XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region. - Test2 - elhamkhani - TriplyDB

XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region.

XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region.

http://www.wikidata.org/entity/Q34582737

about

Dissecting the nanoscale distributions and functions of microtubule-end-binding proteins EB1 and ch-TOG in interphase HeLa cells A cryptic TOG domain with a distinct architecture underlies CLASP-dependent bipolar spindle formation CLASP2 Has Two Distinct TOG Domains That Contribute Differently to Microtubule Dynamics Coordination of adjacent domains mediates TACC3-ch-TOG-clathrin assembly and mitotic spindle binding Ahead of the Curve: New Insights into Microtubule Dynamics MAPping the Ndc80 loop in cancer: A possible link between Ndc80/Hec1 overproduction and cancer formation Lessons from in vitro reconstitution analyses of plant microtubule-associated proteins The KLP-7 Residue S546 Is a Putative Aurora Kinase Site Required for Microtubule Regulation at the Centrosome in C. elegans TOG Proteins Are Spatially Regulated by Rac-GSK3β to Control Interphase Microtubule Dynamics Alp7/TACC-Alp14/TOG generates long-lived, fast-growing MTs by an unconventional mechanism.A TOG: -tubulin Complex Structure Reveals Conformation-Based Mechanisms for a Microtubule Polymerase The XMAP215 family drives microtubule polymerization using a structurally diverse TOG array A tethered delivery mechanism explains the catalytic action of a microtubule polymerase Kinesin Kip2 enhances microtubule growth in vitro through length-dependent feedback on polymerization and catastrophe.Synergy between XMAP215 and EB1 increases microtubule growth rates to physiological levels Crescerin uses a TOG domain array to regulate microtubules in the primary cilium Conditional knockout of tumor overexpressed gene in mouse neurons affects RNA granule assembly, granule translation, LTP and short term habituation.Fission yeast Alp14 is a dose-dependent plus end-tracking microtubule polymerase One-step purification of assembly-competent tubulin from diverse eukaryotic sources.Growth cone-specific functions of XMAP215 in restricting microtubule dynamics and promoting axonal outgrowth Alp7/TACC recruits kinesin-8-PP1 to the Ndc80 kinetochore protein for timely mitotic progression and chromosome movement.Kinesin-5 is a microtubule polymerase.A TOGL domain specifically targets yeast CLASP to kinetochores to stabilize kinetochore microtubules.CDK-dependent phosphorylation of Alp7-Alp14 (TACC-TOG) promotes its nuclear accumulation and spindle microtubule assembly.Stu2, the budding yeast XMAP215/Dis1 homolog, promotes assembly of yeast microtubules by increasing growth rate and decreasing catastrophe frequency TACC3 is a microtubule plus end-tracking protein that promotes axon elongation and also regulates microtubule plus end dynamics in multiple embryonic cell types.The contribution of αβ-tubulin curvature to microtubule dynamics.Drosophila melanogaster mini spindles TOG3 utilizes unique structural elements to promote domain stability and maintain a TOG1- and TOG2-like tubulin-binding surface The microtubule lattice and plus-end association of Drosophila Mini spindles is spatially regulated to fine-tune microtubule dynamics.Biophysics of mitosis Microtubules in plants Emergent Properties of the Metaphase Spindle.Building the Microtubule Cytoskeleton Piece by Piece Mitotic spindle form and function The internal loop of fission yeast Ndc80 binds Alp7/TACC-Alp14/TOG and ensures proper chromosome attachment.Upregulation of colonic and hepatic tumor overexpressed gene is significantly associated with the unfavorable prognosis marker of human hepatocellular carcinoma.Centriolar CPAP/SAS-4 Imparts Slow Processive Microtubule Growth.The growth speed of microtubules with XMAP215-coated beads coupled to their ends is increased by tensile force.The microtubule plus-end-tracking protein TACC3 promotes persistent axon outgrowth and mediates responses to axon guidance signals during development.Regulation of microtubule dynamics by TOG-domain proteins XMAP215/Dis1 and CLASP.

P2860

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P2860

XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region.

http://www.wikidata.org/entity/Q34582737

description

2011 nî lūn-bûn

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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2011 թվականի հունվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

XMAP215 polymerase activity is ...... basic lattice-binding region.

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XMAP215 polymerase activity is ...... basic lattice-binding region.

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XMAP215 polymerase activity is ...... basic lattice-binding region.

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XMAP215 polymerase activity is ...... basic lattice-binding region.

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P356

PNAS.1016498108

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

XMAP215 polymerase activity is ...... basic lattice-binding region.

@en

P2093

Andrei Pozniakovsky

http://www.w3.org/2001/XMLSchema#string

Gary J Brouhard

http://www.w3.org/2001/XMLSchema#string

Jeffrey H Stear

http://www.w3.org/2001/XMLSchema#string

Simone Reber

http://www.w3.org/2001/XMLSchema#string

P2860

Structural basis of microtubule plus end tracking by XMAP215, CLIP-170, and EB1

Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex.

Crystal structure of a TOG domain: conserved features of XMAP215/Dis1-family TOG domains and implications for tubulin binding

An actin nucleation mechanism mediated by Bni1 and profilin.

The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends

Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architecture

Microtubule polymerization dynamics

Mechanism and function of formins in the control of actin assembly

TAC-1 and ZYG-9 form a complex that promotes microtubule assembly in C. elegans embryos

XMAP215 is a processive microtubule polymerase.

P304

2741-2746

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scholarly article

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10.1073/PNAS.1016498108

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7

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108

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Jonathon Howard

Anthony A. Hyman

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2011-01-31T00:00:00Z

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49799671

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21282620

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P932

3041093

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