts lacking poly(ADP-ribose) polymeraseEnhanced killing of cancer cells by poly(ADP-ribose) polymerase inhibitors and topoisomerase I inhibitors reflects poisoning of both enzymes.Efficient retroviral infection of mammalian cells is blocked by inhibition of poly(ADP-ribose) polymerase activityHypersensitivity phenotypes associated with genetic and synthetic inhibitor-induced base excision repair deficiencyNew opportunities in chemosensitization and radiosensitization: modulating the DNA-damage response.Poly(ADP-ribosylation) and genomic stability.Poly(ADP-ribosyl)ation in mammalian ageing.Proteolysis and the biochemistry of life-or-death decisions.Niacin restriction upregulates NADPH oxidase and reactive oxygen species (ROS) in human keratinocytes.Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells.Chromosomal aberrations in PARP(-/-) mice: genome stabilization in immortalized cells by reintroduction of poly(ADP-ribose) polymerase cDNA.Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes.Structural recognition of DNA by poly(ADP-ribose)polymerase-like zinc finger families.Effective sensitization of temozolomide by ABT-888 is lost with development of temozolomide resistance in glioblastoma xenograft lines.Inhibition of the activity of poly (ADP-ribose) polymerase reduces heart ischaemia/reperfusion injury via suppressing JNK-mediated AIF translocation.Poly ADP-ribose polymerase-1 and health.Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases.Leptin induces apoptosis via ERK/cPLA2/cytochrome c pathway in human bone marrow stromal cells.Role of PARP-1 in prostate cancer.Response of Dictyostelium discoideum to UV-C and involvement of poly (ADP-ribose) polymerase.Coordination of DNA single strand break repair.Failure of poly(ADP-ribose) polymerase cleavage by caspases leads to induction of necrosis and enhanced apoptosis.Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling.Base excision repair is efficient in cells lacking poly(ADP-ribose) polymerase 1.
P2860
Q24319674-E889AF4D-34B0-4ADE-88BD-D8256E14D574Q24522502-250DD221-C92E-40C1-B3BB-48F564305396Q24685242-8FB0A41A-5AA9-4CAF-89A0-77481D6D8E56Q27027461-0F658054-1737-4E7E-8EB5-F5DB81EA747EQ27733281-A1015BF2-BA00-4410-882F-8EECD7036EF3Q28115289-56490181-1B62-4404-A59E-88311AC5C4B4Q28645719-30452112-040E-44FC-9A20-0ACD71877E12Q29617672-1EDD166B-462A-4C5D-B047-06C3FD26E1FEQ33578933-38053171-D2A3-4276-B1D9-E8FE84E25A73Q33920728-E0DEA556-536F-41AC-87AB-ABD1BC92C3D4Q33987203-647DC784-2416-4C65-BEEE-8A35B0C75892Q34269353-CF3B5FD7-B6C3-4756-B93E-F6147426D674Q34536666-5C372E0B-0932-4E12-A731-0AC26D56B6C5Q34570024-81B5B86F-3DC1-4A30-936A-879C05C88962Q34668455-F8DC6564-23B4-4263-AAC0-1C57C4149E90Q34779828-CC060558-36F2-4A00-B977-003B6AD04B4DQ35271750-5B1E4DCF-EB04-4945-A168-7B80D21E4718Q35763155-8D8A576B-A34B-4F34-BD5D-0DE9346F8847Q35861994-0105AE0A-7A88-434A-BB13-A19B968F00F8Q35876447-F1523D82-F4C0-4AFF-901F-33B3190BA6FCQ36118418-2EFCA731-4DA8-4CAE-87BF-18281D33103CQ36164734-51CEFBCE-967B-435C-BF7A-EF92FB190281Q36360594-62B0BDDE-C09B-4A40-A534-E510D4EA01E5Q36366734-FA22EA48-C3A0-4458-AC80-A167EAF3E403Q36570801-EF8EF549-963E-4422-A64B-CB8DEC839EF5Q36654891-FD2C9357-C177-4FED-9ECC-99D3E24A0F6DQ36668248-65D808F2-9F25-4D95-8B72-39F2E51B8102Q36913813-27BB4642-6788-43BE-BE59-26EB6F903A33Q37063627-224345DA-7121-4A90-BAEC-F25DF8D9BB8AQ37216709-433F2677-4648-455C-A60E-6113A46E79ECQ37398277-399465E5-9949-4924-9E3D-7B3F5543D3B5Q37750189-7B04909D-BEEF-4754-A516-1C4D736CAB3BQ38191981-DD34908D-6584-4B5E-9328-0F1335AE5207Q38356187-4C5C51E2-0696-46BD-92AC-62C8C6F73F43Q38526322-1FBA1580-2A7E-4855-85CF-A34DBFCCB4CFQ39019715-2DB9A58D-070D-488C-91EE-2173EC76D02AQ39021578-CB7DCBCB-03A7-4E7B-9D22-9D2F639DAEB9Q39446494-7FD071CD-6F08-45EB-8064-BE3B8DD8218CQ39527042-8F47646E-4234-472F-A9E0-E40A0F3447B4Q39584636-FFF451D0-34DF-45CE-BA94-9B5CE2675A9A
P2860
A dominant-negative mutant of human poly(ADP-ribose) polymerase affects cell recovery, apoptosis, and sister chromatid exchange following DNA damage
description
1995 nî lūn-bûn
@nan
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
A dominant-negative mutant of ...... exchange following DNA damage
@ast
A dominant-negative mutant of ...... exchange following DNA damage
@en
A dominant-negative mutant of ...... exchange following DNA damage
@nl
type
label
A dominant-negative mutant of ...... exchange following DNA damage
@ast
A dominant-negative mutant of ...... exchange following DNA damage
@en
A dominant-negative mutant of ...... exchange following DNA damage
@nl
prefLabel
A dominant-negative mutant of ...... exchange following DNA damage
@ast
A dominant-negative mutant of ...... exchange following DNA damage
@en
A dominant-negative mutant of ...... exchange following DNA damage
@nl
P2093
P2860
P356
P1476
A dominant-negative mutant of ...... exchange following DNA damage
@en
P2093
De Murcia G
De Murcia JM
Grunwald D
Schreiber V
P2860
P304
P356
10.1073/PNAS.92.11.4753
P407
P577
1995-05-01T00:00:00Z