The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity
about
Regulation of chromatin architecture by the PWWP domain-containing DNA damage-responsive factor EXPAND1/MUM1Structural insights into recognition of acetylated histone ligands by the BRPF1 bromodomainHistone recognition and large-scale structural analysis of the human bromodomain familyMolecular architecture of quartet MOZ/MORF histone acetyltransferase complexesRecognition of unmodified histone H3 by the first PHD finger of bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases monocytic leukemic zinc-finger protein (MOZ) and MOZ-related factor (MORF)Open access chemical probes for epigenetic targetsMolecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1The double PHD finger domain of MOZ/MYST3 induces -helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modificationCombinatorial readout of unmodified H3R2 and acetylated H3K14 by the tandem PHD finger of MOZ reveals a regulatory mechanism for HOXA9 transcriptionA PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions.BET domain co-regulators in obesity, inflammation and cancerPhenoscape: Identifying Candidate Genes for Evolutionary Phenotypes500,000 fish phenotypes: The new informatics landscape for evolutionary and developmental biology of the vertebrate skeletonMutations in the Chromatin Regulator Gene BRPF1 Cause Syndromic Intellectual Disability and Deficient Histone AcetylationModes of developmental outgrowth and shaping of a craniofacial bone in zebrafish.Expression atlas of the multivalent epigenetic regulator Brpf1 and its requirement for survival of mouse embryos.Arabidopsis Histone Lysine Methyltransferases.Crystallization and preliminary X-ray diffraction analysis of the BRPF1 bromodomain in complex with its H2AK5ac and H4K12ac histone-peptide ligands.Evolution of the PWWP-domain encoding genes in the plant and animal lineagesKeeping it in the family: diverse histone recognition by conserved structural foldsExchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity.Bromodomain-PHD finger protein 1 is critical for leukemogenesis associated with MOZ-TIF2 fusion.Maintenance of neuronal laterality in Caenorhabditis elegans through MYST histone acetyltransferase complex components LSY-12, LSY-13 and LIN-49.Molecular insights into the recognition of N-terminal histone modifications by the BRPF1 bromodomain.The MOZ histone acetyltransferase in epigenetic signaling and disease.Deficiency of the chromatin regulator BRPF1 causes abnormal brain development.The lysine acetyltransferase activator Brpf1 governs dentate gyrus development through neural stem cells and progenitors.The chromatin regulator Brpf1 regulates embryo development and cell proliferationBivalent interaction of the PZP domain of BRPF1 with the nucleosome impacts chromatin dynamics and acetylation.The Chromatin Regulator BRPF3 Preferentially Activates the HBO1 Acetyltransferase but Is Dispensable for Mouse Development and Survival.Polycomb purification by in vivo biotinylation tagging reveals cohesin and Trithorax group proteins as interaction partners.TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replicationPerceiving the epigenetic landscape through histone readers.Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity.BRPF1 is essential for development of fetal hematopoietic stem cellsMYST family histone acetyltransferases take center stage in stem cells and development.Crosstalk between epigenetic readers regulates the MOZ/MORF HAT complexes.Transcriptional and epigenetic networks in haematological malignancy.The bromodomain interaction module.Transcription-associated histone modifications and cryptic transcription.
P2860
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P2860
The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
name
The multidomain protein Brpf1 ...... ression and segmental identity
@ast
The multidomain protein Brpf1 ...... ression and segmental identity
@en
The multidomain protein Brpf1 ...... ression and segmental identity
@nl
type
label
The multidomain protein Brpf1 ...... ression and segmental identity
@ast
The multidomain protein Brpf1 ...... ression and segmental identity
@en
The multidomain protein Brpf1 ...... ression and segmental identity
@nl
prefLabel
The multidomain protein Brpf1 ...... ression and segmental identity
@ast
The multidomain protein Brpf1 ...... ression and segmental identity
@en
The multidomain protein Brpf1 ...... ression and segmental identity
@nl
P2093
P2860
P356
P1433
P1476
The multidomain protein Brpf1 ...... ression and segmental identity
@en
P2093
Charles B Kimmel
Henry H Roehl
Justin Gage Crump
Kathrin Laue
Nikki Plaster
Robert Schneider
Tübingen 2000 Screen Consortium
P2860
P304
P356
10.1242/DEV.017160
P407
P577
2008-06-01T00:00:00Z