Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2.
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Stomach development, stem cells and diseaseHow to make an intestineInduction of cancer stem cell properties in colon cancer cells by defined factorsEpigenetic regulation of the intestinal epitheliumLoss of hepatocyte-nuclear-factor-1alpha impacts on adult mouse intestinal epithelial cell growth and cell lineages differentiationCdx2 determines the fate of postnatal intestinal endodermA regulatory network controls nephrocan expression and midgut patterningAdhesion protein VSIG1 is required for the proper differentiation of glandular gastric epitheliaThe transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytesCdx2 regulates endo-lysosomal function and epithelial cell polarityKruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epitheliumAbnormal Wnt and PI3Kinase signaling in the malformed intestine of lama5 deficient miceThe promoter for intestinal cell kinase is head-to-head with F-Box 9 and contains functional sites for TCF7L2 and FOXA factorsFunctional analysis of HOXD9 in human gliomas and glioma cancer stem cellsEctopic expression of Ptf1a induces spinal defects, urogenital defects, and anorectal malformations in Danforth's short tail mice.Mesenchymal-epithelial interactions during digestive tract development and epithelial stem cell regenerationThe intestine-specific transcription factor Cdx2 inhibits beta-catenin/TCF transcriptional activity by disrupting the beta-catenin-TCF protein complex.Obesity, rather than diet, drives epigenomic alterations in colonic epithelium resembling cancer progression.Ectopic Cdx2 expression in murine esophagus models an intermediate stage in the emergence of Barrett's esophagus.Study of FoxA pioneer factor at silent genes reveals Rfx-repressed enhancer at Cdx2 and a potential indicator of esophageal adenocarcinoma developmentDynamic patterning at the pylorus: formation of an epithelial intestine-stomach boundary in late fetal life.New insights into the development and differentiation of the human anorectal epithelia. Are there clinical consequences?TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regionsCooperation between HNF-1alpha, Cdx2, and GATA-4 in initiating an enterocytic differentiation program in a normal human intestinal epithelial progenitor cell line.Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia.Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cellModeling human gastrointestinal inflammatory diseases using microphysiological culture systems.Cdx2 levels modulate intestinal epithelium maturity and Paneth cell development.Pinin modulates expression of an intestinal homeobox gene, Cdx2, and plays an essential role for small intestinal morphogenesis.Transcriptional regulation of the intestinal nuclear bile acid farnesoid X receptor (FXR) by the caudal-related homeobox 2 (CDX2).Cdx1 and Cdx2 exhibit transcriptional specificity in the intestine.TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis.Intestine-specific transcription factor Cdx2 induces E-cadherin function by enhancing the trafficking of E-cadherin to the cell membraneDifferentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2Biology of Barrett's esophagus and esophageal adenocarcinomaVertebrate intestinal endoderm development.Dominant and context-specific control of endodermal organ allocation by Ptf1a.Loss of CDX2 expression is associated with poor prognosis in colorectal cancer patients.Epithelial BMP signaling is required for proper specification of epithelial cell lineages and gastric endocrine cells.Maternal-zygotic knockout reveals a critical role of Cdx2 in the morula to blastocyst transition.
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P2860
Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2.
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2.
@ast
Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2.
@en
Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2.
@nl
type
label
Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2.
@ast
Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2.
@en
Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2.
@nl
prefLabel
Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2.
@ast
Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2.
@en
Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2.
@nl
P2093
P2860
P1433
P1476
Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2.
@en
P2093
Klaus H Kaestner
Peter White
P2860
P304
P356
10.1016/J.DEVCEL.2009.02.010
P407
P577
2009-04-01T00:00:00Z