Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers. - Test2 - elhamkhani - TriplyDB

Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers.

Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers.

http://www.wikidata.org/entity/Q34504751

about

Gene aberrations for precision medicine against lung adenocarcinoma Allosteric Activation of Ubiquitin-Specific Proteases by β-Propeller Proteins UAF1 and WDR20 Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas.Systematic mapping of functional enhancer-promoter connections with CRISPR interference.MYC Deregulation in Primary Human Cancers.Integrative analysis of genomic alterations in triple-negative breast cancer in association with homologous recombination deficiency.Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking.Insertions and Deletions Target Lineage-Defining Genes in Human Cancers.Scalable Design of Paired CRISPR Guide RNAs for Genomic Deletion Tissue-specific tumorigenesis: context matters.Functional interrogation of non-coding DNA through CRISPR genome editing.Epigenomic annotation of noncoding mutations identifies mutated pathways in primary liver cancer MYC activation and BCL2L11 silencing by a tumour virus through the large-scale reconfiguration of enhancer-promoter hubs.Epigenetic remodeling regulates transcriptional changes between ovarian cancer and benign precursors Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity.Hotspots of aberrant enhancer activity punctuate the colorectal cancer epigenome.Small genomic insertions form enhancers that misregulate oncogenes TMPRSS2-ERG fusion co-opts master transcription factors and activates NOTCH signaling in primary prostate cancer.Nasopharyngeal carcinoma super-enhancer-driven ETV6 correlates with prognosis.Enhancer deregulation in cancer and other diseases.Emergence of the Noncoding Cancer Genome: A Target of Genetic and Epigenetic Alterations.Genomic effects of glucocorticoids.Genome-Wide Approaches to Defining Macrophage Identity and Function Transcriptional Addiction in Cancer.MYC Modulation around the CDK2/p27/SKP2 Axis Super-Enhancer-Driven Transcriptional Dependencies in Cancer.Multiplexed Gene Editing and Protein Overexpression Using a Tobacco mosaic virus Viral Vector.A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers.MUC1-C activates EZH2 expression and function in human cancer cells.FOXA and master transcription factors recruit Mediator and Cohesin to the core transcriptional regulatory circuitry of cancer cells Common nonmutational NOTCH1 activation in chronic lymphocytic leukemia.Gene signature driving invasive mucinous adenocarcinoma of the lung.Global Inhibition with Specific Activation: How p53 and MYC Redistribute the Transcriptome in the DNA Double-Strand Break Response.Clinical study of genomic drivers in pancreatic ductal adenocarcinoma.CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine.Super enhancer associated RAI14 is a new potential biomarker in lung adenocarcinoma.CRISPR-based strategies for studying regulatory elements and chromatin structure in mammalian gene control.Somatic Superenhancer Duplications and Hotspot Mutations Lead to Oncogenic Activation of the KLF5 Transcription Factor.Whole Genome Sequencing Analysis for Cancer Genomics and Precision Medicine.Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling.

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Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers.

http://www.wikidata.org/entity/Q34504751

description

2015 nî lūn-bûn

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2015 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Identification of focally ampl ...... s in human epithelial cancers.

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Identification of focally ampl ...... s in human epithelial cancers.

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Identification of focally ampl ...... s in human epithelial cancers.

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type

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Identification of focally ampl ...... s in human epithelial cancers.

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Identification of focally ampl ...... s in human epithelial cancers.

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Identification of focally ampl ...... s in human epithelial cancers.

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prefLabel

Identification of focally ampl ...... s in human epithelial cancers.

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Identification of focally ampl ...... s in human epithelial cancers.

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Identification of focally ampl ...... s in human epithelial cancers.

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Nature Genetics

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Identification of focally ampl ...... s in human epithelial cancers.

@en

P2093

Andrew D Cherniack

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Hideo Watanabe

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Joshua M Francis

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Peter S Choi

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Xiaoyang Zhang

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P2860

Model-based analysis of ChIP-Seq (MACS)

An integrated encyclopedia of DNA elements in the human genome

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

The accessible chromatin landscape of the human genome

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

Histone H3K27ac separates active from poised enhancers and predicts developmental state

Complex landscapes of somatic rearrangement in human breast cancer genomes.

Mediator and cohesin connect gene expression and chromatin architecture

FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription

Characterizing the cancer genome in lung adenocarcinoma.

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176-182

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10.1038/NG.3470

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2

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48

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Marcin Imielinski

Matthew Meyerson

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2015-12-14T00:00:00Z

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26656844

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4857881

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