Interplay between ribosomal protein S27a and MDM2 protein in p53 activation in response to ribosomal stress. - Test2 - elhamkhani - TriplyDB

Interplay between ribosomal protein S27a and MDM2 protein in p53 activation in response to ribosomal stress.

Interplay between ribosomal protein S27a and MDM2 protein in p53 activation in response to ribosomal stress.

http://www.wikidata.org/entity/Q35067659

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Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1 Mutational analysis reveals a dual role of Mdm2 acidic domain in the regulation of p53 stability The importance of ribosome production, and the 5S RNP-MDM2 pathway, in health and disease Deubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1 Identification and expression of MMSA-8, and its clinical significance in multiple myeloma.Identification of Differentially Expressed Micrornas Associate with Glucose Metabolism in Different Organs of Blunt Snout Bream (Megalobrama amblycephala)Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis Ribosomal proteins and human diseases: pathogenesis, molecular mechanisms, and therapeutic implications Ribosomal proteins: functions beyond the ribosome Ribosomal proteins RPL37, RPS15 and RPS20 regulate the Mdm2-p53-MdmX network Growth inhibitory effects of large subunit ribosomal proteins in melanoma.Physical and functional interaction between ribosomal protein L11 and the tumor suppressor ARF.Therapeutic interventions to disrupt the protein synthetic machinery in melanoma Label-free quantitative protein profiling of vastus lateralis muscle during human aging.Monoubiquitination is critical for ovarian tumor domain-containing ubiquitin aldehyde binding protein 1 (Otub1) to suppress UbcH5 enzyme and stabilize p53 protein.Scission of the p53-MDM2 Loop by Ribosomal Proteins.Targeting the ubiquitin-mediated proteasome degradation of p53 for cancer therapy.MDM2's social network.Ribosomal proteins as novel players in tumorigenesis.Battle against cancer: an everlasting saga of p53.Otub1 stabilizes MDMX and promotes its proapoptotic function at the mitochondria Ribosomal proteins L11 and L5 activate TAp73 by overcoming MDM2 inhibition.Combinatorial action of transcription factors orchestrates cell cycle-dependent expression of the ribosomal protein genes and ribosome biogenesis.Ribosomal proteins L5 and L11 co-operatively inactivate c-Myc via RNA-induced silencing complex.Identification of ribosomal protein S25 (RPS25)-MDM2-p53 regulatory feedback loop.Ribosomal protein S14 unties the MDM2-p53 loop upon ribosomal stress.RP-MDM2-p53 Pathway: Linking Ribosomal Biogenesis and Tumor Surveillance.Epidermolysis bullosa - a group of skin diseases with different causes but commonalities in gene expression.The uS8, uS4, eS31, and uL14 Ribosomal Protein Genes Are Dysregulated in Nasopharyngeal Carcinoma Cell Lines Ribosomal protein L4 is a novel regulator of the MDM2-p53 loop.Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts.Desferrioxamine attenuates doxorubicin-induced acute cardiotoxicity through TFG-β/Smad p53 pathway in rat model.Balanced production of ribosome components is required for proper G1/S transition in Saccharomyces cerevisiae.The ribosomal protein S26 regulates p53 activity in response to DNA damage.How Ribosomes Translate Cancer.BCCIPβ modulates the ribosomal and extraribosomal function of S7 through a direct interaction.

P2860

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P2860

Interplay between ribosomal protein S27a and MDM2 protein in p53 activation in response to ribosomal stress.

http://www.wikidata.org/entity/Q35067659

description

2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Interplay between ribosomal pr ...... response to ribosomal stress.

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Interplay between ribosomal pr ...... response to ribosomal stress.

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JBC.M111.223651

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Journal of Biological Chemistry

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Interplay between ribosomal pr ...... response to ribosomal stress.

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P2093

Kishore B Challagundla

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Mu-Shui Dai

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Tiffany DeVine

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Xiao-Xin Sun

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P2860

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: binding to MDM2, stabilization of p53 protein, and activation of p53 function

Ribosomal proteins are targets for the NEDD8 pathway

Inhibition of c-Myc activity by ribosomal protein L11

Ribosomal protein S27-like and S27 interplay with p53-MDM2 axis as a target, a substrate and a regulator

Mdm2 promotes the rapid degradation of p53

Inhibition of HDM2 and activation of p53 by ribosomal protein L23

Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibition

Essential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activation

The first 30 years of p53: growing ever more complex

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22730-22741

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10.1074/JBC.M111.223651

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26

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286

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