Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia.
about
Prognostic role of microRNA-150 in various carcinomas: a meta-analysisMYC and the art of microRNA maintenancec-MYC-miRNA circuitry: a central regulator of aggressive B-cell malignanciesMicroRNAs in B-cell lymphomas: how a complex biology gets more complexLin28: primal regulator of growth and metabolism in stem cellsEctopic microRNA-150-5p transcription sensitizes glucocorticoid therapy response in MM1S multiple myeloma cells but fails to overcome hormone therapy resistance in MM1R cellsMiR-150 impairs inflammatory cytokine production by targeting ARRB-2 after blocking CD28/B7 costimulatory pathway.miR-150 is downregulated in osteosarcoma and suppresses cell proliferation, migration and invasion by targeting ROCK1.ALOX5 exhibits anti-tumor and drug-sensitizing effects in MLL-rearranged leukemia.miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemiaMicroRNA-150 regulates the cytotoxicity of natural killers by targeting perforin-1MicroRNAs in Cancer Biology and Therapy: Current Status and Perspectives.Repression of let-7 by transforming growth factor-β1-induced Lin28 upregulates collagen expression in glomerular mesangial cells under diabetic conditions.Flt3 does not play a critical role in murine myeloid leukemias induced by MLL fusion genes.MicroRNA-150 expression induces myeloid differentiation of human acute leukemia cells and normal hematopoietic progenitorsTwo decades of leukemia oncoprotein epistasis: the MLL1 paradigm for epigenetic deregulation in leukemia.A microRNA signature predicts survival in early stage small-cell lung cancer treated with surgery and adjuvant chemotherapy.Human fibroblast reprogramming to pluripotent stem cells regulated by the miR19a/b-PTEN axis.Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program.The pathological role and prognostic impact of miR-181 in acute myeloid leukemiaRole of microRNA-150 in solid tumors.microRNA-150 promotes cervical cancer cell growth and survival by targeting FOXO4.Emerging role of transcription factor-microRNA-target gene feed-forward loops in cancer.Reversal of microRNA-150 silencing disadvantages crizotinib-resistant NPM-ALK(+) cell growthOverexpression and knockout of miR-126 both promote leukemogenesisCD46 Activation Regulates miR-150-Mediated Control of GLUT1 Expression and Cytokine Secretion in Human CD4+ T Cells.PBX3 is an important cofactor of HOXA9 in leukemogenesis.Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study.Identification of MLL-fusion/MYC⊣miR-26⊣TET1 signaling circuit in MLL-rearranged leukemia.PBX3 and MEIS1 Cooperate in Hematopoietic Cells to Drive Acute Myeloid Leukemias Characterized by a Core Transcriptome of the MLL-Rearranged DiseaseRNA-binding protein IGF2BP3 targeting of oncogenic transcripts promotes hematopoietic progenitor proliferation.miR-26a enhances miRNA biogenesis by targeting Lin28B and Zcchc11 to suppress tumor growth and metastasis.miR-9 is an essential oncogenic microRNA specifically overexpressed in mixed lineage leukemia-rearranged leukemia.TET1 plays an essential oncogenic role in MLL-rearranged leukemiaDevelopmental regulation of myeloerythroid progenitor function by the Lin28b-let-7-Hmga2 axis.Differential regulation of the c-Myc/Lin28 axis discriminates subclasses of rearranged MLL leukemiamiR-150 exerts antileukemia activity in vitro and in vivo through regulating genes in multiple pathwaysSynthesis and delivery of short, noncoding RNA by B lymphocytes.miR-150 Suppresses the Proliferation and Tumorigenicity of Leukemia Stem Cells by Targeting the Nanog Signaling Pathway.HSC commitment-associated epigenetic signature is prognostic in acute myeloid leukemia.
P2860
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P2860
Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia.
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Blockade of miR-150 maturation ...... d for MLL-associated leukemia.
@ast
Blockade of miR-150 maturation ...... d for MLL-associated leukemia.
@en
Blockade of miR-150 maturation ...... d for MLL-associated leukemia.
@nl
type
label
Blockade of miR-150 maturation ...... d for MLL-associated leukemia.
@ast
Blockade of miR-150 maturation ...... d for MLL-associated leukemia.
@en
Blockade of miR-150 maturation ...... d for MLL-associated leukemia.
@nl
prefLabel
Blockade of miR-150 maturation ...... d for MLL-associated leukemia.
@ast
Blockade of miR-150 maturation ...... d for MLL-associated leukemia.
@en
Blockade of miR-150 maturation ...... d for MLL-associated leukemia.
@nl
P2093
P2860
P1433
P1476
Blockade of miR-150 maturation ...... d for MLL-associated leukemia.
@en
P2093
Abdel Elkahloun
Chunjiang He
Colles Price
Gia-Ming Hong
Haomin Ren
Jianjun Chen
Jinhua Wang
P2860
P304
P356
10.1016/J.CCR.2012.08.028
P577
2012-10-01T00:00:00Z