Overexpressed hPTTG1 promotes breast cancer cell invasion and metastasis by regulating GEF-H1/RhoA signalling
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Stimulation of cortical myosin phosphorylation by p114RhoGEF drives cell migration and tumor cell invasionRhoGTPase signalling at epithelial tight junctions: Bridging the GAP between polarity and cancerCentral role of the exchange factor GEF-H1 in TNF-α-induced sequential activation of Rac, ADAM17/TACE, and RhoA in tubular epithelial cells.TGF-β regulates LARG and GEF-H1 during EMT to affect stiffening response to force and cell invasion.RalB regulates contractility-driven cancer dissemination upon TGFβ stimulation via the RhoGEF GEF-H1For robust big data analyses: a collection of 150 important pro-metastatic genesFolliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion.The SmgGDS splice variant SmgGDS-558 is a key promoter of tumor growth and RhoA signaling in breast cancer.Down-regulation of the oncogene PTTG1 via the KLF6 tumor suppressor during induction of myeloid differentiation.Microtubules regulate GEF-H1 in response to extracellular matrix stiffness.The PTTG1-targeting miRNAs miR-329, miR-300, miR-381, and miR-655 inhibit pituitary tumor cell tumorigenesis and are involved in a p53/PTTG1 regulation feedback loop.Minireview: Mouse Models of Rho GTPase Function in Mammary Gland Development, Tumorigenesis, and MetastasisHuman pituitary tumor-transforming gene 1 overexpression reinforces oncogene-induced senescence through CXCR2/p21 signaling in breast cancer cells.ADP-ribosylation factor 1 expression regulates epithelial-mesenchymal transition and predicts poor clinical outcome in triple-negative breast cancer.Intratumoral stages of metastatic cells: a synthesis of ontogeny, Rho/Rac GTPases, epithelial-mesenchymal transitions, and more.Altered expression of cellular proliferation, apoptosis and the cell cycle-related genes in lung cancer cells with acquired resistance to EGFR tyrosine kinase inhibitors.Knockdown of PTTG1 inhibits the growth and invasion of lung adenocarcinoma cells through regulation of TGFB1/SMAD3 signaling.Silencing RhoA inhibits migration and invasion through Wnt/β-catenin pathway and growth through cell cycle regulation in human tongue cancer.STAT3 is involved in esophageal carcinogenesis through regulation of Oct-1.Rho GTPases and cancer.Guanine nucleotide exchange factor H1 can be a new biomarker of melanoma.An oncogenic KRAS transcription program activates the RHOGEF ARHGEF2 to mediate transformed phenotypes in pancreatic cancer.The role of SATB1 in HTR8/SVneo cells and pathological mechanism of preeclampsia.Dual-specificity phosphatase 6 deficiency regulates gut microbiome and transcriptome response against diet-induced obesity in mice.Response of Myeloid Leukemia Cells to Luteolin is Modulated by Differentially Expressed Pituitary Tumor-Transforming Gene 1 (PTTG1) Oncoprotein.Overexpression of RhoA promotes the proliferation and migration of cervical cancer cells.
P2860
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P2860
Overexpressed hPTTG1 promotes breast cancer cell invasion and metastasis by regulating GEF-H1/RhoA signalling
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Overexpressed hPTTG1 promotes ...... ulating GEF-H1/RhoA signalling
@ast
Overexpressed hPTTG1 promotes ...... ulating GEF-H1/RhoA signalling
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type
label
Overexpressed hPTTG1 promotes ...... ulating GEF-H1/RhoA signalling
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Overexpressed hPTTG1 promotes ...... ulating GEF-H1/RhoA signalling
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prefLabel
Overexpressed hPTTG1 promotes ...... ulating GEF-H1/RhoA signalling
@ast
Overexpressed hPTTG1 promotes ...... ulating GEF-H1/RhoA signalling
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P2093
P2860
P356
P1433
P1476
Overexpressed hPTTG1 promotes ...... ulating GEF-H1/RhoA signalling
@en
P2093
J R Y Wang
P2860
P2888
P304
P356
10.1038/ONC.2011.476
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P577
2011-10-17T00:00:00Z