Genomic discovery of potent chromatin insulators for human gene therapy. - Test2 - elhamkhani - TriplyDB

Genomic discovery of potent chromatin insulators for human gene therapy.

Genomic discovery of potent chromatin insulators for human gene therapy.

http://www.wikidata.org/entity/Q34457712

about

Contribution of Topological Domains and Loop Formation to 3D Chromatin Organization β-thalassemias: paradigmatic diseases for scientific discoveries and development of innovative therapies The cancer-associated CTCFL/BORIS protein targets multiple classes of genomic repeats, with a distinct binding and functional preference for humanoid-specific SVA transposable elements Functional assessment of CTCF sites at cytokine-sensing mammary enhancers using CRISPR/Cas9 gene editing in mice Insulated Neighborhoods: Structural and Functional Units of Mammalian Gene Control.Functional validation of a constitutive autonomous silencer element.Non-viral therapeutic approaches to ocular diseases: An overview and future directions Genetic treatment of a molecular disorder: gene therapy approaches to sickle cell disease.Evaluating the Safety of Retroviral Vectors Based on Insertional Oncogene Activation and Blocked Differentiation in Cultured Thymocytes.Enhancer Sharing Promotes Neighborhoods of Transcriptional Regulation Across Eukaryotes.Evidence for the in vivo safety of insulated foamy viral vectors Cell and Gene Therapy for the Beta-Thalassemias: Advances and Prospects.Viral Vectors: The Road to Reducing Genotoxicity.Insulated Foamy Viral Vectors.Retroviral vector interactions with hematopoietic cells.Gene Therapy for β-Hemoglobinopathies.Foamy Virus Vector Carries a Strong Insulator in Its Long Terminal Repeat Which Reduces Its Genotoxic Potential.Engineering insect-free cereals.Insulators to Improve the Safety of Retroviral Vectors for HIV Gene Therapy.Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism.Non-Primate Lentiviral Vectors and Their Applications in Gene Therapy for Ocular Disorders.

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Genomic discovery of potent chromatin insulators for human gene therapy.

http://www.wikidata.org/entity/Q34457712

description

2015 nî lūn-bûn

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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2015 թվականի հունվարին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

@zh-hant

2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Genomic discovery of potent chromatin insulators for human gene therapy.

@ast

Genomic discovery of potent chromatin insulators for human gene therapy.

@en

Genomic discovery of potent chromatin insulators for human gene therapy.

@nl

type

label

Genomic discovery of potent chromatin insulators for human gene therapy.

@ast

Genomic discovery of potent chromatin insulators for human gene therapy.

@en

Genomic discovery of potent chromatin insulators for human gene therapy.

@nl

prefLabel

Genomic discovery of potent chromatin insulators for human gene therapy.

@ast

Genomic discovery of potent chromatin insulators for human gene therapy.

@en

Genomic discovery of potent chromatin insulators for human gene therapy.

@nl

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Nature Biotechnology

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Genomic discovery of potent chromatin insulators for human gene therapy.

@en

P2093

Chao-Zhong Song

http://www.w3.org/2001/XMLSchema#string

David W Emery

http://www.w3.org/2001/XMLSchema#string

George Stamatoyannopoulos

http://www.w3.org/2001/XMLSchema#string

Hao Wang

http://www.w3.org/2001/XMLSchema#string

Heyuan Qi

http://www.w3.org/2001/XMLSchema#string

Matthew T Maurano

http://www.w3.org/2001/XMLSchema#string

Mingdong Liu

http://www.w3.org/2001/XMLSchema#string

Patrick A Navas

http://www.w3.org/2001/XMLSchema#string

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Critical DNA binding interactions of the insulator protein CTCF: a small number of zinc fingers mediate strong binding, and a single finger-DNA interaction controls binding at imprinted loci

The insulation of genes from external enhancers and silencing chromatin.

The accessible chromatin landscape of the human genome

Widespread plasticity in CTCF occupancy linked to DNA methylation

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

CTCF: master weaver of the genome

Analysis of the vertebrate insulator protein CTCF-binding sites in the human genome

The protein CTCF is required for the enhancer blocking activity of vertebrate insulators

CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease

Insulators: exploiting transcriptional and epigenetic mechanisms

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10.1038/NBT.3062

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2

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33

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John A Stamatoyannopoulos

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2015-01-12T00:00:00Z

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25580597

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