Absence of the transcription factor CCAAT enhancer binding protein alpha results in loss of myeloid identity in bcr/abl-induced malignancy.
about
The Philadelphia chromosome in leukemogenesisGenome-Wide Identification of Basic Helix-Loop-Helix and NF-1 Motifs Underlying GR Binding Sites in Male Rat Hippocampus.miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts.Chronic myeloid leukemia: mechanisms of blastic transformationThe multifaceted functions of C/EBPα in normal and malignant haematopoiesis.The gene signature in CCAAT-enhancer-binding protein α dysfunctional acute myeloid leukemia predicts responsiveness to histone deacetylase inhibitors.High levels of the BCR/ABL oncoprotein are required for the MAPK-hnRNP-E2 dependent suppression of C/EBPalpha-driven myeloid differentiationIn Vivo Deletion of the Cebpa +37 kb Enhancer Markedly Reduces Cebpa mRNA in Myeloid Progenitors but Not in Non-Hematopoietic Tissues to Impair Granulopoiesis.Discovery and preliminary SAR of bisbenzylisoquinoline alkaloids as inducers of C/EBPαInhibitor of differentiation 1 transcription factor promotes metabolic reprogramming in hepatocellular carcinoma cells.Transcriptional dysregulation during myeloid transformation in AML.Dysregulation of the C/EBPalpha differentiation pathway in human cancer.Prognostic significance of, and gene and microRNA expression signatures associated with, CEBPA mutations in cytogenetically normal acute myeloid leukemia with high-risk molecular features: a Cancer and Leukemia Group B Study.Molecular biology of bcr-abl1-positive chronic myeloid leukemia.Is there a role for differentiating therapy in non-APL AML?BCR-ABL1 kinase-dependent alteration of mRNA metabolism: potential alternatives for therapeutic intervention.C/EBPα: critical at the origin of leukemic transformation.Initiation of MLL-rearranged AML is dependent on C/EBPαC/EBPα in normal and malignant myelopoiesis.The presence of C/EBPα and its degradation are both required for TRIB2-mediated leukaemia.Dominant-interfering C/EBPalpha stimulates primitive erythropoiesis in zebrafish.AAV-based shRNA silencing of NF-κB ameliorates muscle pathologies in mdx mice.BCR-ABL promotes neutrophil differentiation in the chronic phase of chronic myeloid leukemia by downregulating c-Jun expression.Loss of p53 induces leukemic transformation in a murine model of Jak2 V617F-driven polycythemia vera.
P2860
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P2860
Absence of the transcription factor CCAAT enhancer binding protein alpha results in loss of myeloid identity in bcr/abl-induced malignancy.
description
2006 nî lūn-bûn
@nan
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Absence of the transcription f ...... in bcr/abl-induced malignancy.
@ast
Absence of the transcription f ...... in bcr/abl-induced malignancy.
@en
Absence of the transcription f ...... in bcr/abl-induced malignancy.
@nl
type
label
Absence of the transcription f ...... in bcr/abl-induced malignancy.
@ast
Absence of the transcription f ...... in bcr/abl-induced malignancy.
@en
Absence of the transcription f ...... in bcr/abl-induced malignancy.
@nl
prefLabel
Absence of the transcription f ...... in bcr/abl-induced malignancy.
@ast
Absence of the transcription f ...... in bcr/abl-induced malignancy.
@en
Absence of the transcription f ...... in bcr/abl-induced malignancy.
@nl
P2093
P2860
P356
P1476
Absence of the transcription f ...... in bcr/abl-induced malignancy
@en
P2093
Bettina Drescher
D Gary Gilliland
Hanna S Radomska
Jeffery L Kutok
Jürgen Krauter
Katharina Wagner
Susumu Kobayashi
P2860
P304
P356
10.1073/PNAS.0508143103
P407
P577
2006-04-10T00:00:00Z