Alpha7 nicotinic acetylcholine receptors modulate motivation to self-administer nicotine: implications for smoking and schizophrenia. - Test2 - elhamkhani - TriplyDB

Alpha7 nicotinic acetylcholine receptors modulate motivation to self-administer nicotine: implications for smoking and schizophrenia.

Alpha7 nicotinic acetylcholine receptors modulate motivation to self-administer nicotine: implications for smoking and schizophrenia.

http://www.wikidata.org/entity/Q35837691

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Smoking cessation and reduction in people with chronic mental illness Molecular mechanisms underlying behaviors related to nicotine addiction Glutamatergic transmission in drug reward: implications for drug addiction Menthol binding and inhibition of α7-nicotinic acetylcholine receptors nAChR dysfunction as a common substrate for schizophrenia and comorbid nicotine addiction: Current trends and perspectives.Evaluating the role of the alpha-7 nicotinic acetylcholine receptor in the pathophysiology and treatment of schizophrenia.Compromised neuroplasticity in cigarette smokers under nicotine withdrawal is restituted by the nicotinic α4β2-receptor partial agonist varenicline.Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior.Merging old and new perspectives on nicotinic acetylcholine receptors Nicotine uses neuron-glia communication to enhance hippocampal synaptic transmission and long-term memory.Enhancing effect of menthol on nicotine self-administration in rats Genetic Variation of the Mu Opioid Receptor (OPRM1) and Dopamine D2 Receptor (DRD2) is Related to Smoking Differences in Patients with Schizophrenia but not Bipolar Disorder Nicotine and ethanol co-use in Long-Evans rats: Stimulatory effects of perinatal exposure to a fat-rich diet.Melatonin administration alters nicotine preference consumption via signaling through high-affinity melatonin receptors.Nicotinic receptor contributions to smoking: insights from human studies and animal models Development of novel pharmacotherapeutics for tobacco dependence: progress and future directions In vivo pharmacological interactions between a type II positive allosteric modulator of α7 nicotinic ACh receptors and nicotinic agonists in a murine tonic pain model.Not so Cool? Menthol's discovered actions on the nicotinic receptor and its implications for nicotine addiction.Positive allosteric modulation of α4β2 nicotinic acetylcholine receptors as a new approach to smoking reduction: evidence from a rat model of nicotine self-administration.Differential modulation of brain nicotinic acetylcholine receptor function by cytisine, varenicline, and two novel bispidine compounds: emergent properties of a hybrid molecule.Involvement of glutamatergic and GABAergic systems in nicotine dependence: Implications for novel pharmacotherapies for smoking cessation.Effects of blockade of α4β2 and α7 nicotinic acetylcholine receptors on cue-induced reinstatement of nicotine-seeking behaviour in rats.Genetic variation within the Chrna7 gene modulates nicotine reward-like phenotypes in mice.Alpha7 neuronal nicotinic receptors as a drug target in schizophrenia.Diverse strategies targeting α7 homomeric and α6β2* heteromeric nicotinic acetylcholine receptors for smoking cessation.The discriminative stimulus effects of i.v. nicotine in rhesus monkeys: Pharmacokinetics and apparent pA2 analysis with dihydro-β-erythroidine.New Targets for Schizophrenia Treatment beyond the Dopamine Hypothesis A behavioral economic perspective on smoking persistence in serious mental illness.In vivo interactions between α7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α: Implication for nicotine dependence.Initial Cross-Over Test of a Positive Allosteric Modulator of Alpha-7 Nicotinic Receptors to Aid Cessation in Smokers with or Without Schizophrenia.Role of the cholinesterase inhibitors in the treatment of schizophrenia.The current agonists and positive allosteric modulators of α7 nAChR for CNS indications in clinical trials.Nicotinic acetylcholine receptors in neuropathic and inflammatory pain.Attenuating Nicotine Reinforcement and Relapse by Enhancing Endogenous Brain Levels of Kynurenic Acid in Rats and Squirrel Monkeys.Unique Molecular Regulation of Higher-Order Prefrontal Cortical Circuits: Insights into the Neurobiology of Schizophrenia.Association and cis-mQTL analysis of variants in CHRNA3-A5, CHRNA7, CHRNB2, and CHRNB4 in relation to nicotine dependence in a Chinese Han population.GABAergic inhibitory neurons as therapeutic targets for cognitive impairment in schizophrenia.Pharmacological modulation of the α7 nicotinic acetylcholine receptor in a mouse model of mecamylamine-precipitated nicotine withdrawal.Current Concepts and Treatments of Schizophrenia

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Alpha7 nicotinic acetylcholine receptors modulate motivation to self-administer nicotine: implications for smoking and schizophrenia.

http://www.wikidata.org/entity/Q35837691

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Alpha7 nicotinic acetylcholine ...... for smoking and schizophrenia.

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Alpha7 nicotinic acetylcholine ...... for smoking and schizophrenia.

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Alpha7 nicotinic acetylcholine ...... for smoking and schizophrenia.

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Darlene H Brunzell

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J Michael McIntosh

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P2860

The chimeric gene CHRFAM7A, a partial duplication of the CHRNA7 gene, is a dominant negative regulator of α7*nAChR function

Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits

Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia

Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration

Evidence that nicotinic alpha(7) receptors are not involved in the hyperlocomotor and rewarding effects of nicotine.

Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors

Prevalence of smoking among psychiatric outpatients

A neurobiological basis for substance abuse comorbidity in schizophrenia

Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways

Operant sensation seeking engages similar neural substrates to operant drug seeking in C57 mice

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10.1038/NPP.2011.299

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