MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain - Test2 - elhamkhani - TriplyDB

MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain

MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain

http://www.wikidata.org/entity/Q35984230

about

The neurogenetics of alternative splicing Defective control of pre-messenger RNA splicing in human disease Report on the 3rd Ottawa International Conference on Neuromuscular Biology, Disease and Therapy - September 24-26, 2015, Ottawa, Canada.Expanded CCUG repeat RNA expression in Drosophila heart and muscle trigger Myotonic Dystrophy type 1-like phenotypes and activate autophagocytosis genes.Myotonic Dystrophies: State of the Art of New Therapeutic Developments for the CNS.RNA metabolism in neurodegenerative disease.A flow cytometry-based screen identifies MBNL1 modulators that rescue splicing defects in myotonic dystrophy type I.Distal Alternative Last Exons Localize mRNAs to Neural Projections Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy.Derepressing muscleblind expression by miRNA sponges ameliorates myotonic dystrophy-like phenotypes in Drosophila.Dysregulation of mRNA Localization and Translation in Genetic Disease Trinucleotide Repeat Expansion in the Transcription Factor 4 (TCF4) Gene Leads to Widespread mRNA Splicing Changes in Fuchs' Endothelial Corneal Dystrophy Paradoxical overexpression of MBNL2 in hepatocellular carcinoma inhibits tumor growth and invasion.Roles for RNA-binding proteins in development and disease.Dynamic landscape of alternative polyadenylation during retinal development.Alternative splicing as a regulator of development and tissue identity.Optical Mapping Approaches on Muscleblind-Like Compound Knockout Mice for Understanding Mechanistic Insights Into Ventricular Arrhythmias in Myotonic Dystrophy.TGC repeat expansion in the TCF4 gene increases the risk of Fuchs' endothelial corneal dystrophy in Australian cases.RAN Translation Regulated by Muscleblind Proteins in Myotonic Dystrophy Type 2.Reduced cytoplasmic MBNL1 is an early event in a brain-specific mouse model of myotonic dystrophy.Repeat-associated non-AUG (RAN) translation and other molecular mechanisms in Fragile X Tremor Ataxia Syndrome.Increased EEG Theta Spectral Power in Sleep in Myotonic Dystrophy Type 1.Quantitative Methods to Monitor RNA Biomarkers in Myotonic Dystrophy.rbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences.Core Clinical Phenotypes in Myotonic Dystrophies.Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism.Fuchs' Endothelial Corneal Dystrophy in Patients With Myotonic Dystrophy, Type 1.miR-23b and miR-218 silencing increase Muscleblind-like expression and alleviate myotonic dystrophy phenotypes in mammalian models.Control of CNS functions by RNA-binding proteins in neurological diseases

P2860

Q28069349-8472532C-257A-4183-B9FB-41A5CB388624 Q28077564-B853FDB5-25E9-4E5E-92A0-E3BCA1E33A7E Q30355125-FEB56D98-C6D9-46E5-85D3-790834B4E5CE Q30854929-D3CD6901-FCAC-434F-A790-89D903829BA9 Q33580885-FAB608B0-2E59-42D8-9736-E879C52CC46D Q33746283-0299F2EF-AA48-4F0A-A670-47696A201F69 Q36378612-C8A1875E-8E48-4DCD-B606-1F7720D98C3E Q36703465-F08483BC-5621-4ADA-A608-1820C3F6770C Q36796408-1312B944-9B34-4DCD-B58A-E97F93738A77 Q37386187-6CED3AE4-A5A3-4AA5-9469-61039413EF11 Q37444939-9589D6E6-AA7B-4756-AF56-64F351C5F61A Q37610130-3A888A9B-E142-4FEB-84DF-A6C05DFB2C66 Q37662278-4DF45A67-4EEA-43DA-B757-8DB4CDD0C875 Q38772987-3007139C-96EC-4A9F-B25B-524B43BA81C4 Q39090047-81C6631F-0524-4286-8C26-DE9A1D837145 Q39295240-007F7F66-4456-4834-9F20-4D43E17ABA1D Q41166103-94B4B914-B5D5-4A61-8618-671270CA7067 Q41498579-D4DA1FD9-FEC3-4E86-AB82-690DE0E7EAA7 Q47802363-85305425-8EF1-4FC7-817F-B1ED0ED1986E Q48233589-71AB175B-E183-427E-A1C1-31D6BDD84A43 Q49905433-A9EB0265-406A-4FDB-8BEA-5F8C7270A671 Q50210167-D3093182-33CB-4D3C-8EFE-6207E9DEF046 Q52322949-40F1D3AF-9D76-49AD-9D74-07781A7A138F Q55087601-1B4262CB-4A71-48DC-B665-384CF1F2CA7F Q55189250-80937AAA-DA75-4F24-99DC-C334447460CA Q55261655-79B01F96-852A-46A7-B5DE-804E933D8850 Q55281814-57F446EC-C592-41C1-8B64-B22BD0FD0561 Q55418837-FDFA9DD6-48F2-4357-96EB-8018CCC2C19C Q58566969-82A5F38A-F966-4C24-9978-BFA55E29480C

P2860

MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain

http://www.wikidata.org/entity/Q35984230

description

2015 nî lūn-bûn

@nan

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

@zh

2015年论文

@zh-cn

name

MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain

@ast

MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain

@en

type

label

MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain

@ast

MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain

@en

prefLabel

MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain

@ast

MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain

@en

P1433

Q35984230-44DE2AE4-926C-41D7-8463-04B208B419E2

P1476

Q35984230-4A7C8434-2F99-4FC0-BCF5-40E8E5D7B833

P2093

Q35984230-07B807B0-8770-4ECA-8CC1-02A2E664D749

Q35984230-16DC3FBB-7F8D-4BB9-83CF-975588B8AE9E

Q35984230-37507B2B-77FF-4FA8-B2C7-F30085BB01E0

Q35984230-44DF2740-CFA8-461B-8EBF-FBEC074F538D

Q35984230-46D6CD65-217F-4785-85D3-B8AF371116CB

Q35984230-46E5E296-1EBB-45E6-918E-57DA467339B2

Q35984230-4A145F0E-DD82-410F-95E3-FC12E333C63F

Q35984230-4B60CD81-EE62-4212-AB1B-F59327204868

Q35984230-541D64C9-33AD-431F-B351-028397F0F926

Q35984230-66E618E8-5780-4629-9939-3D46CA5A1816

P2860

Q35984230-1359CF39-E238-4F50-BAB0-5BA703E61187

Q35984230-13918C30-090A-4D13-879D-0D267CB89C53

Q35984230-1C588F3E-1CBF-4452-A928-DE62FBAD4419

Q35984230-1D50FE21-32C8-40B4-BBFA-94CA9EA60EF1

Q35984230-1ED33C01-FE65-4DA8-BC09-6EBC2E07EF44

Q35984230-228F0A22-E987-416F-8072-E34494FAB60A

Q35984230-33C74332-47D7-499D-9F3A-4FCD2F716969

Q35984230-3EBC3E08-55B9-4973-90FD-CB0BA451EF41

Q35984230-44CD2121-36EF-4937-A08B-29606B149DCE

Q35984230-4F6F8B42-5501-43AD-A781-D4C878AD4408

P304

Q35984230-F272EDFD-67FB-49FC-98AE-FD4383C300A1

P31

Q35984230-5374E7D6-AEEC-46B5-B478-E944D65E2A94

P356

Q35984230-EB5E3A58-E0CA-4958-AD70-B766F2EA1FF3

P433

Q35984230-69056ED2-6EA9-4D0C-A18B-24FE6E3B6419

P478

Q35984230-046D6DF0-ED2B-4337-8F41-F7C0DCB02EB8

P50

Q35984230-3B78C291-AC87-4266-9FAA-EADA188575B2

Q35984230-81B59716-7928-4A47-8281-C729306DE6B5

Q35984230-A1C31F24-E975-45B2-BAA6-174FAA035D1B

Q35984230-C199BEA7-C9C3-4F47-9EA8-7F55A44B4B30

P577

Q35984230-19EFD139-434C-43A4-9F49-FC3FAE94FEE4

P698

Q35984230-1B0AA505-C231-47E2-A2AC-9856E0A81619

P932

Q35984230-A6A73B82-7756-4264-AC00-A67998F8B483

P356

J.CELREP.2015.07.029

P1433

P1476

MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain

@en

P2093

Apoorva Mohan

http://www.w3.org/2001/XMLSchema#string

Chaolin Zhang

http://www.w3.org/2001/XMLSchema#string

H Brent Clark

http://www.w3.org/2001/XMLSchema#string

John W Day

http://www.w3.org/2001/XMLSchema#string

Joline Dalton

http://www.w3.org/2001/XMLSchema#string

Kenji Takamura

http://www.w3.org/2001/XMLSchema#string

Konstantinos Charizanis

http://www.w3.org/2001/XMLSchema#string

Kuang-Yung Lee

http://www.w3.org/2001/XMLSchema#string

Laura P W Ranum

http://www.w3.org/2001/XMLSchema#string

Marianne Goodwin

http://www.w3.org/2001/XMLSchema#string

P2860

Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy

Muscleblind proteins regulate alternative splicing

Muscleblind-like 2-mediated alternative splicing in the developing brain and dysregulation in myotonic dystrophy

Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps

HnRNP H inhibits nuclear export of mRNA containing expanded CUG repeats and a distal branch point sequence.

The unstable repeats--three evolving faces of neurological disease

A muscleblind knockout model for myotonic dystrophy

The RNA-binding protein Staufen1 is increased in DM1 skeletal muscle and promotes alternative pre-mRNA splicing

New function for the RNA helicase p68/DDX5 as a modifier of MBNL1 activity on expanded CUG repeats

Muscleblind-like 1 knockout mice reveal novel splicing defects in the myotonic dystrophy brain

P304

1159-1168

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.CELREP.2015.07.029

http://www.w3.org/2001/XMLSchema#string

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

12

http://www.w3.org/2001/XMLSchema#string

P50

Maurice S. Swanson

Francisco J Fernandez-Gomez

Nicolas Sergeant

P577

2015-08-06T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

26257173

http://www.w3.org/2001/XMLSchema#string

P932

4545389

http://www.w3.org/2001/XMLSchema#string