Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals. - Test2 - elhamkhani - TriplyDB

Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals.

Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals.

http://www.wikidata.org/entity/Q34574100

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The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction Therapeutic efficacy of monthly subcutaneous injection of daclizumab in relapsing multiple sclerosis Inhibition of G-protein βγ signaling enhances T cell receptor-stimulated interleukin 2 transcription in CD4+ T helper cells A novel function of IL-2: chemokine/chemoattractant/retention receptor genes induction in Th subsets for skin and lung inflammation.Negative feedback regulation of T cells via interleukin-2 and FOXP3 reciprocity.Baseline levels of influenza-specific CD4 memory T-cells affect T-cell responses to influenza vaccines.Loss of Jak2 selectively suppresses DC-mediated innate immune response and protects mice from lethal dose of LPS-induced septic shock.Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection Diversity and plasticity of Th cell types predicted from regulatory network modelling.Constitutively active Stat5b in CD4+ T cells inhibits graft-versus-host disease lethality associated with increased regulatory T-cell potency and decreased T effector cell responses.IL-12 family cytokines: immunological playmakers Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550).Soluble IL-2Rα (sCD25) exacerbates autoimmunity and enhances the development of Th17 responses in mice Activated human T cells secrete exosomes that participate in IL-2 mediated immune response signaling.CD4 memory T cells divide poorly in response to antigen because of their cytokine profile Using an adaptive gene network model for self-organizing multicellular behavior.Association of IL-27 gene three polymorphisms with Crohn's disease susceptibility in a Chinese Han population Induction of PP2A Bβ, a regulator of IL-2 deprivation-induced T-cell apoptosis, is deficient in systemic lupus erythematosus.STAT3 protein promotes T-cell survival and inhibits interleukin-2 production through up-regulation of Class O Forkhead transcription factors.An artificial antigen-presenting cell with paracrine delivery of IL-2 impacts the magnitude and direction of the T cell response.CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice Vaccine-induced antibody isotypes are skewed by impaired CD4 T cell and invariant NKT cell effector responses in MyD88-deficient mice.Microbe-dendritic cell dialog controls regulatory T-cell fate.The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2 Novel IL27p28/IL12p40 cytokine suppressed experimental autoimmune uveitis by inhibiting autoreactive Th1/Th17 cells and promoting expansion of regulatory T cells Aiolos promotes TH17 differentiation by directly silencing Il2 expression Biphasic regulation of Il2 transcription in CD4+ T cells: roles for TNF-alpha receptor signaling and chromatin structure.Inhibition of G-Protein βγ Signaling Decreases Levels of Messenger RNAs Encoding Proinflammatory Cytokines in T Cell Receptor-Stimulated CD4(+) T Helper Cells.Genomic dissection of the cytokine-controlled STAT5 signaling network in liver Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions.In vivo suppression of naive CD4 T cell responses by IL-2- and antigen-stimulated T lymphocytes in the absence of APC competition.Production of interleukin-27 by human neutrophils regulates their function during bacterial infection.IL-2 coordinates IL-2-producing and regulatory T cell interplay.Differential cytokine sensitivities of STAT5-dependent enhancers rely on Stat5 autoregulation.T cells translate individual, quantal activation into collective, analog cytokine responses via time-integrated feedbacks.Erythropoietin receptor response circuits Soluble IL-2RA levels in multiple sclerosis subjects and the effect of soluble IL-2RA on immune responses Astragaloside II triggers T cell activation through regulation of CD45 protein tyrosine phosphatase activity

P2860

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P2860

Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals.

http://www.wikidata.org/entity/Q34574100

description

2007 nî lūn-bûn

@nan

2007 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2007年の論文

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2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

Helper T cell IL-2 production ...... AT-dependent cytokine signals.

@ast

Helper T cell IL-2 production ...... AT-dependent cytokine signals.

@en

Helper T cell IL-2 production ...... AT-dependent cytokine signals.

@nl

type

label

Helper T cell IL-2 production ...... AT-dependent cytokine signals.

@ast

Helper T cell IL-2 production ...... AT-dependent cytokine signals.

@en

Helper T cell IL-2 production ...... AT-dependent cytokine signals.

@nl

prefLabel

Helper T cell IL-2 production ...... AT-dependent cytokine signals.

@ast

Helper T cell IL-2 production ...... AT-dependent cytokine signals.

@en

Helper T cell IL-2 production ...... AT-dependent cytokine signals.

@nl

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P1433

Journal of Experimental Medicine

P1476

Helper T cell IL-2 production ...... TAT-dependent cytokine signals

@en

P2093

Christopher A Hunter

http://www.w3.org/2001/XMLSchema#string

Cristina M Tato

http://www.w3.org/2001/XMLSchema#string

Jason S Stumhofer

http://www.w3.org/2001/XMLSchema#string

John J O'Shea

http://www.w3.org/2001/XMLSchema#string

Yongzhi K Cui

http://www.w3.org/2001/XMLSchema#string

Zhengju Yao

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P2860

Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells

The B7 family revisited

Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy.

Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer.

Stat5a/b are essential for normal lymphoid development and differentiation.

Cytokines and immunodeficiency diseases.

Tolerance, not immunity, crucially depends on IL-2.

IL-7: maintaining T-cell memory and achieving homeostasis.

New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions.

Control of biologically active interleukin 2 messenger RNA formation in induced human lymphocytes.

P304

65-71

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scholarly article

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10.1084/JEM.20061198

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P407

P433

1

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P478

204

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Alejandro Villarino

Lothar Hennighausen

P577

2007-01-16T00:00:00Z

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6574555

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P698

17227909

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P932

2118423

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