Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma.
about
Promoter methylation-associated loss of ID4 expression is a marker of tumour recurrence in human breast cancerIdentification of novel cholesteatoma-related gene expression signatures using full-genome microarraysType II arginine methyltransferase PRMT5 regulates gene expression of inhibitors of differentiation/DNA binding Id2 and Id4 during glial cell differentiationId4 deficiency attenuates prostate development and promotes PIN-like lesions by regulating androgen receptor activity and expression of NKX3.1 and PTENHelicobacter pylori infection, oncogenic pathways and epigenetic mechanisms in gastric carcinogenesis.SSeCKS/Gravin/AKAP12 attenuates expression of proliferative and angiogenic genes during suppression of v-Src-induced oncogenesisInhibitor of differentiation 4 (Id4) is a potential tumor suppressor in prostate cancer.Elevated endogenous expression of the dominant negative basic helix-loop-helix protein ID1 correlates with significant centrosome abnormalities in human tumor cells.Inhibitor of differentiation 4 (ID4) inactivation promotes de novo steroidogenesis and castration-resistant prostate cancer.Global assessment of promoter methylation in a mouse model of cancer identifies ID4 as a putative tumor-suppressor gene in human leukemia.Increased ID4 expression, accompanied by mutant p53 accumulation and loss of BRCA1/2 proteins in triple-negative breast cancer, adversely affects survival.Epstein-Barr virus-specific methylation of human genes in gastric cancer cells.Epigenetic inactivation of inhibitor of differentiation 4 (Id4) correlates with prostate cancerHeritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer.A systematic comparison of quantitative high-resolution DNA methylation analysis and methylation-specific PCR.Similarity of aberrant DNA methylation in Barrett's esophagus and esophageal adenocarcinoma.Id-1, Id-2, and Id-3 co-expression correlates with prognosis in stage I and II lung adenocarcinoma patients treated with surgery and adjuvant chemotherapyDifferential methylation pattern of ID4, SFRP1, and SHP1 between acute myeloid leukemia and chronic myeloid leukemiaInhibitor of differentiation proteins do not influence prognosis of biliary tract cancer.Major signaling pathways in intestinal stem cells.Inhibitor of differentiation 4 (ID4): From development to cancerInhibitor of differentiation 4 (ID4) acts as an inhibitor of ID-1, -2 and -3 and promotes basic helix loop helix (bHLH) E47 DNA binding and transcriptional activity.EZH2 dependent H3K27me3 is involved in epigenetic silencing of ID4 in prostate cancer.Id4 suppresses MMP2-mediated invasion of glioblastoma-derived cells by direct inactivation of Twist1 function.Id4 dependent acetylation restores mutant-p53 transcriptional activity.The Id-protein family in developmental and cancer-associated pathways.ID4 is frequently downregulated and partially hypermethylated in prostate cancer.Targeting Id1 and Id3 inhibits peritoneal metastasis of gastric cancer.ID4: a new player in the cancer arena.Induction of Lumen Formation in a Three-dimensional Model of Mammary Morphogenesis by Transcriptional Regulator ID4: ROLE OF CaMK2D IN THE EPIGENETIC REGULATION OF ID4 GENE EXPRESSION.Frequent reduced expression of alpha-1B-adrenergic receptor caused by aberrant promoter methylation in gastric cancers.Epigenetic silencing of Id4 identifies a glioblastoma subgroup with a better prognosis as a consequence of an inhibition of angiogenesis.Reduced expression of EphB2 that parallels invasion and metastasis in colorectal tumours.Inhibitor of DNA binding-4 promotes angiogenesis and growth of glioblastoma multiforme by elevating matrix GLA levels.Id proteins expression in prostate cancer: high-level expression of Id-4 in primary prostate cancer is associated with development of metastases.Comparative epigenomics of leukemia.Id4 protein is highly expressed in triple-negative breast carcinomas: possible implications for BRCA1 downregulation.Epigenetic regulation of ID4 in breast cancer: tumor suppressor or oncogene?
P2860
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P2860
Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma.
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma.
@ast
Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma.
@en
Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma.
@nl
type
label
Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma.
@ast
Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma.
@en
Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma.
@nl
prefLabel
Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma.
@ast
Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma.
@en
Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma.
@nl
P2093
P2860
P356
P1433
P1476
Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma
@en
P2093
Agnes Sze Wah Chan
Annie Shuk Yee Chan
Kent Man Chu
Siu Tsan Yuen
Tsun Leung Chan
Wai Yin Tsui
P2860
P2888
P304
P356
10.1038/SJ.ONC.1206799
P407
P577
2003-10-01T00:00:00Z
P5875
P6179
1045401391