The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor. - Test2 - elhamkhani - TriplyDB

The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor.

The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor.

http://www.wikidata.org/entity/Q35105986

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Redox regulation of FoxO transcription factors Regulation of protein quality control by UBE4B and LSD1 through p53-mediated transcription A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol p38α MAPK-mediated induction and interaction of FOXO3a and p53 contribute to the inhibited-growth and induced-apoptosis of human lung adenocarcinoma cells by berberine.Extracellular signal-regulated kinase signaling-mediated induction and interaction of FOXO3a and p53 contribute to the inhibition of nasopharyngeal carcinoma cell growth by curcumin Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition.Threonine 32 (Thr32) of FoxO3 is critical for TGF-β-induced apoptosis via Bim in hepatocarcinoma cells.Extra-Nuclear Signaling Pathway Involved in Progesterone-Induced Up-Regulations of p21cip1 and p27kip1 in Male Rat Aortic Smooth Muscle Cells.Autophagy induction by leptin contributes to suppression of apoptosis in cancer cells and xenograft model: involvement of p53/FoxO3A axis Cytosolic Extract of Human Adipose Stem Cells Reverses the Amyloid Beta-Induced Mitochondrial Apoptosis via P53/Foxo3a Pathway.High-Resolution Genomic Profiling of Disseminated Tumor Cells in Prostate Cancer FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damage.Qing'E formula alleviates the aging process in D-galactose-induced aging mice.Genomic profiling defines subtypes of prostate cancer with the potential for therapeutic stratification Cell differentiation versus cell death: extracellular glucose is a key determinant of cell fate following oxidative stress exposure.FOXO transcription factors in cancer development and therapy.The effects of proliferation and DNA damage on hematopoietic stem cell function determine aging.Tumor suppressor FOXO3 regulates ribonucleotide reductase subunit RRM2B and impacts on survival of cancer patients.Genome-wide analysis of p53-regulated transcription in Myc-driven lymphomas.Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling.5-methoxytryptophan protects MSCs from stress induced premature senescence by upregulating FoxO3a and mTOR.FOXO Signaling Pathways as Therapeutic Targets in Cancer.Restraining FOXO3-dependent transcriptional BMF activation underpins tumour growth and metastasis of E-cadherin-negative breast cancer FOXO3 longevity interactome on chromosome 6 p53: key conductor of all anti-acne therapies.Bcl2 deficiency activates FoxO through Akt inactivation and accelerates osteoblast differentiation Characterization of the direct targets of FOXO transcription factors throughout evolution.FoxO proteins or loss of functional p53 maintain stemness of glioblastoma stem cells and survival after ionizing radiation plus PI3K/mTOR inhibition.A comprehensive and high-resolution genome-wide response of p53 to stress.Transient mitochondrial DNA double strand breaks in mice cause accelerated aging phenotypes in a ROS-dependent but p53/p21-independent manner.Augmentation of oxidative stress-induced apoptosis in MCF7 cells by ascorbate-tamoxifen and/or ascorbate-juglone treatments.Suppression of Activated FOXO Transcription Factors in the Heart Prolongs Survival in a Mouse Model of Laminopathies.Gain-of-function mutant p53 promotes the oncogenic potential of head and neck squamous cell carcinoma cells by targeting the transcription factors FOXO3a and FOXM1.FoxO transcription factors in cancer metabolism.17β-Estradiol Protects Skeletal Myoblasts From Apoptosis Through p53, Bcl-2, and FoxO Families.[Aging and the control of the insulin-FOXO signaling pathway].JNK-dependent downregulation of FoxO1 is required to promote the survival of fibroblast-like synoviocytes in rheumatoid arthritis.Combretastatin A-4 induces p53 mitochondrial-relocalisation independent-apoptosis in non-small lung cancer cells.The longevity SNP rs2802292 uncovered: HSF1 activates stress-dependent expression of FOXO3 through an intronic enhancer.Azelaic acid reduced senescence-like phenotype in photo-irradiated human dermal fibroblasts: possible implication of PPARγ.

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P2860

The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor.

http://www.wikidata.org/entity/Q35105986

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor.

@ast

The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor.

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type

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The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor.

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The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor.

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The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor.

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The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor.

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The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor

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A Brunet

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C A Brady

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D Kenzelmann Broz

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P2860

PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

PUMA induces the rapid apoptosis of colorectal cancer cells

PUMA, a novel proapoptotic gene, is induced by p53

Negative control of p53 by Sir2alpha promotes cell survival under stress

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner

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3207-3221

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10.1038/ONC.2011.35

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29

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Otto Hannes Vogel

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50596738

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