A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits.
about
Src-family tyrosine kinases in activation of ERK-1 and p85/p110-phosphatidylinositol 3-kinase by G/CCKB receptorsThe EphA8 receptor regulates integrin activity through p110gamma phosphatidylinositol-3 kinase in a tyrosine kinase activity-independent mannerP110delta, a novel phosphoinositide 3-kinase in leukocytesThe human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein familiesCloning and characterization of a wortmannin-sensitive human phosphatidylinositol 4-kinaseA human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting systemG protein-coupled chemoattractant receptors regulate Lyn tyrosine kinase.Shc adapter protein signaling complexesRoles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gammaCloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmanninBinding of beta gamma subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinaseActivation of phosphoinositide 3-kinase by interaction with Ras and by point mutationUnderstanding molecular recognition by G protein βγ subunits on the path to pharmacological targetingIntegrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85 alpha with actin filaments and focal adhesion kinaseExpansion of signal transduction by G proteins. The second 15 years or so: from 3 to 16 alpha subunits plus betagamma dimersTargeting G protein coupled receptor-related pathways as emerging molecular therapiesPhosphoinositides: tiny lipids with giant impact on cell regulationPI3Kγ Is Critical for Dendritic Cell-Mediated CD8+ T Cell Priming and Viral Clearance during Influenza Virus InfectionSTT4 is an essential phosphatidylinositol 4-kinase that is a target of wortmannin in Saccharomyces cerevisiae.G Protein beta gamma subunits act on the catalytic domain to stimulate Bruton's agammaglobulinemia tyrosine kinaseAntifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug actionWortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reactionA specific role of phosphatidylinositol 3-kinase gamma. A regulation of autonomic Ca(2)+ oscillations in cardiac cellsEndocytosis machinery is required for beta1-adrenergic receptor-induced hypertrophy in neonatal rat cardiac myocytesActivation of phospholipase C-gamma by phosphatidylinositol 3,4,5-trisphosphateRac GTPase interacts specifically with phosphatidylinositol 3-kinaseNeutrophil cell surface receptors and their intracellular signal transduction pathways.Gi-mediated activation of the Ras/MAP kinase pathway involves a 100 kDa tyrosine-phosphorylated Grb2 SH3 binding protein, but not Src nor ShcDifferential sensitivity of phosphatidylinositol 3-kinase p110gamma to isoforms of G protein betagamma dimers.Src family tyrosine kinase regulates intracellular pH in cardiomyocytesPhosphorylation of the G protein gamma12 subunit regulates effector specificity.G protein-independent Ras/PI3K/F-actin circuit regulates basic cell motility.RACK1 regulates directional cell migration by acting on G betagamma at the interface with its effectors PLC beta and PI3K gamma.Prenylation-deficient G protein gamma subunits disrupt GPCR signaling in the zebrafishSynaptotagmin-mediated vesicle fusion regulates cell migration.Identification and characterization of the autophosphorylation sites of phosphoinositide 3-kinase isoforms beta and gamma.Defective chemokine signal integration in leukocytes lacking activator of G protein signaling 3 (AGS3)Phosphatidylinositol 3-kinase-gamma activates Bruton's tyrosine kinase in concert with Src family kinases.Morphine peripheral analgesia depends on activation of the PI3Kgamma/AKT/nNOS/NO/KATP signaling pathwayIdentification of a proline-rich sequence in the CD2 cytoplasmic domain critical for regulation of integrin-mediated adhesion and activation of phosphoinositide 3-kinaseEvidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5.
P2860
Q22010243-2DA91CFE-5F82-4C86-B47F-7DD69CFE74EDQ24291347-60D98680-B196-47BB-B803-CB7070286BCCQ24314825-15ADE58A-6584-4D1E-870B-F5C801D61A18Q24315862-1EDD376A-B42E-4A63-94A9-D60AF094B671Q24318156-135D6DD4-1805-4EC3-9B9D-1FC4E3483978Q24321185-39314BA4-3898-4481-A689-8E82D7DB9D87Q24324803-5F7547B1-1CFC-4B56-A6ED-EBA37E72ED4AQ24338089-253DE163-97FA-42AD-B693-8028EEC04D1FQ24530221-7D68F533-CC0A-412C-8ED3-5018BEB84677Q24562166-0D5FD4D4-005B-4CE7-BDBE-92E4E37EDD9FQ24563004-730A0105-52FB-4F29-82F1-A62BF0EE2788Q24635233-64901082-270D-4F9F-8658-34A9F392D70EQ24672645-9718B22B-1D7D-495B-BB12-0254AA30DA2EQ24681398-42310252-5EB0-4874-A3A1-F290CB226163Q26829964-60D075BF-8464-4118-8774-3008B2A78CDEQ27012953-A9EA807B-4B7A-4A59-90EC-9C40E299CC83Q27315032-38A0D685-888F-4066-A706-E0150DB5148CQ27930696-247C26AD-2267-4898-B760-0E6BB0D4E858Q28204220-6DF25F72-4EAB-4DF0-BF34-35A15FA06FE8Q28343624-B9B09957-69C9-4D54-BFD1-0655C90E6964Q28378871-D01BC5DF-6DEA-4894-918E-7D78EAE3491DQ28573309-B7EB4D84-C2B8-4E3B-B1F4-DA4349863ADDQ28578076-80B951AD-9DFE-4B1D-87B5-C07F1DD4EEFFQ28616287-18819756-9F81-4C6D-815B-A9BBFAF841A8Q28646209-A2CC0F57-D085-4F02-8B9F-7C4E1B715E33Q30009577-32869302-B3EC-47CD-BE09-BA849FB22C9FQ30176516-83AB808D-ECCF-466A-848A-3050C7F42004Q30434268-25505358-10D9-4E15-AD04-C5B29926390AQ30442099-12F75D08-2D0F-4131-811D-0C61FE23D9DBQ30472460-5D99D546-957B-44BE-B8F1-13A363EF107DQ30480512-27F06FFE-A936-4CE0-8205-CAE16987108FQ30483264-DAC61815-789D-4B60-9F13-3BAAD842CB1DQ30492154-17427427-B3F8-4B27-BEA3-E150F6593E5AQ30496918-90B51A07-77C5-4761-9086-4487D5061BBDQ31122634-9760E499-D4CB-4E22-9C37-8C90CD0856CAQ33675851-B705BA64-B697-4282-A457-525329F4F422Q33729893-EFB76A39-649E-460D-A9AE-31A5556EF95FQ33733102-88A081B7-A426-4D06-82DB-DB3360D5C523Q33778252-60C2EC5B-674C-4561-B223-C8B59E27EE1FQ33826723-5D575004-B7FB-4EBB-B856-5FA78686B7F4
P2860
A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits.
description
1994 nî lūn-bûn
@nan
1994 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
A novel phosphoinositide 3 kin ...... G protein beta gamma subunits.
@ast
A novel phosphoinositide 3 kin ...... G protein beta gamma subunits.
@en
A novel phosphoinositide 3 kin ...... G protein beta gamma subunits.
@nl
type
label
A novel phosphoinositide 3 kin ...... G protein beta gamma subunits.
@ast
A novel phosphoinositide 3 kin ...... G protein beta gamma subunits.
@en
A novel phosphoinositide 3 kin ...... G protein beta gamma subunits.
@nl
prefLabel
A novel phosphoinositide 3 kin ...... G protein beta gamma subunits.
@ast
A novel phosphoinositide 3 kin ...... G protein beta gamma subunits.
@en
A novel phosphoinositide 3 kin ...... G protein beta gamma subunits.
@nl
P2093
P1433
P1476
A novel phosphoinositide 3 kin ...... G protein beta gamma subunits.
@en
P2093
P356
10.1016/0092-8674(94)90237-2
P407
P577
1994-04-01T00:00:00Z