Constitutively active Akt induces enhanced myelination in the CNS - Test2 - elhamkhani - TriplyDB

Constitutively active Akt induces enhanced myelination in the CNS

Constitutively active Akt induces enhanced myelination in the CNS

http://www.wikidata.org/entity/Q35394901

about

Neuregulin and BDNF induce a switch to NMDA receptor-dependent myelination by oligodendrocytes Oligodendrocyte Injury and Pathogenesis of HIV-1-Associated Neurocognitive Disorders Regulating Axonal Responses to Injury: The Intersection between Signaling Pathways Involved in Axon Myelination and The Inhibition of Axon Regeneration Remyelination Therapy in Multiple Sclerosis Balancing Proliferation and Connectivity in PTEN-associated Autism Spectrum Disorder Kif14 mutation causes severe brain malformation and hypomyelination Kif13b Regulates PNS and CNS Myelination through the Dlg1 Scaffold Oligodendrocyte precursor cell-intrinsic effect of Rheb1 controls differentiation and mediates mTORC1-dependent myelination in brain Activation of the mammalian target of rapamycin (mTOR) is essential for oligodendrocyte differentiation Regulatory mechanisms that mediate tenascin C-dependent inhibition of oligodendrocyte precursor differentiation MicroRNA-23a promotes myelination in the central nervous system Estrogen receptor β ligand therapy activates PI3K/Akt/mTOR signaling in oligodendrocytes and promotes remyelination in a mouse model of multiple sclerosis.Estrogen receptor (ER) β expression in oligodendrocytes is required for attenuation of clinical disease by an ERβ ligand Rapid assessment of internodal myelin integrity in central nervous system tissue.Germline disruption of Pten localization causes enhanced sex-dependent social motivation and increased glial production.P0 (protein zero) mutation S34C underlies instability of internodal myelin in S63C mice.PTEN inhibitor bisperoxovanadium protects oligodendrocytes and myelin and prevents neuronal atrophy in adult rats following cervical hemicontusive spinal cord injury.Inhibition of Drp1 hyper-activation is protective in animal models of experimental multiple sclerosis.Pten loss in Olig2 expressing neural progenitor cells and oligodendrocytes leads to interneuron dysplasia and leukodystrophy.In situ fluorescence imaging of myelination SHP-2 promotes the maturation of oligodendrocyte precursor cells through Akt and ERK1/2 signaling in vitro.Cyclin-dependent kinase 5 mediates adult OPC maturation and myelin repair through modulation of Akt and GsK-3β signaling.Cdo interacts with APPL1 and activates Akt in myoblast differentiation.Zebrafish regenerate full thickness optic nerve myelin after demyelination, but this fails with increasing age.Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination White matter alterations in bipolar disorder: potential for drug discovery and development.Daam2-PIP5K is a regulatory pathway for Wnt signaling and therapeutic target for remyelination in the CNS Disturbed macro-connectivity in schizophrenia linked to oligodendrocyte dysfunction: from structural findings to molecules.A novel PET marker for in vivo quantification of myelination.Longitudinal near-infrared imaging of myelination.Multiple functional therapeutic effects of the estrogen receptor β agonist indazole-Cl in a mouse model of multiple sclerosis Neurotrophin-3 targets the translational initiation machinery in oligodendrocytes.Phosphorylation of LKB1/Par-4 establishes Schwann cell polarity to initiate and control myelin extent The myelin brake: when enough is enough.Molecular and phenotypic abnormalities in individuals with germline heterozygous PTEN mutations and autism Visual abnormalities associated with enhanced optic nerve myelination Interaction of mTOR and Erk1/2 signaling to regulate oligodendrocyte differentiation.SRY-box containing gene 17 regulates the Wnt/β-catenin signaling pathway in oligodendrocyte progenitor cells.Erk1/2 MAPK and mTOR signaling sequentially regulates progression through distinct stages of oligodendrocyte differentiation.Role of fibroblast growth factor receptors in astrocytic stem cells

P2860

Q21145719-AC97CF29-777D-4F9E-A6C7-C3F43358B886 Q26741723-1D08C164-4361-47C8-B9C2-62931BF9E735 Q26745419-F5A65D4B-90DB-4393-9933-FE5510F44EF4 Q26772359-ABD4C387-29B4-4002-8591-C53239BF5389 Q26822064-FEA19412-7421-4285-A212-90DB59D09CBE Q27321348-38542A15-CFC0-4BAB-B22F-03FE7B4FFFF5 Q27342977-CC11C829-0177-4F87-8274-A1FA1E22629B Q28508935-080E4923-94DD-4285-B086-A6B870B4089F Q28568907-6E906A38-12D6-4308-834F-DAC278B08F98 Q28572328-D3FD5146-090F-44A2-913D-2D6E3C64365E Q28589529-7EB98A9F-009A-489E-8E67-AD6D4FEAA422 Q30433883-C321ED90-8AF1-4DDD-9E87-85D737B29326 Q30446108-A3DECEA9-C8AB-4687-A0EB-4C0286BBC55E Q33618194-9CDF20E6-BE47-46A7-BB7B-AA158C4C9918 Q33649301-E07192DE-BC89-4D41-B206-1B67E2BC7D52 Q33715265-CA3CC797-16EA-4835-8F06-88EF29A98814 Q33748155-6B34049A-2D67-425A-84D6-2594061244FE Q33833201-CF9E4DF9-2173-46C6-9E1C-3382B099AD6D Q33895438-10CAAB05-04B0-41B8-95B4-0FF26BAE1F15 Q33928806-9CB244D6-6A71-46EB-AEAD-0644F665DB7A Q33941989-53F392FD-CF61-45EA-A29C-E8D41A1E375E Q33969865-C147A090-7233-439D-A174-ABE2BB4E708C Q33992551-594A03FC-619C-404C-83CD-1992589F1870 Q34184853-52FB91B9-BFAE-4254-8BAC-B5185A52C2B0 Q34253257-845E9840-A786-4B72-A55B-1DA61F299400 Q34406905-B3D459AF-53ED-444B-BB37-691F23D3A2F3 Q34466406-B4E094AD-C3DE-4D4B-82FD-F32256954F07 Q34531769-FBC08EBF-52C9-4F92-AA7F-068BDCEA7FC0 Q34603248-92FC88EB-255C-489A-A72F-2C36E6D9DFDA Q34603512-B87AB2FF-F072-4111-8A59-EE91BA973238 Q34752088-2EA7AFBC-005B-48D2-930D-E50A9C06D023 Q34992053-10EFFAC3-F056-4584-A613-EA243A338CE5 Q35101108-02F3F24B-628C-4C78-B494-8292C6264147 Q35219969-E6285546-F80B-4129-88F0-2CA0630073D3 Q35304904-CB9811CC-8D1F-42DD-A95A-0B3D4441D47B Q35394678-25ED51F8-F96F-4777-B225-4A8EF1F5201A Q35523618-DD575FB0-D6D8-4151-80D8-E1AA5AD84D27 Q35582551-16E38BEC-30B8-49D1-A47A-1F7E55FBCA53 Q35693398-7160B00F-3D3F-4CA1-BA5D-E75550A7F83B Q35757855-E7C67700-F6A6-43E9-9715-584A7D553B92

P2860

Constitutively active Akt induces enhanced myelination in the CNS

http://www.wikidata.org/entity/Q35394901

description

2008 nî lūn-bûn

@nan

2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Constitutively active Akt induces enhanced myelination in the CNS

@ast

Constitutively active Akt induces enhanced myelination in the CNS

@en

type

label

Constitutively active Akt induces enhanced myelination in the CNS

@ast

Constitutively active Akt induces enhanced myelination in the CNS

@en

prefLabel

Constitutively active Akt induces enhanced myelination in the CNS

@ast

Constitutively active Akt induces enhanced myelination in the CNS

@en

P1433

Q35394901-12BBBE16-12F9-442E-B9C7-5D4EEC680744

P1476

Q35394901-76D9E19E-FDD2-4855-9FC3-95CF2CEDC50E

P2093

Q35394901-2F8D74C0-1762-43E7-976F-4B3BFA2A034C

Q35394901-3E05B1F9-5BE8-43AF-B422-AB9A84E1C789

Q35394901-72531F69-D650-4B0B-A793-8D49E8661FD7

Q35394901-9311F920-0216-4501-AAD4-27B0E75F40F5

Q35394901-AD266154-3FC0-46AD-A583-2EF6DA67177B

Q35394901-C69BF220-091E-42EE-AA89-87942472BA95

Q35394901-F0FC8308-DA1E-4DC3-B894-F3EE2B779D0E

P2860

Q35394901-01B444CA-26CB-41FE-A5F1-1E9950155B5D

Q35394901-02DEDDC1-278E-4FE9-B112-7E5127354951

Q35394901-099B41D7-9C43-4952-B3A3-D06A2BFDA7F7

Q35394901-1046A8FE-DEF1-40F9-B374-D1E6E1F0B3A3

Q35394901-13C0EA14-F8B9-4056-A6B6-154179E60D4C

Q35394901-14396FAA-F824-418C-B788-92101DF251DB

Q35394901-1C7E017D-F159-4218-8610-C807C1FD6020

Q35394901-1FBC0ED1-6E4C-469A-A42C-DAEFD8E961F5

Q35394901-28327E8D-72B6-49C4-BB1E-822AC44150C2

Q35394901-2EF19F57-1BCA-4EF8-A502-379040994FE4

P304

Q35394901-C3EC57E2-B493-4D2C-8C0B-570771F8CF1E

P31

Q35394901-AB47A96D-E989-4DC2-9C21-844AEE4AD004

P356

Q35394901-7856DD26-D6AF-4E52-95CD-A99F2E972BB8

P407

Q35394901-728FE077-8A8C-49D2-8153-9EA0E7CB1E48

P433

Q35394901-538F1752-3552-4756-A9C2-510BF52E46CD

P478

Q35394901-092454C0-B8C6-477D-A292-7AF6176FD2F8

P50

Q35394901-802E646C-F9CB-463E-BFF0-EBAFAA897EA6

Q35394901-D7FC147E-749A-478A-BDCC-A9DB0F63BFCC

P577

Q35394901-8320306E-9DB5-4A67-B1E4-728D4BBEECE8

P5875

Q35394901-1DC7EDD2-1198-4F1B-A782-ABF9A1F4F2FE

P698

Q35394901-43442407-586F-43DD-AC83-DCEF8F1BDB12

P932

Q35394901-4BD9581C-9226-4FF1-82C8-09C4965CA931

P356

JNEUROSCI.0150-08.2008

P1433

Journal of Neuroscience

P1476

Constitutively active Akt induces enhanced myelination in the CNS

@en

P2093

Ana I Flores

http://www.w3.org/2001/XMLSchema#string

Emily N Morse

http://www.w3.org/2001/XMLSchema#string

Grahame Kidd

http://www.w3.org/2001/XMLSchema#string

H Elizabeth Shick

http://www.w3.org/2001/XMLSchema#string

Robin L Avila

http://www.w3.org/2001/XMLSchema#string

Wendy B Macklin

http://www.w3.org/2001/XMLSchema#string

Xinghua Yin

http://www.w3.org/2001/XMLSchema#string

P2860

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

Morphological evidence of alteration in myelinstructure with maturation

Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia

Axonal neuregulin-1 regulates myelin sheath thickness

Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3beta and its upstream regulators

Neuregulin-1 type III determines the ensheathment fate of axons

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

IGF-1 protects oligodendrocyte progenitors against TNFalpha-induced damage by activation of PI3K/Akt and interruption of the mitochondrial apoptotic pathway.

Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression.

P304

7174-7183

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1523/JNEUROSCI.0150-08.2008

http://www.w3.org/2001/XMLSchema#string

P407

P433

28

http://www.w3.org/2001/XMLSchema#string

P478

28

http://www.w3.org/2001/XMLSchema#string

P50

Priya Narayanan

Daniel A Kirschner

P577

2008-07-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5237428

http://www.w3.org/2001/XMLSchema#string

P698

18614687

http://www.w3.org/2001/XMLSchema#string

P932

4395496

http://www.w3.org/2001/XMLSchema#string