Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner. - Test2 - elhamkhani - TriplyDB

Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner.

Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner.

http://www.wikidata.org/entity/Q34568352

about

RNF185 is a novel E3 ligase of endoplasmic reticulum-associated degradation (ERAD) that targets cystic fibrosis transmembrane conductance regulator (CFTR)The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology An apicoplast localized ubiquitylation system is required for the import of nuclear-encoded plastid proteins Induction of Herpud1 expression by ER stress is regulated by Nrf1 Derlin-1 deficiency is embryonic lethal, Derlin-3 deficiency appears normal, and Herp deficiency is intolerant to glucose load and ischemia in mice ERAD defects and the HFE-H63D variant are associated with increased risk of liver damages in Alpha 1-Antitrypsin Deficiency Ube2g2-gp78-mediated HERP polyubiquitylation is involved in ER stress recovery Misfolded proteins induce aggregation of the lectin Yos9.Expression of endoplasmic reticulum stress-related factors in the retinas of diabetic rats Dysfunctional pro-ceramide, ER stress, and insulin/IGF signaling networks with progression of Alzheimer's disease The NF-κB-dependent and -independent transcriptome and chromatin landscapes of human coronavirus 229E-infected cells.HERPUD1 protects against oxidative stress-induced apoptosis through downregulation of the inositol 1,4,5-trisphosphate receptor Crystal structure of SEL1L: Insight into the roles of SLR motifs in ERAD pathway.Herp depletion arrests the S phase of the cell cycle and increases estradiol synthesis in mouse granulosa cells.Derlin2 protein facilitates HRD1-mediated retro-translocation of sonic hedgehog at the endoplasmic reticulum.Role of HERP and a HERP-related protein in HRD1-dependent protein degradation at the endoplasmic reticulum.Endoplasmic reticulum and the unfolded protein response: dynamics and metabolic integration Specificity and regulation of the endoplasmic reticulum-associated degradation machinery.The role of the unfolded protein response in diabetes mellitus.Herp coordinates compartmentalization and recruitment of HRD1 and misfolded proteins for ERAD.Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication.HERP Binds TBK1 To Activate Innate Immunity and Repress Virus Replication in Response to Endoplasmic Reticulum Stress.ER Stress Proteins in Autoimmune and Inflammatory Diseases Characterization of protein complexes of the endoplasmic reticulum-associated degradation E3 ubiquitin ligase Hrd1.Conserved cytoplasmic domains promote Hrd1 ubiquitin ligase complex formation for ER-associated degradation (ERAD).A novel mechanism regulating insulin secretion involving Herpud1 in mice.

P2860

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P2860

Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner.

http://www.wikidata.org/entity/Q34568352

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner.

@ast

Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner.

@en

Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner.

@nl

type

label

Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner.

@ast

Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner.

@en

Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner.

@nl

prefLabel

Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner.

@ast

Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner.

@en

Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner.

@nl

P1433

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Q34568352-EA276040-4FAF-45D0-9AE0-3C1753C768B1

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P932

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P356

JBC.M110.134551

P1433

Journal of Biological Chemistry

P1476

Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner.

@en

P2093

Melanie Kny

http://www.w3.org/2001/XMLSchema#string

Michael Seeger

http://www.w3.org/2001/XMLSchema#string

Rasmus Hartmann-Petersen

http://www.w3.org/2001/XMLSchema#string

Sybille Standera

http://www.w3.org/2001/XMLSchema#string

P2860

The novel MMS-inducible gene Mif1/KIAA0025 is a target of the unfolded protein response pathway

Herp, a new ubiquitin-like membrane protein induced by endoplasmic reticulum stress

A membrane protein required for dislocation of misfolded proteins from the ER

A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum

OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD

Herp enhances ER-associated protein degradation by recruiting ubiquilins

PRKCSH/80K-H, the protein mutated in polycystic liver disease, protects polycystin-2/TRPP2 against HERP-mediated degradation

Human HRD1 protects against ER stress-induced apoptosis through ER-associated degradation

ER stress differentially regulates the stabilities of ERAD ubiquitin ligases and their substrates

P304

5151-5156

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scholarly article

P356

10.1074/JBC.M110.134551

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P407

P433

7

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P478

286

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P50

Peter-Michael Kloetzel

P577

2010-12-13T00:00:00Z

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P698

21149444

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P921

P932

3037627

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