Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages. - Test2 - elhamkhani - TriplyDB

Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages.

Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages.

http://www.wikidata.org/entity/Q35612957

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Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS Molecular Characterization of E-Type Prostanoid Receptor 4 (EP4) from Ayu (Plecoglossus altivelis) and Its Functional Analysis in the Monocytes/Macrophages.Myeloid Cell Prostaglandin E2 Receptor EP4 Modulates Cytokine Production but Not Atherogenesis in a Mouse Model of Type 1 Diabetes.Cytosolic phospholipase A2 contributes to innate immune defense against Candida albicans lung infection Major role of adipocyte prostaglandin E2 in lipolysis-induced macrophage recruitment Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue.Trial Watch-Small molecules targeting the immunological tumor microenvironment for cancer therapy.A novel "complement-metabolism-inflammasome axis" as a key regulator of immune cell effector function Human umbilical cord blood-stem cells direct macrophage polarization and block inflammasome activation to alleviate rheumatoid arthritis Interaction between integrin α5 and PDE4D regulates endothelial inflammatory signalling.Innate lymphoid cells: the role in respiratory infections and lung tissue damage.The role of caloric load and mitochondrial homeostasis in the regulation of the NLRP3 inflammasome.The NLRP3 and Pyrin Inflammasomes: Implications in the Pathophysiology of Autoinflammatory Diseases.Negative regulators and their mechanisms in NLRP3 inflammasome activation and signaling.The Induction of Pro-IL-1β by Lipopolysaccharide Requires Endogenous Prostaglandin E2 Production.T3SS effector ExoY reduces inflammasome-related responses by suppressing bacterial motility and delaying activation of NF-κB and caspase-1.Virus-induced inflammasome activation is suppressed by prostaglandin D2/DP1 signaling.Elevated prostaglandin E2 post-bone marrow transplant mediates interleukin-1β-related lung injury.Interaction of Mycoplasma hominis PG21 with Human Dendritic Cells: Interleukin-23-Inducing Mycoplasmal Lipoproteins and Inflammasome Activation of the Cell.Altered fatty acid metabolism and reduced stearoyl-coenzyme a desaturase activity in asthma.Loss of PHD3 in myeloid cells dampens the inflammatory response and fibrosis after hind-limb ischemia.17-oxo-DHA displays additive anti-inflammatory effects with fluticasone propionate and inhibits the NLRP3 inflammasome.Metabolic regulation of NLRP3.Prostaglandin E2 as a Regulator of Immunity to Pathogens.Inflammasomes in neurological diseases: emerging pathogenic and therapeutic concepts.Macrophage Cyclooxygenase-2 Protects Against Development of Diabetic Nephropathy.The resolution of acute inflammation induced by cyclic AMP is dependent on annexin A1.Restoration of the type I IFN-IL-1 balance through targeted blockade of PTGER4 inhibits autoimmunity in NOD mice.Indomethacin sensitizes resistant transformed cells to macrophage cytotoxicity.PGE2 /EP4 receptor attenuated mucosal injury via β-arrestin1/Src/EGFR-mediated proliferation in portal hypertensive gastropathy.Macrophages and the Recovery from Acute and Chronic Inflammation.Reining in uncontrolled inflammasome with PKA.Prostaglandin E2 receptor 3 (EP3) signaling is induced in placentas with unexplained recurrent pregnancy losses (uRPL).Posttranslational Regulation of the NLR Family Pyrin Domain-Containing 3 Inflammasome.

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Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages.

http://www.wikidata.org/entity/Q35612957

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Journal of Immunology

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Prostaglandin E2 Inhibits NLRP ...... clic AMP in Human Macrophages.

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Carolea Logun

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Daniel L Kastner

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Hai-Yan Qi

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James H Shelhamer

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Li-Yuan Chen

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Sara Alsaaty

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Yong Hwan Park

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Yueqin Liu

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P2860

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A

Regulation of immune responses by prostaglandin E2

Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic intervention

Gout-associated uric acid crystals activate the NALP3 inflammasome

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5472-5487

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A Martínez-Antón

Milena Sokolowska

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2015-04-27T00:00:00Z

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