Flexible cullins in cullin-RING E3 ligases allosterically regulate ubiquitination.
about
The role of cullin 5-containing ubiquitin ligasesPrinciples of allosteric interactions in cell signalingMolecular Architecture of the Ankyrin SOCS Box Family of Cul5-Dependent E3 Ubiquitin LigasesMultimeric Complexes among Ankyrin-Repeat and SOCS-box Protein 9 (ASB9), ElonginBC, and Cullin 5: Insights into the Structure and Assembly of ECS-type Cullin-RING E3 Ubiquitin LigasesStructural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexesPaths of long-range communication in the E2 enzymes of family 3: a molecular dynamics investigation.Structural and functional insights to ubiquitin-like protein conjugation.Loop 7 of E2 enzymes: an ancestral conserved functional motif involved in the E2-mediated steps of the ubiquitination cascade.The structural basis for cancer treatment decisions.Induced protein degradation: an emerging drug discovery paradigm.Dynamic multiprotein assemblies shape the spatial structure of cell signalingMacromolecular juggling by ubiquitylation enzymes.Stability of HIB-Cul3 E3 ligase adaptor HIB Is Regulated by Self-degradation and Availability of Its Substrates.Probing the structural requirements of non-electrophilic naphthalene-based Nrf2 activators.Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia.Single-particle EM reveals extensive conformational variability of the Ltn1 E3 ligase.Dispersed sites of HIV Vif-dependent polyubiquitination in the DNA deaminase APOBEC3F.The role of allostery in the ubiquitin-proteasome systemThe spatial structure of cell signaling systems.Crystal Structure of the Cul2-Rbx1-EloBC-VHL Ubiquitin Ligase Complex.Design Principles Involving Protein Disorder Facilitate Specific Substrate Selection and Degradation by the Ubiquitin-Proteasome System.The E3 ubiquitin ligase CHIP and the molecular chaperone Hsc70 form a dynamic, tethered complex.The cullin-4 complex DCDC does not require E3 ubiquitin ligase elements to control heterochromatin in Neurospora crassa.Molecular dynamics simulations elucidate the mode of protein recognition by Skp1 and the F-box domain in the SCF complex.
P2860
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P2860
Flexible cullins in cullin-RING E3 ligases allosterically regulate ubiquitination.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Flexible cullins in cullin-RING E3 ligases allosterically regulate ubiquitination.
@ast
Flexible cullins in cullin-RING E3 ligases allosterically regulate ubiquitination.
@en
type
label
Flexible cullins in cullin-RING E3 ligases allosterically regulate ubiquitination.
@ast
Flexible cullins in cullin-RING E3 ligases allosterically regulate ubiquitination.
@en
prefLabel
Flexible cullins in cullin-RING E3 ligases allosterically regulate ubiquitination.
@ast
Flexible cullins in cullin-RING E3 ligases allosterically regulate ubiquitination.
@en
P2860
P356
P1476
Flexible cullins in cullin-RING E3 ligases allosterically regulate ubiquitination.
@en
P2860
P304
40934-40942
P356
10.1074/JBC.M111.277236
P407
P577
2011-09-20T00:00:00Z