Remodelling of the PDE4 cAMP phosphodiesterase isoform profile upon monocyte-macrophage differentiation of human U937 cells.
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Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungsThe therapeutic profile of rolipram, PDE target and mechanism of action as a neuroprotectant following spinal cord injuryChemical informatics uncovers a new role for moexipril as a novel inhibitor of cAMP phosphodiesterase-4 (PDE4)Global expression profiling of theophylline response genes in macrophages: evidence of airway anti-inflammatory regulationPrenatal environmental exposures, epigenetics, and diseaseMorphometric Characterization of Rat and Human Alveolar Macrophage Cell Models and their Response to Amiodarone using High Content Image Analysis.Gene expression patterns in peripheral blood correlate with the extent of coronary artery disease.Elevated cyclic AMP and PDE4 inhibition induce chemokine expression in human monocyte-derived macrophagesSex-differential genetic effect of phosphodiesterase 4D (PDE4D) on carotid atherosclerosis.Apremilast, a cAMP phosphodiesterase-4 inhibitor, demonstrates anti-inflammatory activity in vitro and in a model of psoriasis.Characteristic DNA methylation profiles in peripheral blood monocytes are associated with inflammatory phenotypes of asthma.ABCD of the phosphodiesterase family: interaction and differential activity in COPDThe PDE4 inhibitor rolipram prevents NF-kappaB binding activity and proinflammatory cytokine release in human chorionic cellsRoflumilast inhibits the release of chemokines and TNF-α from human lung macrophages stimulated with lipopolysaccharide.Cyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies.Therapeutic benefits of phosphodiesterase 4B inhibition after traumatic brain injury.Traumatic Brain Injury Upregulates Phosphodiesterase Expression in the Hippocampus.Clinical potential of apremilast in the treatment of psoriatic arthritisAttenuation of TNF production and experimentally induced inflammation by PDE4 inhibitor rolipram is mediated by MAPK phosphatase-1.MEK1 binds directly to betaarrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization.Clinical and molecular genetics of the phosphodiesterases (PDEs).Cyclic nucleotides and phosphodiesterases in monocytic differentiation.Apremilast: a novel PDE4 inhibitor in the treatment of autoimmune and inflammatory diseases.Apremilast: a PDE4 inhibitor for the treatment of psoriatic arthritis.Phosphodiesterase-4 inhibition as a therapeutic strategy for metabolic disorders.PDE4B as a microglia target to reduce neuroinflammation.Modulation of the cAMP response by Gαi and Gβγ: a computational study of G protein signaling in immune cells.Effect of sphingosine kinase modulators on interleukin-1β release, sphingosine 1-phosphate receptor 1 expression and experimental autoimmune encephalomyelitis.Characterization of p87PIKAP, a novel regulatory subunit of phosphoinositide 3-kinase gamma that is highly expressed in heart and interacts with PDE3B.RNA silencing identifies PDE4D5 as the functionally relevant cAMP phosphodiesterase interacting with beta arrestin to control the protein kinase A/AKAP79-mediated switching of the beta2-adrenergic receptor to activation of ERK in HEK293B2 cells.A Rationale for Targeting Extracellular Regulated Kinases ERK1 and ERK2 in Glioblastoma.Association between the PDE4D gene and ischaemic stroke in the Chinese Han population.Phosphorylation of cAMP-specific PDE4A5 (phosphodiesterase-4A5) by MK2 (MAPKAPK2) attenuates its activation through protein kinase A phosphorylation.
P2860
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P2860
Remodelling of the PDE4 cAMP phosphodiesterase isoform profile upon monocyte-macrophage differentiation of human U937 cells.
description
2004 nî lūn-bûn
@nan
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Remodelling of the PDE4 cAMP p ...... entiation of human U937 cells.
@ast
Remodelling of the PDE4 cAMP p ...... entiation of human U937 cells.
@en
type
label
Remodelling of the PDE4 cAMP p ...... entiation of human U937 cells.
@ast
Remodelling of the PDE4 cAMP p ...... entiation of human U937 cells.
@en
prefLabel
Remodelling of the PDE4 cAMP p ...... entiation of human U937 cells.
@ast
Remodelling of the PDE4 cAMP p ...... entiation of human U937 cells.
@en
P2860
P356
P1476
Remodelling of the PDE4 cAMP p ...... rentiation of human U937 cells
@en
P2093
David I Stirling
Malcolm C Shepherd
P2860
P304
P356
10.1038/SJ.BJP.0705770
P407
P577
2004-04-05T00:00:00Z