Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators.
about
DNA damage, homology-directed repair, and DNA methylationBRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations.In vivo functional analysis of the histone 3-like TAF9 and a TAF9-related factor, TAF9LTranscriptional repression by the insulator protein CTCF involves histone deacetylasesThe insulation of genes from external enhancers and silencing chromatin.Structural dynamics of nucleosomes at single-molecule resolutionEpigenetic regulation of fetal globin gene expression in adult erythroid cellsPosttranslational modifications, localization, and protein interactions of optineurin, the product of a glaucoma geneAn activation-independent role of transcription factors in insulator function.Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteinsMICoA, a novel metastasis-associated protein 1 (MTA1) interacting protein coactivator, regulates estrogen receptor-alpha transactivation functionsMethylation-mediated silencing of TMS1/ASC is accompanied by histone hypoacetylation and CpG island-localized changes in chromatin architectureInsulators: exploiting transcriptional and epigenetic mechanismsEpigenetic boundaries of tumour suppressor gene promoters: the CTCF connection and its role in carcinogenesisTransitions in histone acetylation reveal boundaries of three separately regulated neighboring lociIdentification of Arabidopsis histone deacetylase HDA6 mutants that affect transgene expressionShielding of sleeping beauty DNA transposon-delivered transgene cassettes by heterologous insulators in early embryonal cellsIntraclonal protein expression heterogeneity in recombinant CHO cellsMutagenesis in rodents using the L1 retrotransposonA novel CpG-free vertebrate insulator silences the testis-specific SP-10 gene in somatic tissues: role for TDP-43 in insulator function.Cell cycle-regulated histone acetylation required for expression of the yeast HO gene.Proliferation control strategies to improve productivity and survival during CHO based production culture : A summary of recent methods employed and the effects of proliferation control in product secreting CHO cell linesCytomegalovirus replicon-based regulation of gene expression in vitro and in vivo.Generation of dwarf goat (Capra hircus) clones following nuclear transfer with transfected and nontransfected fetal fibroblasts and in vitro-matured oocytes.Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrantsGene specificity of suppression of transgene-mediated insertional transcriptional activation by the chicken HS4 insulator.In vivo expression of MHC class I genes depends on the presence of a downstream barrier elementThe 3' region of the chicken hypersensitive site-4 insulator has properties similar to its core and is required for full insulator activity.VEZF1 elements mediate protection from DNA methylation.DNA demethylation.Complete biallelic insulation at the H19/Igf2 imprinting control region position results in fetal growth retardation and perinatal lethalityDNA methyltransferase 1-associated protein (DMAP1) is a co-repressor that stimulates DNA methylation globally and locally at sites of double strand break repairUsing nanoBRET and CRISPR/Cas9 to monitor proximity to a genome-edited protein in real-time.Stable expression and cell-specific chromatin structure of human alpha1-antitrypsin cosmid transgenes in rat hepatoma cells.P15INK4b gene methylation and myelodysplastic syndromes.Dividing the empire: boundary chromatin elements delimit the territory of enhancers.BAC TG-EMBED: one-step method for high-level, copy-number-dependent, position-independent transgene expression.Matrix attachment region-dependent function of the immunoglobulin mu enhancer involves histone acetylation at a distance without changes in enhancer occupancy.Histone crosstalk directed by H2B ubiquitination is required for chromatin boundary integrityAcetylation of a specific promoter nucleosome accompanies activation of the epsilon-globin gene by beta-globin locus control region HS2.
P2860
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P2860
Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators.
description
1998 nî lūn-bûn
@nan
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Loss of transcriptional activi ...... nd is prevented by insulators.
@ast
Loss of transcriptional activi ...... nd is prevented by insulators.
@en
type
label
Loss of transcriptional activi ...... nd is prevented by insulators.
@ast
Loss of transcriptional activi ...... nd is prevented by insulators.
@en
prefLabel
Loss of transcriptional activi ...... nd is prevented by insulators.
@ast
Loss of transcriptional activi ...... nd is prevented by insulators.
@en
P2093
P2860
P356
P1433
P1476
Loss of transcriptional activi ...... nd is prevented by insulators.
@en
P2093
F Recillas-Targa
G Felsenfeld
M J Pikaart
P2860
P304
P356
10.1101/GAD.12.18.2852
P577
1998-09-01T00:00:00Z