Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells. - Test2 - elhamkhani - TriplyDB

Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells.

Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells.

http://www.wikidata.org/entity/Q34576335

about

The many faces of aire in central tolerance Thymic stromal lymphopoietin-activated plasmacytoid dendritic cells induce the generation of FOXP3+ regulatory T cells in human thymus Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity Transcriptional regulation by AIRE: molecular mechanisms of central tolerance T cell receptor signalling in the control of regulatory T cell differentiation and function Control of the thymic medulla and its influence on αβT-cell development Clinical features, pathogenesis, and treatment of myasthenia gravis: a supplement to the Guidelines of the German Neurological Society Induction of central tolerance by the factor Aire: molecular and epigenetic regulation The Contribution of Chemokines and Migration to the Induction of Central Tolerance in the Thymus Exosomes in the Thymus: Antigen Transfer and Vesicles Thymic Crosstalk Coordinates Medulla Organization and T-Cell Tolerance Induction Ovarian autoimmune disease: clinical concepts and animal models Stromal cell-based immunotherapy in transplantation Regulation of nuclear factor-κB in autoimmunity Trauma equals danger--damage control by the immune system Regulatory cells and transplantation tolerance New allogeneic hematopoietic stem cell transplantation method: hematopoietic stem cell transplantation plus thymus transplantation for intractable diseases Organ-specific and memory treg cells: specificity, development, function, and maintenance Regulatory T lymphocytes CD4(+): current issues The importance of regulatory T-cell heterogeneity in maintaining self-tolerance CCR4 promotes medullary entry and thymocyte-dendritic cell interactions required for central tolerance.Antigen recognition by autoreactive CD4⁺ thymocytes drives homeostasis of the thymic medulla Identification of novel thymic epithelial cell subsets whose differentiation is regulated by RANKL and Traf6 Development of Auto Antigen-specific Regulatory T Cells for Diabetes Immunotherapy Development of thymic Foxp3(+) regulatory T cells: TGF-β matters Antigen Presentation, Autoantigens, and Immune Regulation in Multiple Sclerosis and Other Autoimmune Diseases TCR signaling to NF-κB and mTORC1: Expanding roles of the CARMA1 complex Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance Differential requirement for CCR4 in the maintenance but not establishment of the invariant Vγ5(+) dendritic epidermal T-cell pool Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see)Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction Regulation of T-cell Tolerance by Lymphatic Endothelial Cells.Uterine DCs are crucial for decidua formation during embryo implantation in mice.Conserved and divergent aspects of human T-cell development and migration in humanized mice Once a Treg, always a Treg?Mechanisms of self-nonself discrimination and possible clinical relevance.Affinity-based selection of regulatory T cells occurs independent of agonist-mediated induction of Foxp3 expression The role of T-cell receptor recognition of peptide:MHC complexes in the formation and activity of Foxp3⁺ regulatory T cells.Transplantation of Donor-Origin Mouse Embryonic Stem Cell-Derived Thymic Epithelial Progenitors Prevents the Development of Chronic Graft-versus-Host Disease in Mice.Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells.

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Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells.

http://www.wikidata.org/entity/Q34576335

description

2007 nî lūn-bûn

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2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2007 թվականի փետրվարին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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Selection of Foxp3+ regulatory ...... llary thymic epithelial cells.

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Nature Immunology

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Selection of Foxp3+ regulatory ...... llary thymic epithelial cells.

@en

P2093

Antonius Rolink

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Elisabeth H Vollmann

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Jan Emmerich

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Katharina Aschenbrenner

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Lee Kim Swee

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Louise M D'Cruz

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Ludger Klein

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Maria Hinterberger

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P2860

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

Projection of an immunological self shadow within the thymus by the aire protein

Aire regulates negative selection of organ-specific T cells

Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus

Central tolerance: learning self-control in the thymus

Dependence of self-tolerance on TRAF6-directed development of thymic stroma

An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires

Several different cell surface molecules control negative selection of medullary thymocytes

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

Delayed functional maturation of natural regulatory T cells in the medulla of postnatal thymus: role of TSLP.

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351-358

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10.1038/NI1444

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4

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8

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2007-02-25T00:00:00Z

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6483251

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1021477511

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17322887

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