New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica.
about
Concise total synthesis of (+/-)-salinosporamide A, (+/-)-cinnabaramide A, and derivatives via a bis-cyclization process: implications for a biosynthetic pathway?Discovery and characterization of a marine bacterial SAM-dependent chlorinaseGenomics against flatulenceMarine actinomycetes: a new source of compounds against the human malaria parasiteA novel alkaloid from marine-derived actinomycete Streptomyces xinghaiensis with broad-spectrum antibacterial and cytotoxic activitiesA new family of iron-dependent halogenases acts on freestanding substrates.New C-19-modified geldanamycin derivatives: synthesis, antitumor activities, and physical properties study.Marinisporolides, polyene-polyol macrolides from a marine actinomycete of the new genus MarinisporaProteasome inhibitors in glioblastomaDiscovery and development of the anticancer agent salinosporamide A (NPI-0052).Natural products from mangrove actinomycetes.Marine Rare Actinobacteria: Isolation, Characterization, and Strategies for Harnessing Bioactive Compounds.Characterization of non-heme iron aliphatic halogenase WelO5* fromHapalosiphon welwitschiiIC-52-3: Identification of a minimal protein sequence motif that confers enzymatic chlorination specificity in the biosynthesis of welwitindolelinones.Generating a generation of proteasome inhibitors: from microbial fermentation to total synthesis of salinosporamide a (marizomib) and other salinosporamidesAntibiotic producing potentials of three freshwater actinomycetes isolated from the Eastern Cape Province of South Africa.Total synthesis of sporolide B and 9-epi-sporolide B.Salinosporamide natural products: Potent 20 S proteasome inhibitors as promising cancer chemotherapeutics.Functional gene-guided discovery of type II polyketides from culturable actinomycetes associated with soft coral Scleronephthya spDirected evolution of RebH for site-selective halogenation of large biologically active molecules.The marine actinomycete genus Salinispora: a model organism for secondary metabolite discoveryAdvances in and applications of proteasome inhibitorsProteasome regulator marizomib (NPI-0052) exhibits prolonged inhibition, attenuated efflux, and greater cytotoxicity than its reversible analogsEvolution of secondary metabolite genes in three closely related marine actinomycete speciesTaxonomy, Physiology, and Natural Products of Actinobacteria.Using Molecular Networking for Microbial Secondary Metabolite Bioprospecting.The occurrence of bioactive micromonosporae in aquatic habitats of the Sunshine Coast in Australia.Azamerone, a terpenoid phthalazinone from a marine-derived bacterium related to the genus Streptomyces (Actinomycetales).Marizomib, a proteasome inhibitor for all seasons: preclinical profile and a framework for clinical trialsActinomycetes for marine drug discovery isolated from mangrove soils and plants in China.Biosynthesis of salinosporamides from alpha,beta-unsaturated fatty acids: implications for extending polyketide synthase diversity.Antitumor compounds from marine actinomycetes.Development of novel drugs from marine surface associated microorganisms.Exploitation of phage battery in the search for bioactive actinomycetes.Exploiting nature's rich source of proteasome inhibitors as starting points in drug development.Synthesis and pharmacology of proteasome inhibitors.Antibacterial, Anticancer and Neuroprotective Activities of Rare Actinobacteria from Mangrove Forest Soils.Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse.Actinobacteria and Myxobacteria-Two of the Most Important Bacterial Resources for Novel Antibiotics.Natural Products and the Gene Cluster Revolution.Recent advances in the Overman rearrangement: synthesis of natural products and valuable compounds.
P2860
Q24642621-8BF5C2A1-65CB-4C7C-ABC2-D3C936410FEEQ24652817-CBEF4A97-843B-409C-9381-E92D0B5BDED2Q27481054-AAFDA569-CD0E-4539-8085-2221245ECC25Q28472855-C12D1065-4455-4DA1-8D5C-BFFD6A0B143FQ28533960-1DD241EB-0CCC-4E26-B83E-DE52B3F9FD2FQ30851050-43750F03-02AD-4A68-9B3A-62BD731CFCF9Q31060049-9AB6790A-11E6-4DEF-A4B5-249A00CD69D1Q33398626-3827715D-BD8D-453F-8852-C298F89EDD14Q33598931-788526CC-D805-4A86-A457-691CEDEC3C5BQ33622960-27FEBFE5-71DE-4E8E-82D5-94FC74F92CDAQ33736692-D114FF94-5C80-431B-9648-FFF6466420A0Q33799744-13ED6E55-3A26-4B88-8620-3BD225D7308BQ33824234-4C74ECB7-29DD-4DCA-8775-E615BB99D3C8Q33836952-CD947583-9225-4FC4-9F67-E176949DB33DQ34061889-76CBF692-F65B-401C-9C03-9F2DFA590E08Q34100015-95968756-C2FE-45C0-B8F5-DCC4155B4FF2Q34142223-1A6FEAC0-A2E6-4B2D-B9BE-6AF0A78F34B2Q34374793-F13DAA10-05D6-478E-83B0-D28224C2DF95Q34462524-83E6B00A-51E8-412E-BA11-89A18BCBD06FQ34465208-BC6F316D-5A0B-4AFC-B6E9-EE2030F1324EQ34594744-B3374625-9840-4131-8F40-CABBE807F5CFQ34868045-07743E77-ADBF-40C3-87B2-A8A163699E70Q35362075-F10DA37E-7FA4-4287-B583-6FF44A2B67D6Q36457919-52424AAE-1202-4C19-BA60-D35D4D92CBC4Q36741597-6ECE123B-3DD7-4648-A1E6-9D3DB2AC9340Q36851585-B533C655-F85C-4C07-8169-3AF690A81AD6Q37001071-534508B1-D04C-4D93-98C4-6ED694F3D7F9Q37017342-6783C92B-DCB6-4461-A3DD-D296F5573F91Q37153394-B03424EC-C3BE-4A37-86EA-ECA632E0C6C2Q37331323-C8F95B43-8747-4D01-BF39-30D8D29E648CQ37549963-F4960409-51AD-4780-ABAD-16E936690430Q37735703-4F077251-2BB6-43C3-BDB6-D81CBDA0B246Q37814178-46110205-C31D-443A-99D7-4F059A784F2BQ37951013-78D7D4D8-0B75-4A80-B002-8FF65C6B2EC5Q38092777-08CCBB12-53AF-4D90-AB7F-D04299F3AB33Q38700414-43693205-ADD8-44F6-B1BC-262EB222D61FQ38768051-E8BB71C9-207A-4843-B2F1-DD1F656A77D4Q38814785-AD5E9F04-BA9C-40E3-95CB-C4536BB0F920Q38918786-C77555A4-5CB4-4DAD-848A-C91DB5C148DBQ39168195-DFD2D70D-2EA7-4107-AF15-2AACF7179E12
P2860
New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica.
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica.
@ast
New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica.
@en
New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica.
@nl
type
label
New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica.
@ast
New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica.
@en
New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica.
@nl
prefLabel
New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica.
@ast
New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica.
@en
New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica.
@nl
P2093
P356
P1476
New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica.
@en
P2093
Christopher A Kauffman
Greg O Buchanan
Paul R Jensen
Philip G Williams
Robert H Feling
William Fenical
P304
P356
10.1021/JO050511+
P407
P577
2005-08-01T00:00:00Z