Structure-based dissociation of a type I polyketide synthase module
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Structural and Mechanistic Analysis of Protein Interactions in Module 3 of the 6-Deoxyerythronolide B SynthaseStructural Basis for Binding Specificity between Subclasses of Modular Polyketide Synthase Docking DomainsCrystal Structure of the Acyltransferase Domain of the Iterative Polyketide Synthase in Enediyne BiosynthesisStructure and Stereospecificity of the Dehydratase Domain from the Terminal Module of the Rifamycin Polyketide SynthaseProtein-protein recognition between acyltransferases and acyl carrier proteins in multimodular polyketide synthases.Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases.Programming of erythromycin biosynthesis by a modular polyketide synthaseArchitectures of whole-module and bimodular proteins from the 6-deoxyerythronolide B synthaseEvolution of Efficient Modular Polyketide Synthases by Homologous RecombinationHarnessing natural product assembly lines: structure, promiscuity, and engineering.Epimerase and Reductase Activities of Polyketide Synthase Ketoreductase Domains Utilize the Same Conserved Tyrosine and Serine Residues.Mechanism and specificity of an acyltransferase domain from a modular polyketide synthaseStructural analysis of protein-protein interactions in type I polyketide synthasesRevisiting the modularity of modular polyketide synthases.Coupled methyl group epimerization and reduction by polyketide synthase ketoreductase domains. Ketoreductase-catalyzed equilibrium isotope exchange.Structural insights into nonribosomal peptide enzymatic assembly linesMetabolic engineering is key to a sustainable chemical industry.The structural role of the carrier protein--active controller or passive carrier.Towards a new science of secondary metabolism.Steps towards the synthetic biology of polyketide biosynthesis.Dissecting complex polyketide biosynthesis.Assembly line polyketide synthases: mechanistic insights and unsolved problems.Mechanism based protein crosslinking of domains from the 6-deoxyerythronolide B synthase.The biochemical basis for stereochemical control in polyketide biosynthesis.A general scheme for synthesis of substrate-based polyketide labels for acyl carrier proteinsRecognition of acyl carrier proteins by ketoreductases in assembly line polyketide synthases.In vitro reconstruction of tetronate RK-682 biosynthesis.Stereospecificity of ketoreductase domains of the 6-deoxyerythronolide B synthaseRole of a conserved arginine residue in linkers between the ketosynthase and acyltransferase domains of multimodular polyketide synthases.In vivo and in vitro analysis of the hedamycin polyketide synthase.Stereospecificity of ketoreductase domains 1 and 2 of the tylactone modular polyketide synthase.A photocrosslinking assay for reporting protein interactions in polyketide and fatty acid synthases.Mechanism and Stereochemistry of Polyketide Chain Elongation and Methyl Group Epimerization in Polyether Biosynthesis.Dissecting how modular polyketide synthase ketoreductases interact with acyl carrier protein-attached substrates.Insights into the stereospecificity of ketoreduction in a modular polyketide synthase.Preparative, in vitro biocatalysis of triketide lactone chiral building blocks.
P2860
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P2860
Structure-based dissociation of a type I polyketide synthase module
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Structure-based dissociation of a type I polyketide synthase module
@ast
Structure-based dissociation of a type I polyketide synthase module
@en
type
label
Structure-based dissociation of a type I polyketide synthase module
@ast
Structure-based dissociation of a type I polyketide synthase module
@en
prefLabel
Structure-based dissociation of a type I polyketide synthase module
@ast
Structure-based dissociation of a type I polyketide synthase module
@en
P2093
P2860
P1476
Structure-based dissociation of a type I polyketide synthase module
@en
P2093
Alice Y Chen
Chaitan Khosla
David E Cane
P2860
P304
P356
10.1016/J.CHEMBIOL.2007.05.015
P577
2007-07-01T00:00:00Z