The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription
about
Structural implications for K5/K12-di-acetylated histone H4 recognition by the second bromodomain of BRD2Histone recognition and large-scale structural analysis of the human bromodomain familyGene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activationThe role of human bromodomains in chromatin biology and gene transcriptionBrd2 gene disruption causes "metabolically healthy" obesity: epigenetic and chromatin-based mechanisms that uncouple obesity from type 2 diabetesEpigenetic inheritance: histone bookmarks across generationsSingle cell analysis of transcriptional activation dynamicsStructural Basis for Acetylated Histone H4 Recognition by the Human BRD2 BromodomainSuppression of inflammation by a synthetic histone mimicBET Inhibition Silences Expression of MYCN and BCL2 and Induces Cytotoxicity in Neuroblastoma Tumor ModelsHistone density is maintained during transcription mediated by the chromatin remodeler RSC and histone chaperone NAP1 in vitroThe Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous ProteinsH2A.Z: a molecular rheostat for transcriptional controlBromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genesFunctions of BET proteins in erythroid gene expressionBET domain co-regulators in obesity, inflammation and cancerA combination of H2A.Z and H4 acetylation recruits Brd2 to chromatin during transcriptional activationThe testis-specific double bromodomain-containing protein BRDT forms a complex with multiple spliceosome components and is required for mRNA splicing and 3'-UTR truncation in round spermatidsRegistered report: Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukemiaRegistered report: BET bromodomain inhibition as a therapeutic strategy to target c-MycControl of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genesSelf/nonself perception, reproduction and the extended MHCTargeting MYC dependence in cancer by inhibiting BET bromodomainsSelective inhibition of tumor oncogenes by disruption of super-enhancersBET bromodomain proteins and epigenetic regulation of inflammation: implications for type 2 diabetes and breast cancer.The C-terminal domain of Brd2 is important for chromatin interaction and regulation of transcription and alternative splicing.Bromodomain and extraterminal proteins suppress NF-E2-related factor 2-mediated antioxidant gene expression.Brd2 disruption in mice causes severe obesity without Type 2 diabetes.Regulation of iNOS gene transcription by IL-1β and IFN-γ requires a coactivator exchange mechanism.Pleiotrophin antagonizes Brd2 during neuronal differentiation.The BET protein FSH functionally interacts with ASH1 to orchestrate global gene activity in Drosophila.Writers and readers of histone acetylation: structure, mechanism, and inhibitionHistone deacetylase activity modulates alternative splicing.Brd4 engagement from chromatin targeting to transcriptional regulation: selective contact with acetylated histone H3 and H4.Bromodomain factors of BET family are new essential actors of pericentric heterochromatin transcriptional activation in response to heat shockBET Inhibitor JQ1 Blocks Inflammation and Bone Destruction.Application of Celluspots peptide arrays for the analysis of the binding specificity of epigenetic reading domains to modified histone tails.Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitorsMass spectrometric analysis of histone proteoforms.An emerging role for bromodomain-containing proteins in chromatin regulation and transcriptional control of adipogenesis.
P2860
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P2860
The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription
@ast
The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription
@en
The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription
@en-gb
The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription
@nl
type
label
The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription
@ast
The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription
@en
The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription
@en-gb
The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription
@nl
prefLabel
The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription
@ast
The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription
@en
The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription
@en-gb
The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription
@nl
P2093
P2860
P921
P3181
P1433
P1476
The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription
@en
P2093
Brenden Rickards
Gary LeRoy
P2860
P3181
P356
10.1016/J.MOLCEL.2008.01.018
P407
P577
2008-04-11T00:00:00Z