Dominant negative mutants of the yeast splicing factor Prp2 map to a putative cleft region in the helicase domain of DExD/H-box proteins.
about
Characterization of the ATPase and unwinding activities of the yeast DEAD-box protein Has1p and the analysis of the roles of the conserved motifsStructure-Based Mutational Analysis of the Hepatitis C Virus NS3 HelicaseThe DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome.A novel splicing factor, Yju2, is associated with NTC and acts after Prp2 in promoting the first catalytic reaction of pre-mRNA splicing.Prp43 is an essential RNA-dependent ATPase required for release of lariat-intron from the spliceosome.The G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosomeComprehensive mutational analysis of yeast DEXD/H box RNA helicases required for small ribosomal subunit synthesis.Contribution of DEAH-box protein DHX16 in human pre-mRNA splicingSingle-Molecule Pull-Down FRET to Dissect the Mechanisms of Biomolecular MachinesBiased Brownian ratcheting leads to pre-mRNA remodeling and capture prior to first-step splicing.Definition of a spliceosome interaction domain in yeast Prp2 ATPase.GPKOW is essential for pre-mRNA splicing in vitro and suppresses splicing defect caused by dominant-negative DHX16 mutation in vivo.Roles of DEAD-box proteins in RNA and RNP Folding.Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for sub2, an essential spliceosomal ATPase.The interaction of Prp2 with a defined region of the intron is required for the first splicing reaction.Structural toggle in the RNaseH domain of Prp8 helps balance splicing fidelity and catalytic efficiency.RNA helicase dynamics in pre-mRNA splicingInteraction between a G-patch protein and a spliceosomal DEXD/H-box ATPase that is critical for splicing.Mutations in PRP43 that uncouple RNA-dependent NTPase activity and pre-mRNA splicing function.Motifs IV and V in the DEAH box splicing factor Prp22 are important for RNA unwinding, and helicase-defective Prp22 mutants are suppressed by Prp8.Translation initiation factor 4A: a prototype member of dead-box protein family.Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing.
P2860
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P2860
Dominant negative mutants of the yeast splicing factor Prp2 map to a putative cleft region in the helicase domain of DExD/H-box proteins.
description
2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
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2000年論文
@zh-hk
2000年論文
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2000年論文
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2000年论文
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name
Dominant negative mutants of t ...... domain of DExD/H-box proteins.
@ast
Dominant negative mutants of t ...... domain of DExD/H-box proteins.
@en
Dominant negative mutants of t ...... domain of DExD/H-box proteins.
@nl
type
label
Dominant negative mutants of t ...... domain of DExD/H-box proteins.
@ast
Dominant negative mutants of t ...... domain of DExD/H-box proteins.
@en
Dominant negative mutants of t ...... domain of DExD/H-box proteins.
@nl
prefLabel
Dominant negative mutants of t ...... domain of DExD/H-box proteins.
@ast
Dominant negative mutants of t ...... domain of DExD/H-box proteins.
@en
Dominant negative mutants of t ...... domain of DExD/H-box proteins.
@nl
P2093
P2860
P1433
P1476
Dominant negative mutants of t ...... domain of DExD/H-box proteins
@en
P2093
P2860
P304
P356
10.1017/S1355838200992483
P407
P50
P577
2000-08-01T00:00:00Z