Epithelium-specific deletion of TGF-β receptor type II protects mice from bleomycin-induced pulmonary fibrosis. - Test2 - elhamkhani - TriplyDB

Epithelium-specific deletion of TGF-β receptor type II protects mice from bleomycin-induced pulmonary fibrosis.

Epithelium-specific deletion of TGF-β receptor type II protects mice from bleomycin-induced pulmonary fibrosis.

http://www.wikidata.org/entity/Q34428905

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Regulation of transforming growth factor-β1-driven lung fibrosis by galectin-3 Breakdown of Epithelial Barrier Integrity and Overdrive Activation of Alveolar Epithelial Cells in the Pathogenesis of Acute Respiratory Distress Syndrome and Lung Fibrosis Reciprocal regulation of TGF-β and reactive oxygen species: A perverse cycle for fibrosis Extracellular matrix as a contextual determinant of transforming growth factor-β signaling in epithelial-mesenchymal transition and in cancer Pulmonary fibrosis: patterns and perpetrators Ubiquitin E3 ligase FIEL1 regulates fibrotic lung injury through SUMO-E3 ligase PIAS4 FAK-related nonkinase is a multifunctional negative regulator of pulmonary fibrosis.Interactions between β-catenin and transforming growth factor-β signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP).Osteopontin enhances multi-walled carbon nanotube-triggered lung fibrosis by promoting TGF-ß1 activation and myofibroblast differentiation MLN4924 protects against bleomycin-induced pulmonary fibrosis by inhibiting the early inflammatory process Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis Tetraspanin CD151 protects against pulmonary fibrosis by maintaining epithelial integrity Role of the lysophospholipid mediators lysophosphatidic acid and sphingosine 1-phosphate in lung fibrosis.Alveolar epithelium: beyond the barrier.Regulation of transforming growth factor-beta1 (TGF-β1)-induced pro-fibrotic activities by circadian clock gene BMAL1.Focal Adhesion Kinase Regulates Hepatic Stellate Cell Activation and Liver Fibrosis.Arsenic trioxide inhibits transforming growth factor-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo.Gene expression profiles reveal molecular mechanisms involved in the progression and resolution of bleomycin-induced lung fibrosis Mutant surfactant A2 proteins associated with familial pulmonary fibrosis and lung cancer induce TGF-β1 secretion.Crosstalk between TGF-β1 and complement activation augments epithelial injury in pulmonary fibrosis.Wnt coreceptor Lrp5 is a driver of idiopathic pulmonary fibrosis.Tissue-dependent consequences of Apc inactivation on proliferation and differentiation of ciliated cell progenitors via Wnt and notch signaling Conditional overexpression of TGFβ1 promotes pulmonary inflammation, apoptosis and mortality via TGFβR2 in the developing mouse lung.TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment.Blocking follistatin-like 1 attenuates bleomycin-induced pulmonary fibrosis in mice.Chitinase 1 is a biomarker for and therapeutic target in scleroderma-associated interstitial lung disease that augments TGF-β1 signaling.Angiotensin II and pulmonary fibrosis, a new twist on an old story.A novel profibrotic mechanism mediated by TGFβ-stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells Airway epithelial cells suppress T cell proliferation by an IFNγ/STAT1/TGFβ-dependent mechanism.Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate.Vagotomy attenuates bleomycin-induced pulmonary fibrosis in mice Progenitors of secondary crest myofibroblasts are developmentally committed in early lung mesoderm.Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs.C-type natriuretic peptide ameliorates pulmonary fibrosis by acting on lung fibroblasts in mice.miR-9-5p suppresses pro-fibrogenic transformation of fibroblasts and prevents organ fibrosis by targeting NOX4 and TGFBR2 Peptide-mediated inhibition of mitogen-activated protein kinase-activated protein kinase-2 ameliorates bleomycin-induced pulmonary fibrosis Transforming Growth Factor-β: Master Regulator of the Respiratory System in Health and Disease Transdifferentiation of alveolar epithelial type II to type I cells is controlled by opposing TGF-β and BMP signaling Syndecan-2 exerts antifibrotic effects by promoting caveolin-1-mediated transforming growth factor-β receptor I internalization and inhibiting transforming growth factor-β1 signaling.β-Catenin/CBP-Dependent Signaling Regulates TGF-β-Induced Epithelial to Mesenchymal Transition of Lens Epithelial Cells

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Epithelium-specific deletion of TGF-β receptor type II protects mice from bleomycin-induced pulmonary fibrosis.

http://www.wikidata.org/entity/Q34428905

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Epithelium-specific deletion o ...... in-induced pulmonary fibrosis.

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Epithelium-specific deletion o ...... in-induced pulmonary fibrosis.

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Epithelium-specific deletion o ...... in-induced pulmonary fibrosis.

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type

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Epithelium-specific deletion o ...... in-induced pulmonary fibrosis.

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Epithelium-specific deletion o ...... in-induced pulmonary fibrosis.

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Epithelium-specific deletion o ...... in-induced pulmonary fibrosis.

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Epithelium-specific deletion o ...... in-induced pulmonary fibrosis.

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Epithelium-specific deletion o ...... in-induced pulmonary fibrosis.

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Epithelium-specific deletion o ...... in-induced pulmonary fibrosis.

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Journal of Clinical Investigation

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Epithelium-specific deletion o ...... in-induced pulmonary fibrosis.

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Agnes Banfalvi

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Aimin Li

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Beiyun Zhou

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Changgong Li

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Manda Sai Krishnaveni

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Min Li

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Omid Akbari

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Parviz Minoo

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Vincent Lombardi

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Yiming Xing

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P2860

TGF-beta signal transduction

Generalized lacZ expression with the ROSA26 Cre reporter strain

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy

Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction

TGF-beta is a critical mediator of acute lung injury

Wnt5a regulates Shh and Fgf10 signaling during lung development

Differential requirements for Smad4 in TGFbeta-dependent patterning of the early mouse embryo

Mesodermal deletion of transforming growth factor-beta receptor II disrupts lung epithelial morphogenesis: cross-talk between TGF-beta and Sonic hedgehog pathways

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277-287

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10.1172/JCI42090

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1

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121

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2010-12-06T00:00:00Z

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21135509

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pulmonary fibrosis

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3007138

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