Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization - Test2 - elhamkhani - TriplyDB

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

http://www.wikidata.org/entity/Q28290083

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GSK-3 Inhibitors: Preclinical and Clinical Focus on CNS The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention A Complex Interplay between Wnt/β-Catenin Signalling and the Cell Cycle in the Adult Liver GSK-3β: A Bifunctional Role in Cell Death Pathways Polo-like kinase 3 is required for entry into S phase PIKE-A is required for prolactin-mediated STAT5a activation in mammary gland development The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation.mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3beta Disruption of platelet-derived growth factor-dependent phosphatidylinositol 3-kinase and phospholipase Cγ 1 activity abolishes vascular smooth muscle cell proliferation and migration and attenuates neointima formation in vivo Microsomal prostaglandin E synthase-1 promotes hepatocarcinogenesis through activation of a novel EGR1/β-catenin signaling axis Interaction of Akt-phosphorylated SRPK2 with 14-3-3 mediates cell cycle and cell death in neurons Identification of a WD40 repeat-containing isoform of PHIP as a novel regulator of beta-cell growth and survival Isolation and characterization of cytoplasmic cyclin D1 mutants F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage Phosphorylation-dependent regulation of SCF(Fbx4) dimerization and activity involves a novel component, 14-3-3ɛ Cyclin D1 interacts and collaborates with Ral GTPases enhancing cell detachment and motility The PI3K-PDK1 connection: more than just a road to PKB Tumor suppressor SMAR1 mediates cyclin D1 repression by recruitment of the SIN3/histone deacetylase 1 complex Evidence of p53-dependent cross-talk between ribosome biogenesis and the cell cycle: effects of nucleolar protein Bop1 on G(1)/S transition Distinct subcellular localization patterns contribute to functional specificity of the Cln2 and Cln3 cyclins of Saccharomyces cerevisiae A novel role of IKKalpha in the mediation of UVB-induced G0/G1 cell cycle arrest response by suppressing Cyclin D1 expression Requirement of Cdk4 for v-Ha-ras-Induced Breast Tumorigenesis and Activation of the v-ras-Induced Senescence Program by the R24C Mutation GSK-3: tricks of the trade for a multi-tasking kinase Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy Rictor regulates FBXW7-dependent c-Myc and cyclin E degradation in colorectal cancer cells Growth control by intracellular tension and extracellular stiffness RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility.Molecular and cellular targets Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphoma Knockin of mutant PIK3CA activates multiple oncogenic pathways AKT/PKB signaling: navigating downstream Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex PTOV-1, a novel protein overexpressed in prostate cancer, shuttles between the cytoplasm and the nucleus and promotes entry into the S phase of the cell division cycle Transforming growth factor-beta and breast cancer: Cell cycle arrest by transforming growth factor-beta and its disruption in cancer The prolyl isomerase Pin1 in breast development and cancer Nuclear localization is required for Dishevelled function in Wnt/beta-catenin signaling A basis for a visual language for describing, archiving and analyzing functional models of complex biological systems PTEN deficiency: a role in mammary carcinogenesis.Deregulation of p27 by oncogenic signaling and its prognostic significance in breast cancer

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P2860

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

http://www.wikidata.org/entity/Q28290083

description

1998 nî lūn-bûn

@nan

1998 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

1998年の論文

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1998年論文

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1998年論文

@zh-hant

1998年論文

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1998年論文

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1998年論文

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1998年论文

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name

Glycogen synthase kinase-3beta ...... s and subcellular localization

@ast

Glycogen synthase kinase-3beta ...... s and subcellular localization

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Glycogen synthase kinase-3beta ...... s and subcellular localization

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type

label

Glycogen synthase kinase-3beta ...... s and subcellular localization

@ast

Glycogen synthase kinase-3beta ...... s and subcellular localization

@en

Glycogen synthase kinase-3beta ...... s and subcellular localization

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prefLabel

Glycogen synthase kinase-3beta ...... s and subcellular localization

@ast

Glycogen synthase kinase-3beta ...... s and subcellular localization

@en

Glycogen synthase kinase-3beta ...... s and subcellular localization

@nl

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Genes & Development

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Glycogen synthase kinase-3beta ...... s and subcellular localization

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C J Sherr

http://www.w3.org/2001/XMLSchema#string

J A Diehl

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M Cheng

http://www.w3.org/2001/XMLSchema#string

P2860

Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

New functional activities for the p21 family of CDK inhibitors

Association of the APC gene product with beta-catenin

Mdm2 promotes the rapid degradation of p53

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E

Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase

Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

CRM1 is an export receptor for leucine-rich nuclear export signals

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3499-3511

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scholarly article

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879769

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10.1101/GAD.12.22.3499

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22

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12

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Martine F Roussel

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1998-11-01T00:00:00Z

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13453300

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9832503

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317244

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