Randomized controlled trial of fosmidomycin-clindamycin versus sulfadoxine-pyrimethamine in the treatment of Plasmodium falciparum malaria - Test2 - elhamkhani - TriplyDB

Randomized controlled trial of fosmidomycin-clindamycin versus sulfadoxine-pyrimethamine in the treatment of Plasmodium falciparum malaria

Randomized controlled trial of fosmidomycin-clindamycin versus sulfadoxine-pyrimethamine in the treatment of Plasmodium falciparum malaria

http://www.wikidata.org/entity/Q35759028

about

Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum Inhibition of 1-Deoxy- d -Xylulose-5-Phosphate Reductoisomerase by Lipophilic Phosphonates: SAR, QSAR, and Crystallographic Studies Antimalarial and Structural Studies of Pyridine-Containing Inhibitors of 1-Deoxyxylulose-5-phosphate Reductoisomerase A chemical rescue screen identifies a Plasmodium falciparum apicoplast inhibitor targeting MEP isoprenoid precursor biosynthesis Malaria: an update on current chemotherapy.Comparative transcriptional analysis of homologous pathogenic and non-pathogenic Lawsonia intracellularis isolates in infected porcine cells The toxoplasma apicoplast phosphate translocator links cytosolic and apicoplast metabolism and is essential for parasite survival.Antimalarial compounds in Phase II clinical development.High prevalence of dhfr triple mutant and correlation with high rates of sulphadoxine-pyrimethamine treatment failures in vivo in Gabonese children Determination of the active stereoisomer of the MEP pathway-targeting antimalarial agent MMV008138, and initial structure-activity studies Inadequate efficacy of a new formulation of fosmidomycin-clindamycin combination in Mozambican children less than three years old with uncomplicated Plasmodium falciparum malaria.The global pipeline of new medicines for the control and elimination of malaria Expression, characterization and inhibition of Toxoplasma gondii 1-deoxy-D-xylulose-5-phosphate reductoisomerase.Assessment of safety of the major antimalarial drugs.Update on clindamycin in the management of bacterial, fungal and protozoal infections.FR-900098, an antimalarial development candidate that inhibits the non-mevalonate isoprenoid biosynthesis pathway, shows no evidence of acute toxicity and genotoxicity Drug repositioning in the treatment of malaria and TB.Fosmidomycin as an antimalarial drug: a meta-analysis of clinical trials.Exploring inhibition of Pdx1, a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum.Treating malaria in pregnancy in developing countries: priorities in clinical research and drug development.Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens.Phase I randomized dose-ascending placebo-controlled trials of ferroquine--a candidate anti-malarial drug--in adults with asymptomatic Plasmodium falciparum infection.In vitro activity of antifungal drugs against Plasmodium falciparum field isolates.David Roos. Interview by H. Craig Mak.Tropical medicine at the University of Tübingen.Drugs in Development for Malaria.

P2860

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P2860

Randomized controlled trial of fosmidomycin-clindamycin versus sulfadoxine-pyrimethamine in the treatment of Plasmodium falciparum malaria

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Antimicrobial Agents and Chemotherapy

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Fortune Barondi

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Sunny Oyakhirome

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P2860

Clindamycin as an antimalarial drug: review of clinical trials.

Fosmidomycin plus clindamycin for treatment of pediatric patients aged 1 to 14 years with Plasmodium falciparum malaria

Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs

In vitro and in vivo synergy of fosmidomycin, a novel antimalarial drug, with clindamycin.

Fosmidomycin-clindamycin for Plasmodium falciparum Infections in African children.

Fosmidomycin, a novel chemotherapeutic agent for malaria.

Fosmidomycin for the treatment of malaria.

Antimalarial combinations.

Comparison of chlorproguanil-dapsone with sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in young African children: double-blind randomised controlled trial.

New emerging Plasmodium falciparum genotypes in children during the transition phase from asymptomatic parasitemia to malaria.

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Michael Ramharter

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Plasmodium falciparum

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