Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways.
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The spectrum of SWI/SNF mutations, ubiquitous in human cancersTumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptorsThe CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive mannerRecent progress in pancreatic cancerIntegrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastomaKRAS, GNAS, and RNF43 mutations in intraductal papillary mucinous neoplasm of the pancreas: a meta-analysisControl of Wnt Receptor Turnover by R-spondin-ZNRF3/RNF43 Signaling Module and Its Dysregulation in CancerPancreatic cancer from bench to bedside: molecular pathways and treatment optionsCurrent concepts in the diagnosis and pathobiology of intraepithelial neoplasia: A review by organ systemCurrent perspectives on pancreatic serous cystic neoplasms: Diagnosis, management and beyondGenetics and biology of pancreatic ductal adenocarcinomaClinical approach to incidental pancreatic cystsDevelopmental Pathways Direct Pancreatic Cancer Initiation from Its Cellular OriginEarly detection of pancreatic cancerPrevalence, Diagnosis and Management of Pancreatic Cystic Neoplasms: Current Status and Future DirectionsCytology Specimen Management, Triage and Standardized Reporting of Fine Needle Aspiration Biopsies of the PancreasPancreatic adenocarcinoma pathology: changing "landscape"Evolution and dynamics of pancreatic cancer progressionMutational signatures: the patterns of somatic mutations hidden in cancer genomesEarly detection and prevention of pancreatic cancer: is it really possible today?Genetic basis of pancreas cancer development and progression: insights from whole-exome and whole-genome sequencingGenetically engineered mouse models of pancreatic adenocarcinomaHuman correlates of provocative questions in pancreatic pathologyStructural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondinA Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the PancreasA DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effectInactivating CUX1 mutations promote tumorigenesisSignatures of mutational processes in human cancerInsights into the Pathogenesis of Pancreatic Cystic Neoplasms.A combination of molecular markers and clinical features improve the classification of pancreatic cysts.Deep sequencing of cancer-related genes revealed GNAS mutations to be associated with intraductal papillary mucinous neoplasms and its main pancreatic duct dilation.Pathology and molecular genetics of pancreatic neoplasms.Ring finger protein 43 associates with gastric cancer progression and attenuates the stemness of gastric cancer stem-like cells via the Wnt-β/catenin signaling pathway.Diversity of Precursor Lesions For Pancreatic Cancer: The Genetics and Biology of Intraductal Papillary Mucinous NeoplasmWhole-exome sequencing of pancreatic neoplasms with acinar differentiationTargeted next-generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas.Pancreatic cancer genomics: insights and opportunities for clinical translationCalmodulin promotes matrix metalloproteinase 9 production and cell migration by inhibiting the ubiquitination and degradation of TBC1D3 oncoprotein in human breast cancer cells.The early detection of pancreatic cancer: what will it take to diagnose and treat curable pancreatic neoplasia?
P2860
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P2860
Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Whole-exome sequencing of neop ...... ubiquitin-dependent pathways.
@ast
Whole-exome sequencing of neop ...... ubiquitin-dependent pathways.
@en
type
label
Whole-exome sequencing of neop ...... ubiquitin-dependent pathways.
@ast
Whole-exome sequencing of neop ...... ubiquitin-dependent pathways.
@en
prefLabel
Whole-exome sequencing of neop ...... ubiquitin-dependent pathways.
@ast
Whole-exome sequencing of neop ...... ubiquitin-dependent pathways.
@en
P2093
P2860
P50
P356
P1476
Whole-exome sequencing of neop ...... ubiquitin-dependent pathways.
@en
P2093
Alison P Klein
Anirban Maitra
Barish H Edil
C Max Schmidt
Christopher L Wolfgang
David S Klimstra
G Johan A Offerhaus
Hannah Carter
James R Eshleman
P2860
P304
21188-21193
P356
10.1073/PNAS.1118046108
P407
P577
2011-12-08T00:00:00Z