Insights into the stereospecificity of ketoreduction in a modular polyketide synthase.
about
Structural and Biochemical Studies of the Hedamycin Type II Polyketide Ketoreductase ( Hed KR): Molecular Basis of Stereo- and RegiospecificitiesStructural Studies of an A2-Type Modular Polyketide Synthase Ketoreductase Reveal Features Controlling α-Substituent StereochemistryStructural and Stereochemical Analysis of a Modular Polyketide Synthase Ketoreductase Domain Required for the Generation of a cis-AlkeneIdentification of the biosynthetic gene cluster for the antibiotic polyketide L-155,175 in Streptomyces hygroscopicus.Engineering polyketide synthases and nonribosomal peptide synthetases.Polyketide intermediate mimics as probes for revealing cryptic stereochemistry of ketoreductase domains.An erythromycin process improvement using the diethyl methylmalonate-responsive (Dmr) phenotype of the Saccharopolyspora erythraea mutB strainHarnessing natural product assembly lines: structure, promiscuity, and engineering.Rational reprogramming of fungal polyketide first-ring cyclizationPolyketide stereocontrol: a study in chemical biology.The structures of type I polyketide synthases.The structural role of the carrier protein--active controller or passive carrier.Dissecting complex polyketide biosynthesis.Genetic engineering of modular PKSs: from combinatorial biosynthesis to synthetic biology.Towards Precision Engineering of Canonical Polyketide Synthase Domains: Recent Advances and Future Prospects.Substrate structure-activity relationships guide rational engineering of modular polyketide synthase ketoreductases.Configurational assignment of secondary hydroxyl groups and methyl branches in polyketide natural products through bioinformatic analysis of the ketoreductase domain.Evaluating Ketoreductase Exchanges as a Means of Rationally Altering Polyketide Stereochemistry.Substrate-bound structures of a ketoreductase from amphotericin modular polyketide synthase.Insights into the programmed ketoreduction of partially reducing polyketide synthases: stereo- and substrate-specificity of the ketoreductase domain
P2860
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P2860
Insights into the stereospecificity of ketoreduction in a modular polyketide synthase.
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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name
Insights into the stereospecificity of ketoreduction in a modular polyketide synthase.
@en
Insights into the stereospecificity of ketoreduction in a modular polyketide synthase.
@nl
type
label
Insights into the stereospecificity of ketoreduction in a modular polyketide synthase.
@en
Insights into the stereospecificity of ketoreduction in a modular polyketide synthase.
@nl
prefLabel
Insights into the stereospecificity of ketoreduction in a modular polyketide synthase.
@en
Insights into the stereospecificity of ketoreduction in a modular polyketide synthase.
@nl
P2860
P50
P356
P1476
Insights into the stereospecificity of ketoreduction in a modular polyketide synthase.
@en
P2093
David H Kwan
Nadin Schläger
P2860
P304
P356
10.1039/C1OB00022E
P577
2011-02-21T00:00:00Z