The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae
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The NEDD8 modification pathway in plantsCullin-RING ubiquitin ligases: global regulation and activation cyclesSOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomasStructural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugationE2-RING expansion of the NEDD8 cascade confers specificity to cullin modificationSCCRO (DCUN1D1) is an essential component of the E3 complex for neddylationRapid E2-E3 assembly and disassembly enable processive ubiquitylation of cullin-RING ubiquitin ligase substratesTRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexesSCCRO promotes glioma formation and malignant progression in miceThe structure and regulation of Cullin 2 based E3 ubiquitin ligases and their biological functionsThe Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and RepairInhibition of NEDD8-conjugation pathway by novel molecules: potential approaches to anticancer therapyBuilding and remodelling Cullin-RING E3 ubiquitin ligasesStructural basis for the function of DCN-1 in protein NeddylationA Dual E3 Mechanism for Rub1 Ligation to Cdc53N-Terminal Acetylation Acts as an Avidity Enhancer Within an Interconnected Multiprotein ComplexStructural Conservation of Distinctive N-terminal Acetylation-Dependent Interactions across a Family of Mammalian NEDD8 Ligation EnzymesCullin neddylation and substrate-adaptors counteract SCF inhibition by the CAND1-like protein Lag2 in Saccharomyces cerevisiae.A longevity protein, Lag2, interacts with SCF complex and regulates SCF functionUbiquitylation, neddylation and the DNA damage responseTranscriptional profiling of rats subjected to gestational undernourishment: implications for the developmental variations in metabolic traitsInhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3GAggresome-forming TTRAP mediates pro-apoptotic properties of Parkinson's disease-associated DJ-1 missense mutations.Ubiquitin, hormones and biotic stress in plantsDevelopment and validation of a method for profiling post-translational modification activities using protein microarrays.Fission yeast neddylation ligase Dcn1 facilitates cohesin cleavage and chromosome segregation at anaphase.The essential functions of NEDD8 are mediated via distinct surface regions, and not by polyneddylation in Schizosaccharomyces pombe.Structural and functional insights to ubiquitin-like protein conjugation.Rbx1 flexible linker facilitates cullin-RING ligase function before neddylation and after deneddylation.Protein neddylation: beyond cullin-RING ligases.Twists and turns in ubiquitin-like protein conjugation cascades.UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1α accumulation.Neddylation dysfunction in Alzheimer's disease.Oncogenic function of SCCRO5/DCUN1D5 requires its Neddylation E3 activity and nuclear localization.Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapyAXR1-ECR1 and AXL1-ECR1 heterodimeric RUB-activating enzymes diverge in function in Arabidopsis thalianaComposition, roles, and regulation of cullin-based ubiquitin e3 ligases.SCCRO3 (DCUN1D3) antagonizes the neddylation and oncogenic activity of SCCRO (DCUN1D1)The ubiquitin-associated (UBA) domain of SCCRO/DCUN1D1 protein serves as a feedback regulator of biochemical and oncogenic activity.
P2860
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P248
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P2860
The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The conserved protein DCN-1/Dc ...... n C. elegans and S. cerevisiae
@ast
The conserved protein DCN-1/Dc ...... n C. elegans and S. cerevisiae
@en
The conserved protein DCN-1/Dc ...... n C. elegans and S. cerevisiae
@en-gb
The conserved protein DCN-1/Dc ...... n C. elegans and S. cerevisiae
@nl
type
label
The conserved protein DCN-1/Dc ...... n C. elegans and S. cerevisiae
@ast
The conserved protein DCN-1/Dc ...... n C. elegans and S. cerevisiae
@en
The conserved protein DCN-1/Dc ...... n C. elegans and S. cerevisiae
@en-gb
The conserved protein DCN-1/Dc ...... n C. elegans and S. cerevisiae
@nl
prefLabel
The conserved protein DCN-1/Dc ...... n C. elegans and S. cerevisiae
@ast
The conserved protein DCN-1/Dc ...... n C. elegans and S. cerevisiae
@en
The conserved protein DCN-1/Dc ...... n C. elegans and S. cerevisiae
@en-gb
The conserved protein DCN-1/Dc ...... n C. elegans and S. cerevisiae
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
The conserved protein DCN-1/Dc ...... n C. elegans and S. cerevisiae
@en
P2093
Bruce Bowerman
Fabian Rudolf
Kay Hofmann
Nurhan Ozlü
Sean M O'Rourke
P2860
P2888
P304
P3181
P356
10.1038/NATURE03662
P407
P577
2005-06-01T00:00:00Z
P5875
P6179
1044667523