Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites. - Test2 - elhamkhani - TriplyDB

Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.

Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.

http://www.wikidata.org/entity/Q34474077

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Illuminating Spatial and Temporal Organization of Protein Interaction Networks by Mass Spectrometry-Based Proteomics The Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and Repair Cullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resection The SWI/SNF ATP-dependent nucleosome remodeler promotes resection initiation at a DNA double-strand break in yeast.Mutational phospho-mimicry reveals a regulatory role for the XRCC4 and XLF C-terminal tails in modulating DNA bridging during classical non-homologous end joining Non-homologous end joining: Common interaction sites and exchange of multiple factors in the DNA repair process.Cloning, localization and focus formation at DNA damage sites of canine Ku70.Phosphorylation of Ku dictates DNA double-strand break (DSB) repair pathway choice in S phase Targeting DNA Repair in Cancer: Beyond PARP Inhibitors.FBXW7 Facilitates Nonhomologous End-Joining via K63-Linked Polyubiquitylation of XRCC4.Spatiotemporal regulation of posttranslational modifications in the DNA damage response.Combinatorial Screening of Pancreatic Adenocarcinoma Reveals Sensitivity to Drug Combinations Including Bromodomain Inhibitor Plus Neddylation Inhibitor.Characterization of the mammalian family of DCN-type NEDD8 E3 ligases.MLN4924, a First-in-Class NEDD8-Activating Enzyme Inhibitor, Attenuates IFN-β Production.Ubiquitylation of Ku80 by RNF126 Promotes Completion of Nonhomologous End Joining-Mediated DNA Repair A novel alkylating agent Melflufen induces irreversible DNA damage and cytotoxicity in multiple myeloma cells NEDD8 and HDACs: promising cotargets in AML.Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks.The role of ubiquitin-dependent segregase p97 (VCP or Cdc48) in chromatin dynamics after DNA double strand breaks.FBW7 regulates DNA interstrand cross-link repair by modulating FAAP20 degradation.Ubiquitin regulates dissociation of DNA repair factors from chromatin.Cloning of canine Ku80 and its localization and accumulation at DNA damage sites.NEDDylation antagonizes ubiquitination of proliferating cell nuclear antigen and regulates the recruitment of polymerase η in response to oxidative DNA damage.How cells ensure correct repair of DNA double-strand breaks.DNA-damage-induced degradation of EXO1 exonuclease limits DNA end resection to ensure accurate DNA repair.SUMO, a small, but powerful, regulator of double-strand break repair.Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses NF2 Loss-Driven Tumorigenesis.

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P2860

Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.

http://www.wikidata.org/entity/Q34474077

description

2015 nî lūn-bûn

@nan

2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2015 թվականի ապրիլին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

name

Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.

@ast

Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.

@en

Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.

@nl

type

label

Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.

@ast

Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.

@en

Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.

@nl

prefLabel

Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.

@ast

Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.

@en

Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.

@nl

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J.CELREP.2015.03.058

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Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites

@en

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Carlos le Sage

http://www.w3.org/2001/XMLSchema#string

Jessica S Brown

http://www.w3.org/2001/XMLSchema#string

Matylda Sczaniecka-Clift

http://www.w3.org/2001/XMLSchema#string

Natalia Lukashchuk

http://www.w3.org/2001/XMLSchema#string

Sébastien Britton

http://www.w3.org/2001/XMLSchema#string

P2860

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

The E3 ligase RNF8 regulates KU80 removal and NHEJ repair

APLF promotes the assembly and activity of non-homologous end joining protein complexes

The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae

DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair

Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation

E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification

Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway

The DNA-damage response in human biology and disease

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

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704-714

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scholarly article

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10.1016/J.CELREP.2015.03.058

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5

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11

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Stephen P Jackson

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2015-04-23T00:00:00Z

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25921528

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4431666

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