Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor
about
Molecular modeling of the human P2Y14 receptor: A template for structure-based design of selective agonist ligands.The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsDevelopment of selective agonists and antagonists of P2Y receptors.Human P2Y(14) receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups.UDP-glucose acting at P2Y14 receptors is a mediator of mast cell degranulationSignalling and pharmacological properties of the P2Y receptor.UDP is a competitive antagonist at the human P2Y14 receptorP2Y nucleotide receptors: promise of therapeutic applicationsExploring a 2-naphthoic acid template for the structure-based design of P2Y14 receptor antagonist molecular probesEnhanced potency of nucleotide-dendrimer conjugates as agonists of the P2Y14 receptor: multivalent effect in G protein-coupled receptor recognition.P2Y receptors in the mammalian nervous system: pharmacology, ligands and therapeutic potential.UDP-Sugars as Extracellular Signaling Molecules: Cellular and Physiologic Consequences of P2Y14 Receptor Activation.Design, synthesis, pharmacological characterization of a fluorescent agonist of the P2Y₁₄ receptor.Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists.The nucleotide sugar UDP-glucose mobilizes long-term repopulating primitive hematopoietic cells.Structural and functional evolution of the P2Y(12)-like receptor group.Molecular recognition in the P2Y(14) receptor: Probing the structurally permissive terminal sugar moiety of uridine-5'-diphosphoglucoseSelective induction of P2Y14 receptor by RANKL promotes osteoclast formation.Nucleoside 5'-O-monophosphorothioates as modulators of the P2Y14 receptor and mast cell degranulation.P2X and P2Y nucleotide receptors as targets in cardiovascular disease.Are GPCRs still a source of new targets?New agents in HSC mobilization.Development of a comprehensive set of P2 receptor pharmacological research compoundsCa(2+) signalling by P2Y receptors in cultured rat aortic smooth muscle cells.Toward the three-dimensional structure and lysophosphatidic acid binding characteristics of the LPA(4)/p2y(9)/GPR23 receptor: a homology modeling study.UDP-sugars activate P2Y14 receptors to mediate vasoconstriction of the porcine coronary artery.Mining human genome for novel purinergic P2Y receptors: a sequence analysis and molecular modeling approach.
P2860
Q27325455-A87E7EA5-2929-4CA0-8152-31997F8E8F7BQ30486707-1FD6C8AF-55EC-4ADE-B3E2-33A6F2BEBAAFQ33348980-AAF0A020-9B63-4298-A442-EFA6A65AECC6Q33584104-6226815C-68F8-4F17-A451-6297D0C69C2CQ33615486-8763325A-650B-48CF-85E3-B9538683D02CQ34033769-B171D027-E7BC-4BF2-8BB4-3944B3A71B34Q34053041-C0156DDF-FD04-4A90-90B4-C8D3D4CEA902Q34062142-B615A04E-A711-4585-9C85-CA9775D52FFBQ34756832-2B1DE07C-B615-4F45-A0AC-425F47DFAC16Q35020387-55CD54F4-D647-45BA-A913-B7C2E25B9A6FQ35163180-76CA77D4-9917-4653-BFA2-B1C098B5B7D5Q35745912-FAF943A0-DB4C-432B-B1DF-82F717194850Q36167203-3769F83D-1245-4982-B70D-21D8C9AEC8F3Q36790061-768FFDEB-A4E4-4302-B9F2-9EC9CCB77867Q37052874-9C18D531-CD99-4DE8-8075-802E266B8264Q37135510-D0041056-F75F-44A6-8B15-0F561DB0814FQ37383623-E60EFCCB-D35A-491C-9CBD-11E4AADAE0C1Q37462648-B247739E-B599-4C43-A68A-2238B1F15B01Q37688371-7A4E3498-AF7A-4932-A416-859B077A3EDEQ38089738-3FD4065B-D346-4973-8F23-D689F2D38B1AQ38129012-11741CDC-283D-4F5B-B44D-63BD7AA5E090Q39025249-10D78A35-BA8D-4894-B9DB-6D05660AD2D2Q40643618-A56CB556-6D20-4B72-B98B-32265E382128Q42150644-67840176-9B25-489C-AF16-598F7C0A336BQ42240327-4AA4AA5A-649B-4F12-97E7-77E88A8E4B1CQ47280784-FA86FF63-F0E0-46FF-BAA2-666CC33BD122Q54498590-6014B553-1CB7-4650-A5B1-28700E938307
P2860
Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Structure-activity relationshi ...... ts of the human P2Y14 receptor
@ast
Structure-activity relationshi ...... ts of the human P2Y14 receptor
@en
type
label
Structure-activity relationshi ...... ts of the human P2Y14 receptor
@ast
Structure-activity relationshi ...... ts of the human P2Y14 receptor
@en
prefLabel
Structure-activity relationshi ...... ts of the human P2Y14 receptor
@ast
Structure-activity relationshi ...... ts of the human P2Y14 receptor
@en
P2093
P2860
P356
P1476
Structure-activity relationshi ...... ts of the human P2Y14 receptor
@en
P2093
Andrei A Ivanov
Ingrid Fricks
Kenneth A Jacobson
T Kendall Harden
P2860
P304
P356
10.1021/JM061222W
P407
P577
2007-04-04T00:00:00Z