3,4-methylenedioxy-β-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome. - Test2 - elhamkhani - TriplyDB

3,4-methylenedioxy-β-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome.

3,4-methylenedioxy-β-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome.

http://www.wikidata.org/entity/Q35050189

about

Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation Molecular mechanisms regulating NLRP3 inflammasome activation To Extinguish the Fire from Outside the Cell or to Shutdown the Gas Valve Inside? Novel Trends in Anti-Inflammatory Therapies Inflammasomes: mechanism of action, role in disease, and therapeutics Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models The Synthetic β-Nitrostyrene Derivative CYT-Rx20 Inhibits Esophageal Tumor Growth and Metastasis via PI3K/AKT and STAT3 Pathways 3'-hydroxy-4'-methoxy-β-methyl-β-nitrostyrene inhibits tumorigenesis in colorectal cancer cells through ROS-mediated DNA damage and mitochondrial dysfunction.The tick salivary protein sialostatin L2 inhibits caspase-1-mediated inflammation during Anaplasma phagocytophilum infection.Serum amyloid A induces NLRP-3-mediated IL-1β secretion in neutrophils A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.Nitrostyrene Derivatives Act as RXRα Ligands to Inhibit TNFα Activation of NF-κB.Identification of compounds that modulate retinol signaling using a cell-based qHTS assay.Toll-like receptor 4-interacting SPA4 peptide suppresses the NLRP3 inflammasome in response to LPS and ATP stimuli Genipin inhibits NLRP3 and NLRC4 inflammasome activation via autophagy suppression.β-Nitrostyrenes as Potential Anti-leishmanial Agents.Targeting ASC in NLRP3 inflammasome by caffeic acid phenethyl ester: a novel strategy to treat acute gout.Post-translational regulation of inflammasomes.CYT-Rx20 inhibits ovarian cancer cells in vitro and in vivo through oxidative stress-induced DNA damage and cell apoptosis.Oxalate, inflammasome, and progression of kidney disease Viral Infection Sensitizes Human Fetal Membranes to Bacterial Lipopolysaccharide by MERTK Inhibition and Inflammasome Activation.BOT-4-one attenuates NLRP3 inflammasome activation: NLRP3 alkylation leading to the regulation of its ATPase activity and ubiquitination.FcγR mediates TLR2- and Syk-dependent NLRP3 inflammasome activation by inactivated Francisella tularensis LVS immune complexes.Boron-Based Inhibitors of the NLRP3 Inflammasome.Baicalin Inhibits NOD-Like Receptor Family, Pyrin Containing Domain 3 Inflammasome Activation in Murine Macrophages by Augmenting Protein Kinase A Signaling.Inflammasomes, the eye and anti-inflammasome therapy.NS1 protein of 2009 pandemic influenza A virus inhibits porcine NLRP3 inflammasome-mediated interleukin-1 beta production by suppressing ASC ubiquitination.Inflammasomes in neurological diseases: emerging pathogenic and therapeutic concepts.OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders.A new lead to NLRP3 inhibition.Visualization and quantification of dynamic STAT3 homodimerization in living cells using homoFluoppi.Scutellarin Suppresses NLRP3 Inflammasome Activation in Macrophages and Protects Mice against Bacterial Sepsis.Anti-Inflammatory Potential of 1-Nitro-2-Phenylethylene.Synthesis and Biological Evaluation of Novel Benzimidazole Derivatives and Analogs Targeting the NLRP3 Inflammasome.Tranilast directly targets NLRP3 to treat inflammasome-driven diseases.Editorial: Flexible Syk: turning on and off the inflammasome as needed.Posttranslational Regulation of the NLR Family Pyrin Domain-Containing 3 Inflammasome.Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity.Comparisons of Halogenated β-Nitrostyrenes as Antimicrobial Agents

P2860

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P2860

3,4-methylenedioxy-β-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome.

http://www.wikidata.org/entity/Q35050189

description

2013 nî lūn-bûn

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2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

3,4-methylenedioxy-β-nitrostyr ...... assembly of the inflammasome.

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3,4-methylenedioxy-β-nitrostyr ...... assembly of the inflammasome.

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3,4-methylenedioxy-β-nitrostyr ...... assembly of the inflammasome.

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3,4-methylenedioxy-β-nitrostyr ...... assembly of the inflammasome.

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3,4-methylenedioxy-β-nitrostyr ...... assembly of the inflammasome.

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JBC.M113.515080

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Journal of Biological Chemistry

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3,4-methylenedioxy-β-nitrostyr ...... assembly of the inflammasome.

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Aaron Burberry

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Gabriel Núñez

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Raúl Muñoz-Planillo

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Saranyaraajan Varadarajan

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Yuan He

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P2860

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

Novel role of PKR in inflammasome activation and HMGB1 release

Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes

The inflammasomes

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

The Nalp3 inflammasome is essential for the development of silicosis

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