NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region. - Test2 - elhamkhani - TriplyDB

NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region.

NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region.

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Structural probes in quadruplex nucleic acid structure determination by NMR G-quadruplex formation in double strand DNA probed by NMM and CV fluorescence.Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence The SARS-Unique Domain (SUD) of SARS Coronavirus Contains Two Macrodomains That Bind G-Quadruplexes A G-Rich Sequence within the c-kit Oncogene Promoter Forms a Parallel G-Quadruplex Having Asymmetric G-Tetrad Dynamics Structure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K+ solution: insights into the interconversion of human telomeric G-quadruplex structures Solution structure of all parallel G-quadruplex formed by the oncogene RET promoter sequence c-MYC promoter G-quadruplex formed at the 5'-end of NHE III1 element: insights into biological relevance and parallel-stranded G-quadruplex stability Solution Structure of a 2:1 Quindoline–c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug Design Solution-state structure of an intramolecular G-quadruplex with propeller, diagonal and edgewise loops Metal Cations in G-Quadruplex Folding and Stability G-Quadruplex in the NRF2 mRNA 5' Untranslated Region Regulates De Novo NRF2 Protein Translation under Oxidative Stress Intramolecular DNA quadruplexes with different arrangements of short and long loops Diffusion-ordered nuclear magnetic resonance spectroscopy for analysis of DNA secondary structural elements.Biochemical techniques for the characterization of G-quadruplex structures: EMSA, DMS footprinting, and DNA polymerase stop assay.Verification of specific G-quadruplex structure by using a novel cyanine dye supramolecular assembly: II. The binding characterization with specific intramolecular G-quadruplex and the recognizing mechanism I-motif structures formed in the human c-MYC promoter are highly dynamic--insights into sequence redundancy and I-motif stability Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential.G-rich oligonucleotides inhibit HIF-1alpha and HIF-2alpha and block tumor growth.Molecular cloning of the human platelet-derived growth factor receptor beta (PDGFR-beta) promoter and drug targeting of the G-quadruplex-forming region to repress PDGFR-beta expression Structural insights into G-quadruplexes: towards new anticancer drugs.Emulsified BMVC derivative induced filtration for G-quadruplex DNA structural separation The proximal promoter region of the human vascular endothelial growth factor gene has a G-quadruplex structure that can be targeted by G-quadruplex-interactive agents.The major G-quadruplex formed in the human BCL-2 proximal promoter adopts a parallel structure with a 13-nt loop in K+ solution "One ring to bind them all"-part I: the efficiency of the macrocyclic scaffold for g-quadruplex DNA recognition.The cellular protein nucleolin preferentially binds long-looped G-quadruplex nucleic acids.Resolution and characterization of the structural polymorphism of a single quadruplex-forming sequence.Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?The C-terminus of nucleolin promotes the formation of the c-MYC G-quadruplex and inhibits c-MYC promoter activity.Possible regulatory roles of promoter g-quadruplexes in cardiac function-related genes - human TnIc as a model.Conformational changes in quadruplex oligonucleotide structures probed by Raman spectroscopy The role of G-quadruplex/i-motif secondary structures as cis-acting regulatory elements.Structure-based drug design: from nucleic acid to membrane protein targets.Quadruplex formation is necessary for stable PNA invasion into duplex DNA of BCL2 promoter region An improved model for the hTERT promoter quadruplex Molecular docking and dynamics simulations on the interaction of cationic porphyrin-anthraquinone hybrids with DNA G-quadruplexes.A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer Separation of Quadruplex Polymorphism in DNA Sequences by Reversed-Phase Chromatography.A G-quadruplex-binding macrodomain within the "SARS-unique domain" is essential for the activity of the SARS-coronavirus replication-transcription complex.

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P2860

NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region.

http://www.wikidata.org/entity/Q35130452

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2006 nî lūn-bûn

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2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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NMR solution structure of the ...... he human BCL2 promoter region.

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NMR solution structure of the ...... he human BCL2 promoter region.

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NMR solution structure of the ...... he human BCL2 promoter region.

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Danzhou Yang

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Ding Chen

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Jixun Dai

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Laurence H Hurley

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Roger A Jones

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CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

The human insulin gene linked polymorphic region exhibits an altered DNA structure

Formation and properties of hairpin and tetraplex structures of guanine-rich regulatory sequences of muscle-specific genes

Structure, internal motions and association-dissociation kinetics of the i-motif dimer of d(5mCCTCACTCC).

Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents.

Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex

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