Unravelling the genomic targets of small molecules using high-throughput sequencing.
about
Genome-wide epigenomic profiling for biomarker discoveryChromatin Regulates Genome Targeting with Cisplatin.ChIP-Seq: Library Preparation and Sequencing.Genome-wide Mapping of Drug-DNA Interactions in Cells with COSMIC (Crosslinking of Small Molecules to Isolate Chromatin)Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discoveryNew insights into functional regulation in MS-based drug profiling.Direct visualization of both DNA and RNA quadruplexes in human cells via an uncommon spectroscopic methodSynthetic genome readers target clustered binding sites across diverse chromatin states.A Scalable Epitope Tagging Approach for High Throughput ChIP-Seq Analysis.The cancer epigenome: Concepts, challenges, and therapeutic opportunities.G-quadruplex structures mark human regulatory chromatin.Personalized Therapy of Hypertension: the Past and the Future.Improving understanding of chromatin regulatory proteins and potential implications for drug discovery.The nucleosome: orchestrating DNA damage signaling and repair within chromatin.The molecular hallmarks of epigenetic control.RNA G-quadruplexes and their potential regulatory roles in translation.Genome-Wide Assessment of the Binding Effects of Artificial Transcriptional Activators by High-Throughput Sequencing.High-throughput sequencing of DNA G-quadruplex structures in the human genome.Click chemistry enables preclinical evaluation of targeted epigenetic therapies.Double duty: ZMYND8 in the DNA damage response and cancer.TWJ-Screen: an isothermal screening assay to assess ligand/DNA junction interactions in vitro.Red/NIR G-Quadruplex Sensing, Harvesting Blue Light by a Coumarin-Naphthalene Diimide Dyad.Iron-dependent lysosomal dysfunction mediated by a natural product hybrid.Surface-promoted aggregation of amphiphilic quadruplex ligands drives their selectivity for alternative DNA structures.
P2860
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P2860
Unravelling the genomic targets of small molecules using high-throughput sequencing.
description
2014 nî lūn-bûn
@nan
2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Unravelling the genomic targets of small molecules using high-throughput sequencing.
@ast
Unravelling the genomic targets of small molecules using high-throughput sequencing.
@en
type
label
Unravelling the genomic targets of small molecules using high-throughput sequencing.
@ast
Unravelling the genomic targets of small molecules using high-throughput sequencing.
@en
prefLabel
Unravelling the genomic targets of small molecules using high-throughput sequencing.
@ast
Unravelling the genomic targets of small molecules using high-throughput sequencing.
@en
P2860
P356
P1476
Unravelling the genomic targets of small molecules using high-throughput sequencing.
@en
P2093
Kyle M Miller
P2860
P2888
P304
P356
10.1038/NRG3796
P577
2014-10-14T00:00:00Z