Preclinical testing of candidate topical microbicides for anti-human immunodeficiency virus type 1 activity and tissue toxicity in a human cervical explant culture.
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Drug-eluting fibers for HIV-1 inhibition and contraceptionIs wetter better? An evaluation of over-the-counter personal lubricants for safety and anti-HIV-1 activityEfficacy of Carraguard-based microbicides in vivo despite variable in vitro activityAnimal and human mucosal tissue models to study HIV biomedical interventions: can we predict success?HSV-2-driven increase in the expression of α4β7 correlates with increased susceptibility to vaginal SHIV(SF162P3) infectionAn antiretroviral/zinc combination gel provides 24 hours of complete protection against vaginal SHIV infection in macaquesIn vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicideHSV neutralization by the microbicidal candidate C5ADrug synergy of tenofovir and nanoparticle-based antiretrovirals for HIV prophylaxisQuantitative analysis of microbicide concentrations in fluids, gels and tissues using confocal Raman spectroscopyEfficacy, stability, and biosafety of sifuvirtide gel as a microbicide candidate against HIV-1SPL7013 Gel (VivaGel®) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humansStructure activity relationship of dendrimer microbicides with dual action antiviral activityCaveats associated with the use of human cervical tissue for HIV and microbicide research.Ex vivo comparison of microbicide efficacies for preventing HIV-1 genomic integration in intraepithelial vaginal cellsDevelopment of topical microbicides to prevent the sexual transmission of HIVPVP-coated silver nanoparticles block the transmission of cell-free and cell-associated HIV-1 in human cervical culture.Safety and anti-HIV assessments of natural vaginal cleansing products in an established topical microbicides in vitro testing algorithm.HIV-1 transmission biology: selection and characteristics of infecting viruses.Variation in the biological properties of HIV-1 R5 envelopes: implications of envelope structure, transmission and pathogenesis.A MIV-150/zinc acetate gel inhibits SHIV-RT infection in macaque vaginal explantsMucosal immunity in the female genital tract, HIV/AIDSIn vitro evaluation of viability, integrity, and inflammation in genital epithelia upon exposure to pharmaceutical excipients and candidate microbicides.Preventing mucosal HIV transmission with topical microbicides: challenges and opportunities.Use of human mucosal tissue to study HIV-1 pathogenesis and evaluate HIV-1 prevention modalities.Rectal microbicide development.Poly(ethylene glycol) (PEG)-lactic acid nanocarrier-based degradable hydrogels for restoring the vaginal microenvironmentVaginal microbicide gel for delivery of IQP-0528, a pyrimidinedione analog with a dual mechanism of action against HIV-1.Vaginal microbiota and its role in HIV transmission and infection.The nonnucleoside reverse transcriptase inhibitor MIV-150 in carrageenan gel prevents rectal transmission of simian/human immunodeficiency virus infection in macaques.Distinct characteristics of endometrial and decidual macrophages and regulation of their permissivity to HIV-1 infection by SAMHD1.Modeling mucosal cell-associated HIV type 1 transmission in vitro.Formulation and characterization of polymeric films containing combinations of antiretrovirals (ARVs) for HIV preventionPeptide-derivatized SB105-A10 dendrimer inhibits the infectivity of R5 and X4 HIV-1 strains in primary PBMCs and cervicovaginal histoculturesVirucidal activity of the dendrimer microbicide SPL7013 against HIV-1.Semen enhances HIV infectivity and impairs the antiviral efficacy of microbicides.HIV-1 sexual transmission: early events of HIV-1 infection of human cervico-vaginal tissue in an optimized ex vivo model.Inhibition of the transport of HIV in vitro using a pH-responsive synthetic mucin-like polymer systemCervico-vaginal tissue ex vivo as a model to study early events in HIV-1 infection.Non-specific microbicide product development: then and now
P2860
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P2860
Preclinical testing of candidate topical microbicides for anti-human immunodeficiency virus type 1 activity and tissue toxicity in a human cervical explant culture.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Preclinical testing of candida ...... uman cervical explant culture.
@ast
Preclinical testing of candida ...... uman cervical explant culture.
@en
type
label
Preclinical testing of candida ...... uman cervical explant culture.
@ast
Preclinical testing of candida ...... uman cervical explant culture.
@en
prefLabel
Preclinical testing of candida ...... uman cervical explant culture.
@ast
Preclinical testing of candida ...... uman cervical explant culture.
@en
P2093
P2860
P356
P1476
Preclinical testing of candida ...... human cervical explant culture
@en
P2093
James E Cummins
Jeanine Bartlett
Jeannette Guarner
Lisa A Grohskopf
Lisa Flowers
Lynn Paxton
Patricia C Guenthner
Timothy Morken
P2860
P304
P356
10.1128/AAC.01129-06
P407
P577
2007-03-12T00:00:00Z