Identification of a DYRK1A Inhibitor that Induces Degradation of the Target Kinase using Co-chaperone CDC37 fused with Luciferase nanoKAZ.
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DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down SyndromeSelective inhibition of the kinase DYRK1A by targeting its folding processRetinoid derivative Tp80 exhibits anti-hepatitis C virus activity through restoration of GI-GPx expression.DYRK1A inhibition as potential treatment for Alzheimer's disease.DYRK1B mutations associated with metabolic syndrome impair the chaperone-dependent maturation of the kinase domain.ATR Is a Therapeutic Target in Synovial Sarcoma.Mutational analysis of two residues in the DYRK homology box of the protein kinase DYRK1A.
P2860
Q26745413-F635643C-1916-4DF7-B6D0-5F77F6ACB057Q28834235-2FED9B9C-B470-411E-8ACE-E8BF1DB280BBQ36214085-DEAD9536-C2D6-4324-AD83-0E72FBDBCB74Q38807264-384EA62B-C660-4F2A-BE68-1637590A6119Q41124666-146AC6A3-3629-47A1-B983-0606DCC8CC95Q47643551-33396F5C-C010-49E2-BE73-46E68061B70EQ54979041-C71E7D4F-63CF-45A0-B37F-79A1092CD7C7
P2860
Identification of a DYRK1A Inhibitor that Induces Degradation of the Target Kinase using Co-chaperone CDC37 fused with Luciferase nanoKAZ.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Identification of a DYRK1A Inh ...... fused with Luciferase nanoKAZ.
@ast
Identification of a DYRK1A Inh ...... fused with Luciferase nanoKAZ.
@en
type
label
Identification of a DYRK1A Inh ...... fused with Luciferase nanoKAZ.
@ast
Identification of a DYRK1A Inh ...... fused with Luciferase nanoKAZ.
@en
prefLabel
Identification of a DYRK1A Inh ...... fused with Luciferase nanoKAZ.
@ast
Identification of a DYRK1A Inh ...... fused with Luciferase nanoKAZ.
@en
P2093
P2860
P50
P356
P1433
P1476
Identification of a DYRK1A Inh ...... fused with Luciferase nanoKAZ
@en
P2093
Masatoshi Hagiwara
Rie Sonamoto
Tomoe Kato-Sumida
Yuka Koike
Yukiko Okuno
P2860
P2888
P356
10.1038/SREP12728
P407
P577
2015-08-03T00:00:00Z