Importazole, a small molecule inhibitor of the transport receptor importin-β
about
RanGTP and CLASP1 cooperate to position the mitotic spindle.Structural Basis of Targeting the Exportin CRM1 in CancerFine-tuning multiprotein complexes using small moleculesThe G protein α chaperone Ric-8 as a potential therapeutic targetRapid flow cytometric measurement of protein inclusions and nuclear trafficking.Human mutations affect the epigenetic/bookmarking function of HNF1BEssential elements for translation: the germline factor Vasa functions broadly in somatic cells.Personalization of the immunosuppressive treatment in renal transplant recipients: the great challenge in "omics" medicineNuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane.Chromosomal gain promotes formation of a steep RanGTP gradient that drives mitosis in aneuploid cells.Subcellular knockout of importin β1 perturbs axonal retrograde signaling.Live cell imaging of protein dislocation from the endoplasmic reticulum.Microtubule-dependent regulation of mitotic protein degradation.Ran-dependent TPX2 activation promotes acentrosomal microtubule nucleation in neurons.Targeting nucleocytoplasmic transport in cancer therapyColocalization of different influenza viral RNA segments in the cytoplasm before viral budding as shown by single-molecule sensitivity FISH analysis.Karyopherins: potential biological elements involved in the delayed graft function in renal transplant recipients.SINC, a type III secreted protein of Chlamydia psittaci, targets the inner nuclear membrane of infected cells and uninfected neighborsPositional Scanning Synthesis of a Peptoid Library Yields New Inducers of Apoptosis that Target Karyopherins and Tubulin.Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virusThe Hepatitis C Virus-Induced Membranous Web and Associated Nuclear Transport Machinery Limit Access of Pattern Recognition Receptors to Viral Replication SitesNuclear transport factors: global regulation of mitosis.Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential.Ciliary Entry of the Hedgehog Transcriptional Activator Gli2 Is Mediated by the Nuclear Import Machinery but Differs from Nuclear Transport in Being Imp-α/β1-IndependentKPNB1 mediates PER/CRY nuclear translocation and circadian clock function.Viral RNA Degradation and Diffusion Act as a Bottleneck for the Influenza A Virus Infection Efficiency.Karyopherin Alpha Proteins Regulate Oligodendrocyte Differentiation.Nuclear import of the thyroid hormone receptor α1 is mediated by importin 7, importin β1, and adaptor importin α1Androgen receptor splice variants circumvent AR blockade by microtubule-targeting agentsNucleosome functions in spindle assembly and nuclear envelope formation.RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence.Nuclear glutaredoxin 3 is critical for protection against oxidative stress-induced cell deathNuclear translocation of annexin 1 following oxygen-glucose deprivation-reperfusion induces apoptosis by regulating Bid expression via p53 binding.Increases in Retrograde Injury Signaling Complex-Related Transcripts in Central Axons following Injury.Towards Engineering Novel PE-Based Immunotoxins by Targeting Them to the NucleusHDAC10 promotes lung cancer proliferation via AKT phosphorylation.Transportin acts to regulate mitotic assembly events by target binding rather than Ran sequestration.TRIP13-deficient tubular epithelial cells are susceptible to apoptosis following acute kidney injury.Stimulated nuclear import by β-like importins.Importin β-dependent nuclear import of TopBP1 in ATR-Chk1 checkpoint in Xenopus egg extracts.
P2860
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P2860
Importazole, a small molecule inhibitor of the transport receptor importin-β
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Importazole, a small molecule inhibitor of the transport receptor importin-β
@ast
Importazole, a small molecule inhibitor of the transport receptor importin-β
@en
type
label
Importazole, a small molecule inhibitor of the transport receptor importin-β
@ast
Importazole, a small molecule inhibitor of the transport receptor importin-β
@en
prefLabel
Importazole, a small molecule inhibitor of the transport receptor importin-β
@ast
Importazole, a small molecule inhibitor of the transport receptor importin-β
@en
P2093
P2860
P356
P1433
P1476
Importazole, a small molecule inhibitor of the transport receptor importin-β
@en
P2093
Jonathan F Soderholm
Keisuke Hasegawa
Michael Uehara-Bingen
Petr Kalab
Stephen L Bird
Yasaswini Sampathkumar
P2860
P304
P356
10.1021/CB2000296
P577
2011-04-21T00:00:00Z