Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma
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Histone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune TherapyATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichmentTranscriptional dissection of melanoma identifies a high-risk subtype underlying TP53 family genes and epigenome deregulationHistone variant H3F3A promotes lung cancer cell migration through intronic regulationHistoneDB 2.0: a histone database with variants--an integrated resource to explore histones and their variantsMultivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation.Downregulation of histone H2A and H2B pathways is associated with anthracycline sensitivity in breast cancer.BALB/c-congenic ANP32B-deficient mice reveal a modifying locus that determines viability.Oncogenic potential of histone-variant H2A.Z.1 and its regulatory role in cell cycle and epithelial-mesenchymal transition in liver cancer.The prognostic potential of alternative transcript isoforms across human tumors.Genome-wide identification of histone H2A and histone variant H2A.Z-interacting proteins by bPPI-seq.Histone Hypervariants H2A.Z.1 and H2A.Z.2 Play Independent and Context-Specific Roles in Neuronal Activity-Induced Transcription of Arc/Arg3.1 and Other Immediate Early Genes.H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCsPatching Broken DNA: Nucleosome Dynamics and the Repair of DNA BreaksEpigenomic landscape of melanoma progression to brain metastasis: unexplored therapeutic alternatives.Histone variants expression in peripheral blood mononuclear cells of patients with rheumatoid arthritis.Targeting epigenetic regulators for cancer therapy: modulation of bromodomain proteins, methyltransferases, demethylases, and microRNAs.Histone variants and melanoma: facts and hypotheses.Genetic complementation analysis showed distinct contributions of the N-terminal tail of H2A.Z to epigenetic regulations.ChIP-seq in studying epigenetic mechanisms of disease and promoting precision medicine: progresses and future directions.H3.Y discriminates between HIRA and DAXX chaperone complexes and reveals unexpected insights into human DAXX-H3.3-H4 binding and deposition requirements.Barcelona conference on epigenetics and cancer 2015: Coding and non-coding functions of the genome.Histone variant H2A.Z.2: A novel driver of melanoma progression.Dynamic changes in chromatin states during specification and differentiation of adult intestinal stem cellsRNF2 E3 or Not to E3: Dual Roles of RNF2 Overexpression in Melanoma.Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer.SUMO modification system facilitates the exchange of histone variant H2A.Z-2 at DNA damage sites.Harnessing BET Inhibitor Sensitivity Reveals AMIGO2 as a Melanoma Survival Gene.Brain-specific deletion of histone variant H2A.z results in cortical neurogenesis defects and neurodevelopmental disorder.Specific Acetylation Patterns of H2A.Z Form Transient Interactions with the BPTF Bromodomain.The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries.PWWP2A: A novel mitosis link?Recognition of histone acetylation by the GAS41 YEATS domain promotes H2A.Z deposition in non-small cell lung cancer.Characterization of mussel H2A.Z.2: a new H2A.Z variant preferentially expressed in germinal tissues from Mytilus.The tale of a tail: histone H4 acetylation and the repair of DNA breaks.Co-targeting BET and MEK as salvage therapy for MAPK and checkpoint inhibitor-resistant melanoma.H2A.Z regulates tumorigenesis, metastasis and sensitivity to cisplatin in intrahepatic cholangiocarcinoma.Altered primary chromatin structures and their implications in cancer development.Post-Translational Modifications of H2A Histone Variants and Their Role in Cancer.Epigenetic Modifications as Biomarkers of Tumor Development, Therapy Response, and Recurrence across the Cancer Care Continuum.
P2860
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P2860
Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma
@ast
Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma
@en
type
label
Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma
@ast
Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma
@en
prefLabel
Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma
@ast
Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma
@en
P2093
P2860
P50
P1433
P1476
Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma
@en
P2093
Amit Verma
Barbara Fontanals-Cirera
Chi-Yeh Chung
Chiara Vardabasso
Dan Hasson
Emily Bernstein
Eva C Keilhauer
Joanna Dong
Jonathan L Yao
Matthias Mann
P2860
P356
10.1016/J.MOLCEL.2015.05.009
P577
2015-06-04T00:00:00Z