Akt blocks the tumor suppressor activity of LKB1 by promoting phosphorylation-dependent nuclear retention through 14-3-3 proteins.
about
Deletion of MLIP (muscle-enriched A-type lamin-interacting protein) leads to cardiac hyperactivation of Akt/mammalian target of rapamycin (mTOR) and impaired cardiac adaptationPI3K/Akt/mTOR signaling & its regulator tumour suppressor genes PTEN & LKB1 in human uterine leiomyomas.Costunolide and dehydrocostuslactone combination treatment inhibit breast cancer by inducing cell cycle arrest and apoptosis through c-Myc/p53 and AKT/14-3-3 pathway.A-674563, a putative AKT1 inhibitor that also suppresses CDK2 activity, inhibits human NSCLC cell growth more effectively than the pan-AKT inhibitor, MK-2206.Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility
P2860
Akt blocks the tumor suppressor activity of LKB1 by promoting phosphorylation-dependent nuclear retention through 14-3-3 proteins.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Akt blocks the tumor suppresso ...... ntion through 14-3-3 proteins.
@ast
Akt blocks the tumor suppresso ...... ntion through 14-3-3 proteins.
@en
type
label
Akt blocks the tumor suppresso ...... ntion through 14-3-3 proteins.
@ast
Akt blocks the tumor suppresso ...... ntion through 14-3-3 proteins.
@en
prefLabel
Akt blocks the tumor suppresso ...... ntion through 14-3-3 proteins.
@ast
Akt blocks the tumor suppresso ...... ntion through 14-3-3 proteins.
@en
P2093
P2860
P1476
Akt blocks the tumor suppresso ...... ention through 14-3-3 proteins
@en
P2093
P2860
P304
P407
P50
P577
2012-04-10T00:00:00Z