DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome

DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome

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http://www.wikidata.org/entity/Q26745413
Advances in transgenic animal models and techniques.Dyrk1 inhibition improves Alzheimer's disease-like pathology.Targeting trisomic treatments: optimizing Dyrk1a inhibition to improve Down syndrome deficits.Inhibition of DYRK1A disrupts neural lineage specification in human pluripotent stem cellsAn ELISA DYRK1A non-radioactive kinase assay suitable for the characterization of inhibitorsRodent models in Down syndrome research: impact and future opportunities.A wake-up call to quiescent cancer cells - potential use of DYRK1B inhibitors in cancer therapy.Overexpression of the DYRK1A Gene (Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A) Induces Alterations of the Serotoninergic and Dopaminergic Processing in Murine Brain Tissues.Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors: a survey of recent patent literature.Why West? Comparisons of clinical, genetic and molecular features of infants with and without spasms.Functional characterization of DYRK1A missense variants associated with a syndromic form of intellectual deficiency and autism.Molecular structures of cdc2-like kinases in complex with a new inhibitor chemotype.MuvB: A Key to Cell Cycle Control in Ovarian Cancer.DYRK1A Protein, A Promising Therapeutic Target to Improve Cognitive Deficits in Down SyndromeCorrection of cognitive deficits in mouse models of Down syndrome by a pharmacological inhibitor of DYRK1A
P2860

DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome

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http://www.wikidata.org/entity/Q26745413
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2016 nî lūn-bûn
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2016 թուականին հրատարակուած գիտական յօդուած
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2016 թվականին հրատարակված գիտական հոդված
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2016年の論文
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2016年論文
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2016年論文
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2016年論文
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2016年論文
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2016年論文
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2016年论文
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DYRK1A, a Dosage-Sensitive Gen ...... g Development in Down Syndrome
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DYRK1A, a Dosage-Sensitive Gen ...... g Development in Down Syndrome
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DYRK1A, a Dosage-Sensitive Gen ...... g Development in Down Syndrome
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DYRK1A, a Dosage-Sensitive Gen ...... g Development in Down Syndrome
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DYRK1A, a Dosage-Sensitive Gen ...... g Development in Down Syndrome
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DYRK1A, a Dosage-Sensitive Gen ...... g Development in Down Syndrome
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DYRK1A, a Dosage-Sensitive Gen ...... g Development in Down Syndrome
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DYRK1A, a Dosage-Sensitive Gen ...... g Development in Down Syndrome
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DYRK1A, a Dosage-Sensitive Gen ...... g Development in Down Syndrome
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DYRK1A, a Dosage-Sensitive Gen ...... g Development in Down Syndrome
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P2860
P304
P31
P3181
P356
P407
P478
P50
P577
P698
P921
P932