Is it possible to improve memory function by upregulation of the cholesterol 24S-hydroxylase (CYP46A1) in the brain?
about
Myelination, oligodendrocytes, and serious mental illness.Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology.Genetic, anatomic, and clinical determinants of human serum sterol and vitamin D levelsCholesterol in brain disease: sometimes determinant and frequently implicated.Cholesterolomics: An updateEndogenous 24S-hydroxycholesterol modulates NMDAR-mediated function in hippocampal slices.Mapping of the Allosteric Site in Cholesterol Hydroxylase CYP46A1 for Efavirenz, a Drug That Stimulates Enzyme ActivityNeuronal cholesterol metabolism increases dendritic outgrowth and synaptic markers via a concerted action of GGTase-I and Trk.Pharmacologic stimulation of cytochrome P450 46A1 and cerebral cholesterol turnover in mice.Lipid dynamics at dendritic spines.In vitro cytochrome P450 46A1 (CYP46A1) activation by neuroactive compounds.27-Hydroxycholesterol impairs neuronal glucose uptake through an IRAP/GLUT4 system dysregulation.Membrane lipid rafts and neurobiology: age-related changes in membrane lipids and loss of neuronal function.Cholesterol-metabolizing enzyme cytochrome P450 46A1 as a pharmacologic target for Alzheimer's disease.Cholesterol 24S-Hydroxylase Overexpression Inhibits the Liver X Receptor (LXR) Pathway by Activating Small Guanosine Triphosphate-Binding Proteins (sGTPases) in Neuronal Cells.
P2860
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P2860
Is it possible to improve memory function by upregulation of the cholesterol 24S-hydroxylase (CYP46A1) in the brain?
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2013 nî lūn-bûn
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2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2013 թվականի հուլիսին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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Is it possible to improve memo ...... xylase (CYP46A1) in the brain?
@ast
Is it possible to improve memo ...... xylase (CYP46A1) in the brain?
@en
Is it possible to improve memo ...... he cholesterol 24S-hydroxylase
@nl
type
label
Is it possible to improve memo ...... xylase (CYP46A1) in the brain?
@ast
Is it possible to improve memo ...... xylase (CYP46A1) in the brain?
@en
Is it possible to improve memo ...... he cholesterol 24S-hydroxylase
@nl
prefLabel
Is it possible to improve memo ...... xylase (CYP46A1) in the brain?
@ast
Is it possible to improve memo ...... xylase (CYP46A1) in the brain?
@en
Is it possible to improve memo ...... he cholesterol 24S-hydroxylase
@nl
P2093
P2860
P50
P1433
P1476
Is it possible to improve memo ...... xylase (CYP46A1) in the brain?
@en
P2093
Ahmed Saeed
Ann Båvner
Maria Olin
Marjan Shafaati
Maura Heverin
Muhammad-Al-Mustafa Ismail
Paolo Parini
P2860
P304
P356
10.1371/JOURNAL.PONE.0068534
P407
P577
2013-07-16T00:00:00Z