Evidence providing new insights into TOB-promoted deadenylation and supporting a link between TOB's deadenylation-enhancing and antiproliferative activities.
about
The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complexThe role of mammalian poly(A)-binding proteins in co-ordinating mRNA turnoverHeterogeneity and complexity within the nuclease module of the Ccr4-Not complexTrypanosome MKT1 and the RNA-binding protein ZC3H11: interactions and potential roles in post-transcriptional regulatory networks.Deadenylation of mRNA by the CCR4-NOT complex in Drosophila: molecular and developmental aspects.Multifunctional roles of the mammalian CCR4-NOT complex in physiological phenomena.Complex network-driven view of genomic mechanisms underlying Parkinson's disease: analyses in dorsal motor vagal nucleus, locus coeruleus, and substantia nigraInteraction between the poly(A)-binding protein Pab1 and the eukaryotic release factor eRF3 regulates translation termination but not mRNA decay in Saccharomyces cerevisiaeBTG2 bridges PABPC1 RNA-binding domains and CAF1 deadenylase to control cell proliferationMicroRNA-322 (miR-322) and its target protein Tob2 modulate Osterix (Osx) mRNA stability.The enzyme activities of Caf1 and Ccr4 are both required for deadenylation by the human Ccr4-Not nuclease module.Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach.TP53 Regulates Transcription of Cell Cycle GenesTP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertainThe influence of microRNAs and poly(A) tail length on endogenous mRNA-protein complexes.Alternative splicing of CNOT7 diversifies CCR4-NOT functions.BTG2 binds CCR4-NOT complexExtracellular-Regulated Kinases: Signaling From Ras to ERK Substrates to Control Biological Outcomes.
P2860
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P2860
Evidence providing new insights into TOB-promoted deadenylation and supporting a link between TOB's deadenylation-enhancing and antiproliferative activities.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Evidence providing new insight ...... antiproliferative activities.
@ast
Evidence providing new insight ...... antiproliferative activities.
@en
type
label
Evidence providing new insight ...... antiproliferative activities.
@ast
Evidence providing new insight ...... antiproliferative activities.
@en
prefLabel
Evidence providing new insight ...... antiproliferative activities.
@ast
Evidence providing new insight ...... antiproliferative activities.
@en
P2093
P2860
P356
P1476
Evidence providing new insight ...... antiproliferative activities.
@en
P2093
Ann-Bin Shyu
Chyi-Ying A Chen
Nader Ezzeddine
P2860
P304
P356
10.1128/MCB.06370-11
P407
P577
2012-01-17T00:00:00Z