Akt/protein kinase B promotes organ growth in transgenic mice.
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Hairy-related transcription factors inhibit GATA-dependent cardiac gene expression through a signal-responsive mechanismCardiac regulation by phosphoinositide 3-kinases and PTENLiver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activityProtein kinase cascades in the regulation of cardiac hypertrophyLife with a single isoform of Akt: mice lacking Akt2 and Akt3 are viable but display impaired glucose homeostasis and growth deficienciesMolecular basis of physiological heart growth: fundamental concepts and new playersDeletion of MLIP (muscle-enriched A-type lamin-interacting protein) leads to cardiac hyperactivation of Akt/mammalian target of rapamycin (mTOR) and impaired cardiac adaptationPhosphorylation of the Twist1-family basic helix-loop-helix transcription factors is involved in pathological cardiac remodelingOverexpression of Akt1 enhances adipogenesis and leads to lipoma formation in zebrafishThe TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteinsRole for Akt3/protein kinase Bgamma in attainment of normal brain sizeThe alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouseThe loss of glypican-3 induces alterations in Wnt signalingEndocytosis machinery is required for beta1-adrenergic receptor-induced hypertrophy in neonatal rat cardiac myocytesRas GTPase-activating protein binds to Akt and is required for its activationMammalian target of rapamycin and protein kinase A signaling mediate the cardiac transcriptional response to glutamineNprl3 is required for normal development of the cardiovascular systemOverexpression of bone morphogenetic protein 10 in myocardium disrupts cardiac postnatal hypertrophic growthInpp5f is a polyphosphoinositide phosphatase that regulates cardiac hypertrophic responsivenessA model for obesity and gigantism due to disruption of the Ankrd26 geneNephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signalingRapamycin treatment augments both protein ubiquitination and Akt activation in pressure-overloaded rat myocardiumMammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4EAkt regulates growth by directly phosphorylating Tsc2Insulin Signaling and Heart Failure.Use of RNA interference-mediated gene silencing and adenoviral overexpression to elucidate the roles of AKT/protein kinase B isoforms in insulin actions.Deletion of PKBalpha/Akt1 affects thymic developmentMammalian target of rapamycin (mTOR) induces proliferation and de-differentiation responses to three coordinate pathophysiologic stimuli (mechanical strain, hypoxia, and extracellular matrix remodeling) in rat bladder smooth muscle.Mammalian target of rapamycin is a critical regulator of cardiac hypertrophy in spontaneously hypertensive rats.Validation of anti-aging drugs by treating age-related diseases.Deficiency of cardiac Acyl-CoA synthetase-1 induces diastolic dysfunction, but pathologic hypertrophy is reversed by rapamycinRegulation of the postnatal development of dopamine neurons of the substantia nigra in vivo by Akt/protein kinase B.Mitochondrial integrity: preservation through Akt/Pim-1 kinase signaling in the cardiomyocyteMelatonin and Fertoprotective Adjuvants: Prevention against Premature Ovarian Failure during Chemotherapy.Therapeutic strategies with oral fluoropyrimidine anticancer agent, S-1 against oral cancer.Akt1 in the cardiovascular system: friend or foe?Screening for acute IKr block is insufficient to detect torsades de pointes liability: role of late sodium current.The FoxO family in cardiac function and dysfunction.β-Adrenergic receptor-PI3K signaling crosstalk in mouse heart: elucidation of immediate downstream signaling cascades.TLR2 ligands induce cardioprotection against ischaemia/reperfusion injury through a PI3K/Akt-dependent mechanism
P2860
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P2860
Akt/protein kinase B promotes organ growth in transgenic mice.
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Akt/protein kinase B promotes organ growth in transgenic mice.
@ast
Akt/protein kinase B promotes organ growth in transgenic mice.
@en
Akt/protein kinase B promotes organ growth in transgenic mice.
@nl
type
label
Akt/protein kinase B promotes organ growth in transgenic mice.
@ast
Akt/protein kinase B promotes organ growth in transgenic mice.
@en
Akt/protein kinase B promotes organ growth in transgenic mice.
@nl
prefLabel
Akt/protein kinase B promotes organ growth in transgenic mice.
@ast
Akt/protein kinase B promotes organ growth in transgenic mice.
@en
Akt/protein kinase B promotes organ growth in transgenic mice.
@nl
P2093
P2860
P1476
Akt/protein kinase B promotes organ growth in transgenic mice.
@en
P2093
Julie R McMullen
Peter M Kang
Seigo Izumo
Tetsuo Shioi
Thomas F Franke
Toshiyuki Obata
P2860
P304
P356
10.1128/MCB.22.8.2799-2809.2002
P407
P577
2002-04-01T00:00:00Z